High-Purity Eprinomectin Powder for Cattle, Sheep, Pigs & Rabbits – Lactation-Safe, Broad-Spectrum Veterinary Antiparasitic, Dual Internal & External Parasite Control, Wholesale China Supply
Highlighted Core Benefits
♦ Broad-spectrum macrolide antiparasitic, effective against both internal and external parasites
♦ Safe for lactating cows, with no milk withdrawal required
♦ No cross-resistance with other anthelmintics
♦ High lipophilicity for rapid absorption
♦ Stable physicochemical properties for long-term storage
♦ Compatible with multiple livestock species and dosage forms
♦ Compliant with international veterinary export standards
Product Overview
Eprinomectin Powder is a semi-synthetic macrolide veterinary antiparasitic agent derived from Streptomyces avermitilis. It is widely used for parasite control in cattle, sheep, pigs, rabbits, and other livestock, including dairy cattle without a milk withdrawal period.
It works by disrupting parasite neural signal transmission, effectively controlling gastrointestinal nematodes, lungworms, ticks, mites, lice, and fly larvae. Its unique mechanism helps reduce cross-resistance issues commonly seen with traditional antiparasitic products.
The product is a white or light yellow crystalline powder with high lipophilicity and excellent bioavailability. It is suitable for pour-on, injectable, premix, and feed formulations, supporting rapid absorption and long-lasting antiparasitic activity.
Manufactured under GMP and international veterinary standards, it offers ≥98.0% purity with high batch consistency and low impurities. Suitable for overseas veterinary formulation development and large-scale livestock parasite management applications.
Mechanism of Action
Eprinomectin Powder binds specifically to parasite neural synapse receptors, enhancing chloride ion permeability via GABA and glutamate-gated Cl⁻ channels. This blocks neural transmission, causing paralysis and death. Its high lipophilicity ensures rapid absorption, wide tissue distribution, and low mammalian toxicity due to protection by the blood-brain barrier in lactating animals.
Product Applications
◆ Core ingredient for long-acting veterinary dewormers in cattle, sheep, pigs, and rabbits
◆ Research reagent for macrolide mechanism, parasite resistance, and formulation development
◆ Custom formulations for group treatment, lactating cow dewormers, or synergistic blends
◆ Base ingredient for pour-on, injectable, and premix products
◆ Internal/external dual-effect dewormers for export markets
Detailed Efficacy
◇ Disrupts Pest Neural Signals: Targets GABA receptors, causing paralysis and loss of normal pest activity.
◇ Reduces Feeding & Reproduction: Helps stop pest feeding and disrupts population growth for long-term control.
◇ Stable in Outdoor Conditions: Resistant to rain and light degradation, suitable for agricultural and outdoor applications.
◇ Lower Non-Target Exposure: Lower skin and mucosal permeability helps reduce unnecessary environmental exposure.
◇ Flexible Formulation Compatibility: Compatible with plant extracts, additives, and multiple formulation types.
Product Benefits
1. Broad-spectrum parasite control: Effective against gastrointestinal nematodes, lungworms, ticks, mites, lice, and fly larvae
2. Safe for lactating cows: EU/FDA-approved broad-spectrum dewormer for lactating cows without milk withdrawal
3. No cross-resistance: Unique mechanism prevents resistance from other anthelmintics
4. High lipophilicity, rapid absorption: Peak plasma concentration within 2–4 hours; persists up to 63 days in dairy cattle
5. Low toxicity, high safety: Recommended dose 0.5–1.0 mg/kg BW; non-mutagenic, non-carcinogenic; overdose may cause mild ataxia or mydriasis
6. Global compliance: Meets the related standards; full export documentation for veterinary registration
factory
Certificates
Shipping & Packing
Core advantages
● High purity, stable batches
● Mature extraction and semi-synthetic process, GMP compliant
● Lactation-safe, no cross-resistance, dual internal/external efficacy
● Comprehensive testing and traceability (HPLC, MS, heavy metals, microbiology, impurities)
● Customizable packaging, fast shipping
● Full global export compliance (GMP, COA, MSDS, free sale certificates)
Quality Assurance
◆ Deep microbial fermentation, targeted semi-synthesis, and low-temperature crystallization in a sterile production environment, ensuring minimal impurities and by-products.
◆ Each batch tested via HPLC, MS, heavy metals, microbial limits; authoritative reports issued with traceable data.
◆ Sealed, light-proof, moisture-proof packaging.
◆ Produced under international GMP standards, suitable for overseas formulation, R&D, and custom applications.
◆ Full after-sales QA service; supports independent third-party testing to ensure consistency of purity, activity, and quality.
FAQ
Q1: Why is Eprinomectin suitable for lactating cows?
A1: The introduction of the -NHCOCH₃ group alters drug distribution in milk and blood. It is the only broad-spectrum anthelmintic approved by EU/FDA for use in lactating cows without milk discard. Withdrawal period: 24 hours.
Q2: How long does it act, and how often should it be administered?
A2: Due to high fat solubility and absorption, it lasts 35–42 days for rabbit ear mites and up to 63 days for dairy cow mites. Frequency can be reduced per breeding scenario, saving labor and costs.
Q3: Does it have cross-resistance with other anthelmintics?
A3: No, its unique mechanism avoids cross-resistance, enabling long-term control and rotation use.
Q4: What administration methods are suitable?
A4: Subcutaneous injection, topical pour-on, or mixed feed; suitable for large-scale farm operations.
Order Now
Order high-purity, lactation-safe, dual-effect Eprinomectin Powder for professional-grade veterinary dewormers in China. Ensure stable supply, full quality traceability, and regulatory compliance for global export.
Contact for Ordering:
Whatsapp & Mobile: +86 19991242181
Email: sales@hdmbio.com
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