Cartalax Peptide Powder (AED) – Targeted Tripeptide for Cartilage & Connective Tissue Repair, Anti-Aging, and Epigenetic Research | High-Purity Bulk from China
Core Benefits
◆ Targeted cartilage and connective tissue
◆ Epigenetic regulation for anti-aging
◆ Promotes cartilage repair and regeneration
◆ Inhibits joint inflammation
◆ Reduces cellular senescence markers
◆ Enhances SIRT-6 expression
◆ Suitable for scientific research and formulation development
◆ High-purity bulk procurement from China at competitive pricing
Product Overview
Cartalax Peptide Powder (AED), also known as cartilage-regulating peptide, is a synthetic tripeptide developed by the St. Petersburg Institute of Bioregulation and Gerontology, Russia. Its amino acid sequence is Alanine-Glutamic acid-Aspartic acid (Ala-Glu-Asp, single-letter code AED). This acidic short-chain peptide is derived from the XI collagen α-1 chain fragment and naturally targets connective tissue.
Unlike traditional cartilage protection ingredients that act only on cell surface receptors, Cartalax Peptide Powder can penetrate the cell nucleus and bind directly to DNA minor groove sequences, regulating gene expression at the epigenetic level to support anti-aging and tissue repair. Preclinical studies confirm its efficacy in cartilage repair, joint inflammation mitigation, and cellular senescence regulation. Cartalax Peptide Powder is suitable for overseas scientific research, formulation development, and functional product R&D, addressing the limitations of traditional cartilage protection ingredients in targeting, depth of action, and safety.
COA
| Item | Specification | Result | |
| Appearance | White to off white powder | Conform | |
| Purity (HPLC) | ≥98.0% | 98.84% | |
| MS | Consistent | Consistent | |
| Conclusion | The product complies with the requirements. | ||
Mechanism of Action
Cartalax Peptide Powder (AED) operates through its collagen-derived tripeptide structure, connective tissue targeting, and nuclear penetration: target recognition → nuclear penetration → gene regulation → tissue repair. It reduces senescence markers, increases SIRT-6, promotes type II collagen and proteoglycan synthesis, inhibits MMP-9, modulates NF-κB, and enhances Ki-67/CD98hc expression. Its small molecule, water-soluble structure ensures high absorption, low immunogenicity, and safety, supported by extensive preclinical data.
Product Applications
● Pharmaceutical intermediates: Injectable and topical formulations for cartilage repair, anti-inflammation, anti-aging, connective tissue restoration.
● Scientific research material: Ideal for cartilage biology, epigenetics, cell aging, inflammation, connective tissue repair, skin anti-aging research.
● Functional ingredient: Suitable for dietary supplements, joint health, anti-aging, and skin care.
● Custom peptide development: Derivatives and long-acting peptides for joint health, anti-aging, and connective tissue repair product development.
Benefits of Products
1. Precise connective tissue targeting: Derived from XI collagen fragment, preferentially recognized by chondrocytes and fibroblasts. Bulk procurement in China provides cost-effective advantage.
2. Epigenetic anti-aging: Penetrates nuclei, binds DNA minor groove sequences (e.g., d(ATATATATA)₂), reduces p16, p21, p53, increases SIRT-6. Innovative mechanism supports anti-aging and epigenetic research.
3. Multi-functional synergy: Supports cartilage repair, anti-inflammation, connective tissue homeostasis, anti-aging, DNA repair.
4. High safety: No animal-derived contaminants, low immunogenicity, minimal toxicity. Preclinical and overseas applications confirm excellent tolerability.
Detailed Functions
1. Connective tissue regulation: Promotes proliferation and metabolism of chondrocytes and fibroblasts, supporting tissue homeostasis.
2. Epigenetic anti-aging: Regulates gene transcription, reduces senescence markers, increases SIRT-6, enhances DNA repair.
3. Cartilage repair: Activates chondrocyte differentiation, promotes type II collagen and proteoglycan synthesis, inhibits MMP-9, restores extracellular matrix integrity.
4. Anti-inflammatory: Modulates NF-κB signaling, reduces IL-1β, TNF-α, alleviating joint inflammation.
5. Cell metabolism & anti-apoptosis: Increases Ki-67, CD98hc, nutrient absorption, antioxidant effects, protects tissue integrity.
6. Multi-field research: Applicable in skin anti-aging, kidney epithelial aging, tendon and ligament regeneration, gene expression studies.
Core advantages
1. Mature GMP-controlled synthesis: Solid-phase peptide synthesis in 100,000-class cleanroom, monitoring impurities, endotoxins, and heavy metals.
2. Traceable quality: Batch-specific HPLC, MS, amino acid analysis, microbial and endotoxin reports; COA included.
3. Strong export compliance: Low allergenicity, meets the related standards. Full documentation provided.
4. Stable supply: Large-scale synthesis, sufficient inventory, fast response, fast global transport.
5. Technical support: Formulation guidance, application solutions, regulatory support, solution preparation.
Quality Assurance
● Raw material control: High-purity amino acids, no heavy metals or contaminants.
● Production control: GMP-compliant, sterile cleanroom synthesis.
● Testing control: HPLC, MS, moisture, acetate, TFA, microbial, endotoxin; batch-specific COA.
● Compliance control: Meets international peptide standards, full export documentation.
● After-sales control: Batch traceability, rapid issue resolution, technical support for bulk buyers.
FAQ
Q1: What makes Cartalax Peptide Powder different from traditional cartilage-protecting materials?
A: Cartalax Peptide Powder can penetrate the cell nucleus and regulate DNA activity, unlike traditional ingredients that mainly act on surface receptors. It helps reduce cellular senescence markers, supports cartilage repair, and provides targeted anti-inflammatory benefits.
Q2: Is Cartalax Peptide Powder suitable for formulation development?
A: Yes. It is compatible with injectable, topical, and functional product research. Its stability and safety profile make it suitable for cartilage repair and anti-inflammatory formulation studies.
Q3: What research dosage is recommended for scientific experiments?
A: In vivo studies commonly use 2–5 mg/day orally, while in vitro studies typically use 10–100 nM. Lower starting concentrations are recommended for evaluation.
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Ordering Information
Cartalax Peptide Powder (AED) offers a next-generation approach to cartilage and joint research with high purity, excellent stability, and advanced cellular targeting. Ideal for formulation development, anti-inflammatory studies, and connective tissue research, it provides reliable quality for global scientific applications. Contact us now for specifications, COA files, and bulk inquiry support.
Contact for Ordering:
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Email: sales@hdmbio.com
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