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Biotinoyl Tripeptide-1 Powder

Biotinoyl Tripeptide-1 Powder

Appearance: White to off white powder
Specification: 98% min
CAS Number: 299157-54-3
Molecular Formula: C24H38N8O6S
Molecular Weight: 566.68
Shelf Life: 2 Years Proper Storage
Stock: Fresh Stock
Certificate: COA,GMP,ISO,HACCP
Service: OEM&ODM Service

Product Introduction

Biotinoyl Tripeptide-1 Powder | GMP Cosmetic Peptide Raw Material Manufacturer & Bulk Supplier

Key Points:

✓ For lash, brow and hair care: enhances the thicker, fuller appearance of lashes, brows and scalp hair

✓ Biotin-conjugated structure: high affinity to hair keratin for consistent formulation performance

✓ Improves the look of stronger, more resilient hair strands

✓ ≥98% HPLC purity, excellent compatibility with serum, gel and emulsion systems

✓ GMP-compliant production with full COA & MS documentation

✓ Flexible supply from 1g samples to customized bulk orders

 

What Is Biotinoyl Tripeptide-1 Powder and Why Is It Used in Cosmetic Formulations?

 

HDM BIO is a China-based Biotinoyl Tripeptide-1 manufacturer supplying bulk powder for global skincare brands, cosmetic formulators, and private-label manufacturers.

 

The Biotinoyl Tripeptide-1 Powder molecule is synthesized using solid-phase peptide synthesis (SPPS) techniques to ensure high chemical purity and structural integrity. As a biotin-conjugated peptide ingredient, Biotinoyl Tripeptide-1 is commonly used in eyelash, eyebrow, and hair care cosmetic formulations where formulators seek peptide-based cosmetic solutions with reliable quality and documentation.

 

Formulators select this ingredient due to its exceptional purity, reliable performance in various systems, and comprehensive regulatory documentation. HDM BIO's peptide portfolio supports developers in creating high-performance products with globally compliant ingredients.

 

How Is Biotinoyl Tripeptide-1 Powder Quality Verified?

 

Every batch of Biotinoyl Tripeptide-1 Powder undergoes rigorous analytical testing at HDM BIO's quality control laboratory to verify its physicochemical properties and purity.

 

Item

Specification

Result

Appearance

White to off white powder

Consistent

Purity(HPLC)

≥98%

99.33%

MS

Consistent

Consistent

Conclusion

The product complies with the requirements

 

What Are the Core Product Benefits?

 

  • Verified purity supporting consistent formulation performance in cosmetic applications.
  • Features biotin (vitamin B7) conjugation designed for compatibility with hair and lash cosmetic formulations.
  • Reliable batch consistency supporting large-scale commercial manufacturing.
  • Full technical documentation for international regulatory compliance.
  • Scalable supply chain from laboratory samples to industrial quantities.
  • OEM and ODM capability for customized peptide concentration and formats.

 

Why Do Cosmetic Formulators Choose Biotinoyl Tripeptide-1 Powder?

 

Cosmetic formulators choose Biotinoyl Tripeptide-1 Powder because of its excellent formulation compatibility, formulation versatility and targeted keratin affinity, and reliable batch consistency.

 

Its physicochemical properties allow integration into various skincare systems, including serums, gels, and emulsion-based systems. The ingredient is supplied with comprehensive quality documentation that supports cosmetic product registration and compliance requirements.

 

The ingredient is commonly selected by cosmetic brands developing premium eyelash, brow, and hair care products that require consistent quality and reliable supply. As an experienced bulk peptide supplier, HDM BIO provides technical support for formulation integration, helping brands move efficiently from development to commercial production.

 

What Types of Cosmetic Products Commonly Include Biotinoyl Tripeptide-1 Powder?

 

  • Eyelash enhancement serums - Used as a signature biotin-conjugated peptide in lash care formulations.
  • Eyebrow grooming products - Suitable for brow definition and appearance-focused cosmetics.
  • Scalp care treatments - Selected for formulations targeting the appearance of fuller-looking hair.
  • Hair serums - Compatible with leave-in and rinse-off hair care product systems.
  • Multi-functional lash and brow kits - Applied in combined cosmetic peptide beauty routines.
  • Professional salon products - Used by salon brands for care-focused hair care lines.
  • Private-label lash and brow collections - Available for customized OEM beauty product development.

 

How Is Biotinoyl Tripeptide-1 Powder Manufactured Under GMP Conditions?

 

The production of Biotinoyl Tripeptide-1 Powder follows a strictly controlled chemical synthesis process to ensure maximum purity and minimal byproduct formation.

  • Resin Loading - Initialization of the synthesis process on a functionalized resin.
  • Sequential Coupling - Stepwise coupling of the three amino acids in the sequence.
  • Biotin Conjugation - N-terminal biotin attachment to the peptide chain on the resin.
  • Cleavage - Removal of the biotinylated peptide from the solid support.
  • HPLC Purification - Purification to achieve cosmetic ingredient grade purity ≥98%.
  • Lyophilization - Freeze-drying to obtain the final biotinoyl tripeptide powder.
  • Final QC Release - Multi-point verification including mass spectrometry confirmation.

The entire process is performed in HDM BIO's GMP-compliant facility with environmental monitoring, personnel training records, and equipment validation programs in place.

