HEP 1 Powder

HEP-1 Powder GMP Human Ezrin-Derived Immunomodulatory Peptide API | High Purity Antiviral Research Peptide Bulk Supply China

Key Product Highlights:

• 14-amino-acid Ezrin-derived peptide with antiviral and immunomodulatory activity
• Activates innate immunity to boost IFN-α/β expression
• Inhibits TNF-α, IL-6 and other pro-inflammatory cytokines
• Human-origin sequence ensures high biocompatibility
• Fully water-soluble for in vitro and in vivo research
• GMP-manufactured with low endotoxin and stable batch activity
• Every batch comes with complete COA and LC-MS validation

HEP 1 Powder (Human Ezrin Peptide 1) is a synthetic 14-amino-acid bioactive peptide derived from a functional fragment of the human Ezrin protein. It is widely used as a research-grade immunomodulatory peptide in virology, immunology, and inflammation-related studies.

The peptide exhibits dual biological activity by enhancing innate antiviral responses while simultaneously regulating excessive inflammatory signaling, making it a valuable tool for immune pathway research.

HEP-1 appears as a white to off-white sterile lyophilized powder with excellent aqueous solubility. It is manufactured via optimized Fmoc solid-phase peptide synthesis (SPPS), followed by multi-step RP-HPLC purification, desalting, and sterile lyophilization under GMP-compliant conditions.Typical applications include antiviral mechanism studies, immune signaling pathway research, and inflammatory disease model development.

1. Human-Origin Sequence Reduces Experimental Interference
2. Dual Immune Regulatory Activity
3. Excellent Aqueous Solubility
4. High Batch-to-Batch Consistency Under GMP Manufacturing
5. Low Endotoxin Suitable for Long-Term In Vivo Studies
6. Full Analytical Documentation Package

1. Induction of Interferon-Mediated Antiviral Response
2. NF-κB Pathway Modulation
3. Immune Homeostasis Regulation
4. CD4/CD8 Ratio Stabilization
5. Support for Long-Acting Peptide Formulation Research

• Optimized Short Peptide Synthesis Process
• Full GMP-Grade Quality Control System
• Flexible Manufacturing Scale
• Technical Support for Research Applications

• Binds immune cell membrane-associated receptors
• Activates IRF transcription factors to induce IFN-α/β expression
• Inhibits NF-κB nuclear translocation and inflammatory gene transcription
• Regulates Treg and effector T-cell balance
• Activates Nrf2-mediated antioxidant response pathways

• GMP-compliant cleanroom manufacturing environment
• Strict raw material qualification and supplier auditing
• Full batch traceability system with production records
• Long-term stability testing at -20°C (24-month validated data)
• Optional third-party analytical verification

Q: What is HEP 1 Powder?

A: It's lyophilized Human Ezrin Peptide 1 (Gepon), a 14-amino-acid synthetic peptide with CAS 174641-44-2, white research-grade powder for immune & antiviral study.

Q: What are the main research applications of HEP 1 Powder?

A: It's used for immunomodulation, antiviral (HIV/HCV/influenza) and anti-inflammation research, also to boost vaccine antibody titers in lab tests.

Q: What purity can I get for your HEP 1 Powder?

A: HPLC verified purity ≥98%, independent MS batch test reports (COA) provided upon request.

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