VIP Powder

High-Purity Vasoactive Intestinal Peptide (VIP) GMP Powder | Research-Grade Peptide API for Cardiovascular, Respiratory & Neuroimmune Studies (Bulk Supply from China)

Key Product Highlights:

• Stably activates VPAC1/VPAC2 receptors and elevates intracellular cAMP levels
• Provides vasodilation, smooth muscle relaxation and anti-inflammatory effects
• High water solubility supports in vitro and in vivo research applications
• Low impurities ensure stable and consistent biological activity per batch
• GMP production with full COA, LC-MS and sequence verification supplied

Vasoactive Intestinal Peptide (VIP Powder) is a 28-amino-acid endogenous neuropeptide belonging to the secretin–glucagon superfamily. It plays a key regulatory role in cardiovascular, respiratory, gastrointestinal, and neuroimmune systems.

VIP binds to VPAC1 and VPAC2 G-protein-coupled receptors, regulating vascular tone, smooth muscle relaxation, epithelial secretion, immune response, and neuroprotective pathways.

It is produced via Fmoc solid-phase peptide synthesis (SPPS), followed by RP-HPLC purification, desalting, and sterile lyophilization under GMP conditions, ensuring high purity and stable biological activity.

1. Stable VPAC receptor activation

Ensures consistent biological response in cAMP signaling studies.

2. Multi-system pharmacological activity

Applicable in cardiovascular, respiratory, gastrointestinal, and immune research models.

3. High solubility and experimental compatibility

Fully dissolves in aqueous buffers for in vitro and in vivo use.

4. Controlled impurity profile

Low oxidation and truncation levels ensure reproducible results.

5. Suitable for long-term animal studies

Low endotoxin levels support repeated-dose pharmacology experiments.

6. Full analytical documentation

Includes COA, HPLC, LC-MS, and sequence verification per batch.

VIP powder is synthetic Vasoactive Intestinal Peptide that interacts with VPAC1 and VPAC2 receptors distributed throughout biological tissues. After binding to target cell receptors, it activates cAMP signaling pathways to drive multi-system regulation: vasodilation in circulation, gastrointestinal motility and secretion adjustment, anti-inflammatory immune modulation, bronchial smooth muscle relaxation, and neuroprotective effects in neural tissue. It serves as a critical signaling mediator linking nervous, endocrine and immune systems, and purified VIP powder enables standardized in vitro and in vivo research on these biological regulatory mechanisms.

• Advanced Fmoc-SPPS peptide synthesis technology
• Multi-step RP-HPLC purification process
• GMP-certified cleanroom production environment
• Strict control of oxidation and truncated impurities
• Full batch traceability system from raw materials to final product
• Flexible production scale from milligram to kilogram

• GMP-compliant manufacturing system
• Raw material qualification and supplier auditing
• Full batch traceability documentation
• Long-term stability testing at -20°C (24 months)
• Optional third-party laboratory testing
• Multi-layer QC: HPLC, LC-MS, endotoxin, microbial limits

Q1: What is VIP peptide used for?

A: Vasoactive Intestinal Peptide (VIP Powder) is mainly applied in preclinical research on vasodilation, respiratory/intestinal regulation, neuroimmunology and anti-inflammatory drug screening.

Q2: What does VIP do to your body?

A: It activates VPAC receptors to raise cAMP levels, dilate blood vessels, relax smooth muscles and modulate immune inflammatory responses.

Q3: Is VIP a good peptide?

A: Yes, it has clear molecular mechanisms, stable bioactivity and wide adaptability for multi-disciplinary lab research with rigorous quality control.

Q4: How much VIP peptide to inject?

A: Dosage varies by animal species, model and administration route; optimize based on pre-existing pharmacology literature or preliminary lab trials.

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