Sulfadiazine Sodium API Powder Supplier China | ≥98% Sulfonamide Manufacturer CAS 547-32-0

Key Selling Points

✓ ≥98% HPLC Purity Sulfonamide API

✓ GMP-Aligned Production & Full Batch Traceability

✓ Batch COA, HPLC & Identity Verification

✓ Stable Bulk Supply from China

✓ Custom Packaging & OEM Service

✓ Global Export with Complete Customs Documents

What Is Sulfadiazine Sodium?

Sulfadiazine Sodium Powder is the water-soluble sodium salt of sulfadiazine, a synthetic sulfonamide antibacterial compound. It is supplied as a pharmaceutical and veterinary raw material and used in antimicrobial, formulation and laboratory research.

Its sodium-salt form provides substantially higher water solubility than sulfadiazine free base, making it suitable for applications requiring a water-soluble sulfadiazine material.

How Does Sulfadiazine Sodium Work?

Sulfadiazine Sodium Powder inhibits dihydropteroate synthase (DHPS), an enzyme involved in bacterial folate biosynthesis. By interfering with folic acid production, it limits the synthesis of compounds required for bacterial growth and replication.

This mechanism makes Sulfadiazine Sodium a useful reference compound for antimicrobial mechanism studies and bacterial folate-pathway research.

What Are the Applications of Sulfadiazine Sodium?

Pharmaceutical Manufacturing: Used as a sulfadiazine raw material for eligible pharmaceutical formulations.
Veterinary Pharmaceuticals: Used in veterinary antibacterial formulation development and manufacturing.
Antimicrobial Research: Used to study bacterial folate-pathway inhibition and DHPS-related mechanisms.
Toxoplasma Research: Used in laboratory studies involving Toxoplasma gondii, often evaluated with pyrimethamine.
Formulation Development: Suitable for solubility, formulation and process-development studies requiring a water-soluble sulfadiazine salt.

What Is the Difference Between Sulfadiazine and Sulfadiazine Sodium?

Feature	Sulfadiazine	Sulfadiazine Sodium
CAS	68-35-9	547-32-0
Solubility	Poorly water-soluble	Highly water-soluble sodium salt
Molecular Weight	250.28	272.26

How Does Sulfadiazine Sodium Compare With Other Sulfonamides?

Compound	CAS	Core Feature
Sulfadiazine Sodium	547-32-0	Water-soluble sodium salt with sulfonamide antibacterial activity
Sulfamethoxazole	723-46-6	Paired with trimethoprim (TMP-SMX)
Sulfadimidine Sodium	1981-58-4	Veterinary livestock antibacterial
Sulfachlorpyridazine Sodium	23282-55-5	Veterinary sulfonamide antibacterial applications

How Is Sulfadiazine Sodium Manufactured?

Raw Material QC → Chemical Synthesis → Purification → Crystallization → Drying → Final QC → Packaging

HDM BIO controls key synthesis, purification and drying parameters to maintain consistent purity and batch quality.

Quality Specifications

Test Item	Standard	Typical Result
Appearance	White to off-white powder	Consistent
Purity (HPLC)	≥98%	99.1%
Identity (IR/MS)	Conforms	Confirmed
Related Substances	Within specification	Pass
Loss on Drying	≤1.0%	0.3%
Heavy Metals	≤10 ppm	Compliant

What Quality Control Tests Are Performed for Sulfadiazine Sodium?

Each batch of Sulfadiazine Sodium undergoes multi-step quality control before release, including HPLC purity testing, identity verification, related-substance analysis, moisture testing and heavy-metal testing.

Raw Material QC → In-Process Control → HPLC Testing → Identity Verification → Impurity Testing → Final Batch Release

Every commercial batch is supported by a batch-specific COA and relevant analytical documentation for incoming QC and supplier qualification.

What Factors Affect Sulfadiazine Sodium Bulk Price?

Sulfadiazine Sodium bulk pricing depends on purity specification, order quantity, packaging requirements and destination. Contact HDM BIO for a current quotation and volume-based pricing.

Why Choose HDM BIO as Your Sulfadiazine Sodium Supplier?

China-based sulfonamide API manufacturer with large-scale production capacity
GMP-aligned production, ISO & HACCP certified quality system
Full batch traceability and complete documentation (COA, MSDS, HPLC)
Flexible supply: gram samples to ton-level bulk orders
Global export to 70+ countries with full customs support
Cost advantages and high adaptability for pharmaceutical and veterinary formulations

Bulk Packaging, Shipping & Storage

Packaging: Foil bags for samples and moisture-proof fiber drums for bulk orders.
Custom Packaging: OEM labeling available.
Shipping Documents: COA, MSDS/SDS, commercial invoice, packing list and customs documentation available according to order requirements.
Storage: Store tightly sealed in a cool, dry, light-protected environment. Shelf life: 24 months.
Handling: For pharmaceutical and veterinary raw material use only; not for direct clinical administration.

Frequently Asked Questions About Sulfadiazine Sodium

Q1: What is Sulfadiazine Sodium?

A: A synthetic sulfonamide antibiotic and water-soluble sodium salt of sulfadiazine, used for antibacterial research and pharmaceutical intermediate development.

Q2: What is the CAS number?

A: 547-32-0 (sodium salt); free base is 68-35-9.

Q3: Is it an antibiotic?

A: Yes, it is a broad-spectrum sulfonamide antibiotic that inhibits bacterial folic acid synthesis via DHPS inhibition.

Q4: How does it work?

A: It competitively inhibits dihydropteroate synthase (DHPS), blocking folic acid production needed for bacterial DNA/RNA replication.

Q5: Is it water soluble?

A: Yes. As a sodium salt, it is highly water-soluble, unlike the poorly soluble free base form.

Q6: What documents are provided with each batch?

A: Batch-specific COA, HPLC report, identity testing records, MSDS/SDS and relevant export documentation are available according to order requirements.

Q7: What purity do you supply?

A: Standard ≥98% HPLC; higher grades available on request.

Q8: Where can I buy it from China?

A: HDM BIO supplies bulk Sulfadiazine Sodium powder with batch COA and global export support.

Q9: How much does Sulfadiazine Sodium API cost?

A: Bulk pricing depends on purity specification, order quantity, packaging, destination and current production conditions. Contact HDM BIO for a current quotation and volume-based pricing.

Q10: Is this product for clinical use?

A: It is supplied as pharmaceutical/veterinary raw material and is not intended for direct clinical administration. Finished products manufactured from the material must comply with applicable local regulatory requirements.