Elcatonin Powder GMP API Supplier in China | High-Purity Calcitonin Analog Bulk Manufacturer with Wholesale Price
Core Selling Points
- GMP-grade, ≥98% purity, stable batch-to-batch quality
- Enhanced stability with extended biological activity
- Strong osteoclast inhibition to reduce bone resorption
- Supports improved bone density and pain relief
- Low impurity profile, good solubility, high receptor affinity
- 2-year shelf life under standard storage conditions
- Factory-direct supply, OEM packaging, global wholesale support
What is Elcatonin Powder?
Elcatonin Powder is a synthetic peptide API derived from a structurally modified eel calcitonin analog. It is designed to enhance molecular stability, prolong biological activity, and improve pharmacological performance in bone metabolism regulation.
It consists of 31 amino acids with a cyclic peptide structure. The molecular formula is C₁₄₈H₂₄₄N₄₂O₄₇, and the molecular weight is approximately 3363.8 Da (CAS: 60731-46-6).
The product appears as a white to off-white powder manufactured through solid-phase peptide synthesis (SPPS) followed by multi-step high-performance liquid chromatography (HPLC) purification.
It is widely used in osteoporosis drug development, calcium metabolism research, and injectable formulation manufacturing.
What Does the COA of Elcatonin Powder Include?
|
Item |
Specification |
Result |
|
Appearance |
White to off White powder |
Consistent |
|
Purity(HPLC) |
≥99% |
99.33% |
|
MS |
Consistent |
Consistent |
|
Conclusion |
The product complies with the requirements |
|
What Are the Pharmacological Functions of Elcatonin Powder?
Elcatonin Powder exhibits multiple pharmacological activities related to bone metabolism regulation:
- Inhibits osteoclast-mediated bone resorption
- Regulates calcium homeostasis in blood and bone tissue
- Promotes bone mineral deposition and improves bone strength
- Provides analgesic effects in bone pain conditions
- Functions as a long-acting calcitonin receptor agonist
What Are the Key Advantages of Elcatonin Powder?
- Structurally stabilized analog with enhanced biological activity
- Improved resistance to oxidative degradation
- Prolonged pharmacological duration compared to natural calcitonin
- High bioactivity with strong receptor affinity
- Consistent batch-to-batch quality for industrial use
How Does Elcatonin Powder Work in Bone Metabolism?
Elcatonin Powder binds specifically to calcitonin receptors on osteoclasts, leading to inhibition of bone resorption activity.
It regulates calcium metabolism through dual mechanisms:
- Promotes calcium deposition into bone matrix
- Reduces renal tubular calcium reabsorption
How Does Elcatonin Powder Relieve Bone Pain?
It modulates central nervous system pathways involved in pain perception, particularly serotonergic (5-HT) signaling pathways, resulting in increased pain threshold.
It is effective in:
- Osteoporosis-related chronic pain
- Post-fracture bone pain
- Paget's disease-associated pain
What Are the Applications of Elcatonin Powder?
Elcatonin API is widely used in pharmaceutical and research applications:
- Osteoporosis treatment drug development
- Hypercalcemia therapy formulation
- Paget's disease drug research
- Bone pain management formulations
- Bone metabolism and endocrine research
What Are the Core Manufacturing Advantages?
- Elcatonin API is widely used in pharmaceutical and research applications:
- Osteoporosis treatment drug development
- Hypercalcemia therapy formulation
- Paget's disease drug research
- Bone pain management formulations
- Bone metabolism and endocrine research
FAQ
Q1: What is Elcatonin used for?
It is used for osteoporosis bone pain, Paget's disease, malignant hypercalcemia, and bone metabolism research.
Q2: What are common side effects of Elcatonin?
Nausea, facial flushing, dizziness, and mild injection site discomfort, mostly transient.
Q3: Is Elcatonin FDA approved?
No. It is approved in Japan and some Asian regions, not by the US FDA or EMA.
Q4: How is Elcatonin different from salmon calcitonin?
It replaces the disulfide bond with an ethylene bridge, with higher stability, longer half-life and lower immunogenicity.
factory
Certificates
Shipping & Packing
Contact & Cooperation
We provide stable GMP-grade Elcatonin Powder supply with full technical documentation, batch consistency, and global logistics support.
For quotation, samples, or technical documentation.
please contact:
WhatsApp: +8619991242181
Email:sales@hdmbio.com
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