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Adipotide Peptide Powder

Adipotide Peptide Powder

Appearance: White to off white powder
Specification: 98% min
CAS Number: 335591-03-2
Molecular Formula: C₁₇H₂₆N₄O₉
Molecular Weight: 430.41
Shelf Life: 2 Years Proper Storage
Stock: Fresh Stock
Certificate: COA,GMP,ISO,HACCP
Service: OEM&ODM Service

Product Introduction

High-Purity Adipotide Peptide Powder | Targeted Fat-Loss Peptide for Research & Formulation Development | Bulk Supply Available

Core Selling Points
Fat-Vessel Targeted Apoptosis | Reduces White Fat Accumulation | Improves Insulin Sensitivity | Regulates Metabolic Markers | Alleviates Fat Tissue Inflammation | Suitable for Research and Formulation Development 

 

Product Overview

 

Adipotide Peptide Powder (also known as FTPP, Fat-Targeting Pro-apoptotic Peptide) is a synthetic bifunctional chimeric peptide developed by the MD Anderson Cancer Center, University of Texas. It belongs to vascular-targeted apoptosis peptides (VTA) and is a highly selective fat-targeting peptide raw material for fat reduction.

 

Its unique molecular structure consists of a fat-vessel targeting cyclic peptide domain, a flexible linker region, and a mitochondrial-targeting pro-apoptotic domain. This structure allows it to specifically recognize endothelial cells in adipose tissue vasculature, inducing apoptosis and cutting off nutrient supply to adipocytes, achieving precise fat reduction. Unlike traditional fat-loss approaches that only regulate metabolism or suppress appetite, Adipotide Peptide Powder addresses fat accumulation at its source.

 

COA

 

Item Specification Result
Appearance White to off white powder Conform
Purity (HPLC) ≥98.0% 98.28%
MS Consistent Consistent
Conclusion The product complies with the requirements.

 

Mechanism of Action

 

Adipotide's three-domain structure enables "targeting–internalization–apoptosis" mechanism. N-terminal cyclic peptide binds Annexin A2 in fat vasculature, internalization occurs, flexible linker ensures independent function of targeting and apoptotic domains. C-terminal mitochondrial domain disrupts membrane potential, activating caspase cascade, inducing endothelial apoptosis. Resulting vascular regression cuts nutrient supply, inducing secondary apoptosis in fat cells. Regulates inflammatory cytokines and improves insulin sensitivity, providing multi-pathway metabolic regulation.

 

Product  Applications

 

1. Pharmaceutical Intermediate:
For fat-loss, metabolic regulation, anti-inflammatory injectable, oral, or topical formulations. Suitable for obesity, metabolic syndrome, type 2 diabetes, NAFLD research. 

2. Research Raw Material:
For adipose metabolism, obesity mechanisms, metabolic disorders, inflammation, and tumor targeting studies. Supports endothelial apoptosis, metabolic regulation, and cytokine studies.

3. Functional Ingredient:
For high-end dietary supplements, weight management, metabolic regulation, skincare products. 

4. Custom Peptide Development:
For Adipotide derivatives and long-acting targeted fat-loss peptides, enabling novel fat-reduction and metabolic-regulating products.Bulk procurement of Adipotide Peptide Powder can enjoy technical support and price advantages.

 

Benefits of Products

 

● Targeted Fat-Tissue Activity
Designed to selectively target adipose tissue pathways while minimizing off-target effects in non-fat tissues.

● Unique Fat-Loss Mechanism
Supports fat-reduction research through adipose tissue regulation rather than appetite suppression pathways.

● Metabolic Research Potential
Applicable to metabolic regulation, insulin sensitivity, inflammation, and weight-management studies.

● Supported by Preclinical Research
Preclinical studies demonstrate promising effects in body composition and metabolic research models.

● Flexible Purity & Packaging Options
Available in multiple purity grades and packaging sizes for laboratory research, pilot studies, and bulk production.

 

Detailed Functions

 

●Targeted Adipose Tissue Regulation
Designed to selectively target fat-tissue vascular pathways and support adipose reduction research.

● Body Composition Research Support
Applicable to studies involving visceral fat, abdominal fat, and metabolic body composition regulation.

● Metabolic Function Research
Supports research on insulin sensitivity, glucose metabolism, lipid balance, and fatty liver-related pathways.

● Inflammation Modulation Potential
Helps regulate inflammatory signaling associated with adipose and metabolic research models.

● Healthy Aging Research Applications
Applicable to studies involving metabolic aging, visceral fat accumulation, and age-related metabolic function.

● Expanded Research Potential
Can be explored in vascular-targeting and multi-pathway peptide research applications.

 

Core advantages

 

1. Mature and Controllable Process
Standardized solid-phase peptide synthesis in a High-Class cleanroom, strictly following GMP regulations. Impurities, endotoxins, heavy metals, and solvent residues are strictly controlled.

2. Traceable Quality
Each batch includes HPLC, amino acid sequence, microbial, and endotoxin reports. Complete COA ensures development and export reliability.

3. Strong Export Compliance
Meeting international standards. Full MSDS, COA, and support for customs clearance.

4. Stable and Efficient Supply
Scalable production with sufficient inventory, customizable packaging, low-temperature shipping, ensuring timely supply for bulk procurement.

5. Technical Support
Expert peptide R&D team offers formulation optimization, application guidance, regulatory support, and experimental advice.

 

Quality Assurance 

 

1.  Raw Material Control: High-purity amino acids, strictly screened reagents, ensures sequence accuracy and structural integrity for Adipotide Peptide Powder.

2.  Production Control: GMP cleanroom production, controlling temperature, humidity, and sterility.

3. Testing Control: HPLC and MS verification, moisture, acetate, microbial, endotoxin testing; complete batch COA.

4. Compliance Control: Meets international peptide raw material standards; full export compliance documents available.

5.  After-Sales Control: Batch traceability, unique batch numbers, rapid troubleshooting and technical solutions.

 

FAQ

 

Q1: How does Adipotide differ from conventional fat-loss ingredients ?
A: Conventional ingredients affect appetite or absorption; Adipotide targets fat vasculature, inducing apoptosis for precise fat reduction, improving metabolic markers, reducing inflammation, safer and more effective. Bulk Chinese procurement offers competitive pricing.

 

Q2: Is it suitable for formulation development?
A: Extensive preclinical studies show significant fat-loss and metabolic benefits. Suitable for injectable, oral, topical formulations.

 

Q3: What dosage is recommended for research?
A: Preclinical reference: 0.1–0.43 mg/kg daily for 4–6 weeks. Start low, monitor tolerance and markers; technical guidance available.
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factory

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Certificates

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Shipping & Packing

 

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Order Now

 

High-purity, stable, compliant Adipotide Peptide Powder suitable for research, formulation, and functional product development.

Contact us for samples, bulk procurement, or customized services.


Whatsapp & Mobile: +86 19991242181

Email: sales@hdmbio.com

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