 

What Quality Assurance Processes Support Every Production Batch?

 

HDM BIO maintains a robust quality management system that monitors every phase of the peptide production cycle.

  • Raw material qualification ensuring high-grade precursors
  • In-process controls during each coupling and purification cycle
  • Purification verification via analytical HPLC
  • Batch release testing covering all specified parameters
  • Documentation package including COA, MS, and HPLC data
  • Retained sample program for long-term quality monitoring
  • Stability-oriented packaging in controlled environments

 

What Other Cosmetic Peptide Ingredients Does HDM BIO Manufacture?

 

  • Biotinoyl Tripeptide-1 Powder is part of HDM BIO's complete [cosmetic peptide ingredients] portfolio, which includes advanced matrikines and signaling peptides.
  • [Tripeptide-1 peptide powder] (GHK) - copper-binding tripeptide
  • [Palmitoyl Tripeptide-1 Powder] (Pal-GHK) - Matrixyl family lipid peptide
  • Dipeptide-6 Powder - short-chain age-defying dipeptide
  • Palmitoyl Tripeptide-38 (Matrixyl Synthe'6) Powder - ECM-targeting matrikine lipopeptide
  • Tripeptide-29 Powder - collagen-signaling tripeptide
  • Acetyl Dipeptide-1 Cetyl Ester Powder - lipid-modified skin firming dipeptide

 

Frequently Asked Questions About Biotinoyl Tripeptide-1 Powder

 

Q:What is Biotinoyl Tripeptide-1 Powder used for in cosmetics?

Biotinoyl Tripeptide-1 Powder is used as a bioactive raw material in advanced hair, lash and brow care formulations. It is selected by formulators for its documented compatibility in improving the appearance of hair and lash texture and supporting premium cosmetic product performance. Its high purity and stability make it suitable for premium cosmetic brands globally.

 

Q:Is Biotinoyl Tripeptide-1 Powder water-soluble?

A: Biotinoyl Tripeptide-1 is moderately soluble in water and highly compatible with serum and gel-based systems. For optimal incorporation, formulators may use glycols or other solvents common in hair and lash care formulations to ensure complete dissolution and stability of the biotin-conjugated peptide within the final cosmetic product.

 

Q:What usage concentration is typical?

A: Typical usage levels for this ingredient depend on formulation design, product type, and supplier recommendations. Formulators should determine the appropriate concentration through formulation development, stability testing, and compatibility evaluation.

 

Q:How is Biotinoyl Tripeptide-1 Powder manufactured at HDM BIO?

A: At HDM BIO, the peptide is produced using advanced solid-phase peptide synthesis (SPPS) in a GMP-compliant environment. This involves sequential amino acid coupling, purification by preparative HPLC, and lyophilization. The entire process is validated to ensure batch-to-batch consistency and high chemical purity.

 

Q:What quality testing is performed on each batch?

A: Each production batch undergoes comprehensive testing including HPLC for purity (≥98%), Mass Spectrometry (MS) for identity confirmation, and tests for water content, solubility, and appearance. A full Certificate of Analysis (COA) is issued for every shipment to ensure transparency and quality.

 

Q:Where can I buy Biotinoyl Tripeptide-1 Powder in bulk?

A: Bulk quantities can be purchased directly from HDM BIO, a specialized Biotinoyl Tripeptide-1 manufacturer based in China. We supply bulk powder for cosmetic manufacturers, private-label brands, and ingredient distributors, with packaging sizes from 1g to commercial quantities, along with full technical support and documentation for global export.

 

Q:What documents are available for Biotinoyl Tripeptide-1 Powder?

A: Each batch can be supplied with a full documentation package including COA, MSDS, TDS, HPLC testing data, and MS identity confirmation reports. All documents align with international cosmetic raw material regulatory requirements to support product registration and import procedures.

 

Technical Review

 

Item

Details

Reviewed by

HDM BIO Cosmetic Peptide Manufacturing Technical Team

Last Reviewed

July 2026

Manufacturer

HDM BIO

Location

China

Standard

GMP-compliant

Reviewer Expertise

Cosmetic peptide synthesis, SPPS manufacturing, HPLC quality control, cosmetic raw material compliance

Review Scope

Technical Data, Manufacturing Processes, QC Specifications

Quality System

ISO/GMP-based management

Documentation

COA, MSDS, TDS, HPLC, MS

Category

Cosmetic Peptide Ingredient

Intended Use

Raw material for cosmetic formulation only

Disclaimer: The information provided in this document is for technical and informational purposes for cosmetic formulators and manufacturers. It does not constitute medical advice. This product is intended for use as a cosmetic ingredient and is not intended to diagnose, treat, cure, or prevent any disease.

 

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Certificates

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Shipping & Packing

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Request COA, Pricing, or Samples for Biotinoyl Tripeptide-1 Powder

 

HDM BIO supplies GMP-manufactured Biotinoyl Tripeptide-1 Powder to global cosmetic brands, contract manufacturers, and ingredient distributors. Every order includes batch-specific COA documentation, and our technical team is available to support formulation integration.

 

Request COA    Get Bulk Pricing    Request Sample

 

WhatsApp: +86 19991242181
Email:sales@hdmbio.com

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