N-Acetyl Selank Amidate Peptide | High-Purity Dual-Modified Compound for Cognitive & Neuroimmune Research
Core Benefits
High-Purity N-Acetyl Selank Amidate | BBB-Penetrating Dual-Modified Peptide | GMP-Compliant Bulk Supply for Cognitive & Neuroimmune Research
Product Overview
N-Acetyl Selank Amidate is a second-generation stabilized derivative of the classic neuroregulatory peptide Selank, developed by the Russian Academy of Sciences. This synthetic neuroimmune-modulatory peptide is optimized through N-terminal acetylation and C-terminal amidation, enhancing chemical stability, enzymatic resistance, and bioavailability while preserving the core biological activity of Selank.
The dual-modified structure addresses common research pain points of traditional Selank, such as poor stability, short half-life, and limited blood-brain barrier penetration. It precisely targets GABA and serotonin systems, activates BDNF expression, inhibits pro-inflammatory cytokine release, and exhibits neuroregulatory, immune-modulatory, neuroprotective, and cognition-enhancing effects, well-supported by preclinical and literature data.
It is fully compliant with GMP standards, every batch is third-party verified, free from unknown harmful substances, and suitable for small- to large-scale research, pharmacological testing, mechanism studies, and formulation screening.
COA
| Item | Specification | Result | |
| Appearance | White to off white powder | Consistent | |
| Purity (HPLC) | ≥98.0% | 99.06% | |
| MS | Consistent | Consistent | |
| Conclusion | The product complies with the requirements | ||
Mechanism of Action
▲ Targeted Penetration: Dual-modified structure crosses Blood-Brain Barrier, reaching CNS and immune tissues for dual neuroimmune regulation.
▲ Neurotransmitter Modulation: Specifically regulates GABA and serotonin systems, enhancing GABAergic inhibition, modulating anxiety/stress without sedation.
▲ Signal Activation: Activates BDNF, promoting synapse formation, dendritic spine development, neuronal survival; suppresses pro-inflammatory cytokines.
▲ Sustained Activity: Dual modification shields cleavage sites, prolonging half-life and bioavailability, ensuring consistent experimental effects.
Product Applications
N-Acetyl Selank Amidate is an optimized synthetic regulatory peptide with potential applications in neuroscience, mental health and neuroimmune research.
▲ Anxiolytic & Emotional Support
Helps regulate neurotransmitter balance and stress-related neural pathways, supporting emotional stability and calm mental states without sedative effects.
▲ Cognitive Support
Supports attention, memory and information processing while helping reduce mental fatigue, brain fog and stress-related cognitive decline.
▲ Neuroimmune Regulation
Modulates neuroimmune interactions, helping balance inflammatory responses and maintain nervous system homeostasis.
▲ Neuroprotective Effects
Protects neurons from oxidative and stress-related damage while supporting synaptic stability and healthy neural function.
▲ Sleep & Recovery Support
Helps regulate sleep-wake cycles and improve sleep quality under stress conditions, supporting nervous system recovery.
Detailed Efficacy
▲ Dual-Modified Stability
N-terminal acetylation and C-terminal amidation enhance stability, improve bioavailability, and extend peptide half-life.
▲ Efficient BBB Penetration
Optimized structure supports effective blood-brain barrier penetration and direct CNS targeting.
▲ Multi-Pathway Neuroregulation
Modulates GABA and serotonin pathways, supports BDNF activity, and helps regulate neuroinflammatory responses..
▲ Flexible Research Applications
Water- and buffer-soluble, suitable for in vitro and experimental research use.
Core Advantages
▲ Advanced Peptide Engineering
Rationally optimized molecular design improves structural integrity and research adaptability across diverse experimental environments.
▲ High Research Efficiency
Supports streamlined experimental workflows with stable handling properties and reduced formulation complexity.
▲ Broad Formulation Compatibility
Suitable for integration into peptide blends, liquid systems, lyophilized formulations, and customized research preparations.
▲ Low Interference Research Profile
Demonstrates minimal impact on normal behavioral activity, supporting clearer interpretation of experimental data.
▲ Reliable Scale-Up Capability
Consistent manufacturing processes enable smooth transition from pilot-scale studies to larger research procurement programs.
Quality Assurance
1. Comprehensive Testing: Purity, peptide content, impurities, moisture, heavy metals, endotoxin; HPLC, MS, amino acid analysis; third-party validation included.
2. Traceable Batches: Unique batch ID, full production/testing/dispatch record, supporting global compliance.
3. Professional Storage & Transport: Vacuum-sealed, protected from light/moisture/oxidation, fast delivery.
FAQ
Q1: What is N-Acetyl Selank Amidate?
A1: It is a dual-modified Selank derivative with N-terminal acetylation and C-terminal amidation, offering higher stability, longer half-life, and improved blood-brain barrier (BBB) penetration than regular Selank.
Q2: How soluble is it?
A2: Easily soluble in water, saline, phosphate-buffered saline, or DMSO. Recommended stock: 1–5 mg/mL.
Q3:What's the difference between Selank and N‑Acetyl Selank Amidate?
A3: Acetylation and amidation improve peptide stability and metabolic resistance.
factory
Certificates
Shipping & Packing
Purchase Now
Procure high-purity N-Acetyl Selank Amidate peptide now. Flexible sample, small-to-large batch supply, fast global delivery, one-to-one technical support.
Contact:
Whatsapp & Mobile: +86 19991242181
Email: sales@hdmbio.com
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