Carbasalate Calcium API CAS 5749-67-7 | ≥98% NSAID Veterinary Pharmaceutical Manufacturer China

Key Selling Points

✓ Aspirin Calcium-Urea Complex (Water-Soluble NSAID)

✓ Rapid Hydrolysis to Acetylsalicylic Acid - COX Inhibition

✓ Fast Absorption, Quick Onset, High Bioavailability

✓ Soluble Powder Form for Drinking-Water Medication

✓ White to Off-White Powder, No Residue, Safe Profile

✓ Swine, Poultry & Livestock Fever and Pain Relief

What Is Carbasalate Calcium Powder?

Carbasalate Calcium Powder is a water-soluble aspirin calcium-urea complex, a salicylate-class non-steroidal anti-inflammatory drug widely used in veterinary medicine for the symptomatic treatment of fever, pain and inflammatory conditions in pigs, poultry and other livestock. It is the calcium salt of acetylsalicylic acid (aspirin) complexed with urea, which significantly improves water solubility compared with aspirin free acid.

After oral administration, carbasalate calcium is rapidly absorbed and hydrolyzed to acetylsalicylic acid (aspirin), which then exerts its pharmacological effects. It is valued for its fast absorption, quick onset of action, high bioavailability and favorable safety profile with no residual concerns, making it suitable for drinking-water medication in swine and poultry operations.

How Does Carbasalate Calcium Powder Work?

Carbasalate Calcium Powder acts through its active metabolite acetylsalicylic acid (aspirin), which irreversibly inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins and thromboxanes. This produces antipyretic effects by lowering the hypothalamic thermoregulatory set point, analgesic effects through both peripheral and central pain modulation, and anti-inflammatory effects through suppression of prostaglandin-mediated inflammatory mediators.

Its rapid hydrolysis to aspirin and high oral bioavailability make Carbasalate Calcium Powder a practical reference compound for veterinary fever and pain management research, particularly in species where drinking-water or feed medication is the preferred route of administration.

What Are the Applications of Carbasalate Calcium Powder?

Swine Fever & Systemic Illness: Used in formulation research for febrile diseases in pigs, including high fever of unknown origin, respiratory and systemic infections requiring symptomatic fever control.
Poultry Febrile Conditions: Evaluated for fever and pain associated with bacterial and viral infections in chickens and other poultry, administered via drinking water.
Livestock Pain & Inflammation: Studied for musculoskeletal pain, inflammatory conditions and post-procedural analgesia in cattle, sheep, horses and companion animals.
Drinking-Water Medication: The soluble powder form is ideal for flock/herd-wide administration, particularly when individual animal treatment is impractical.
Adjunctive Therapy: Used as an adjunct in infectious disease management to reduce fever and improve animal comfort while primary antimicrobial therapy takes effect.

What Is the Difference Between Carbasalate Calcium and Aspirin?

Feature	Carbasalate Calcium	Aspirin (Acetylsalicylic Acid)
CAS	5749-67-7	50-78-2
Form	Calcium-urea complex	Free acid
Molecular Formula	Ca(C₉H₇O₄)₂·CH₄N₂O	C₉H₈O₄
Molecular Weight	458.44	180.16
Water Solubility	Soluble (complexed)	Slightly soluble
Active Metabolite	Hydrolyzes to aspirin	Aspirin itself
Typical Use	Veterinary soluble powder / drinking water	Human oral tablets / veterinary feed

How Does Carbasalate Calcium Compare With Other Veterinary NSAIDs?

Feature	Carbasalate Calcium	Flunixin Meglumine	Metamizole Sodium	Meloxicam
CAS	5749-67-7	42461-84-7	68-89-3	71125-38-7
Class	Salicylate (aspirin complex)	Nicotinic acid derivative	Pyrazolone	Oxicam (COX-2 preferential)
Route	Oral (drinking water)	IV/IM	IV/IM	IV/IM/oral
Antipyretic	Strong	Strong	Strong	Moderate
Analgesic	Moderate	Strong	Strong	Moderate
Spasmolytic	No	No	Yes	No
Anti-Inflammatory	Moderate	Strong	Moderate	Strong
Primary Species	Swine, poultry	Horse, cattle, pig	Horse, cattle, pig, dog	Dog, cat, cattle

How Is Carbasalate Calcium Powder Manufactured?

Carbasalate Calcium Powder is manufactured by reacting acetylsalicylic acid (aspirin) with calcium hydroxide to form the calcium salt, followed by complexation with urea, purification, crystallization and drying.

Raw Material QC → Aspirin Starting Material → Calcium Salt Formation → Urea Complexation → Purification → Crystallization → Drying → Final QC → Packaging

HDM BIO controls key reaction, complexation, purification and drying parameters to maintain consistent purity, water solubility and batch quality.

Quality Specifications

Test Item	Standard	Typical Result
Appearance	White to off-white powder	Consistent
Assay (HPLC)	≥98%	99.0%
Identity (IR)	Conforms to reference standard	Confirmed
Calcium Content	8.5–9.0%	8.7%
Urea Content	12.5–13.5%	13.0%
Related Substances	Within specification	Pass
Loss on Drying	≤3.0%	1.2%
Residue on Ignition	Within specification	Compliant
Heavy Metals	≤10 ppm	Compliant
pH (1% solution)	4.5–7.0	5.8

What Quality Control Tests Are Performed for Carbasalate Calcium Powder?

Each batch undergoes multi-step quality control before release to verify identity, purity, calcium/urea content and physical properties.

Raw Material QC → In-Process Control → HPLC Assay → IR Identity Verification → Calcium Content (Complexometric) → Urea Content → Related Substances (HPLC) → Loss on Drying → Heavy Metals → Residue on Ignition → pH Test → Final Batch Release

Key evaluations include identification via infrared (IR) spectroscopy, HPLC active content assay, calcium content determination, urea content verification, related substances analysis, loss on drying, heavy metal limits, residue on ignition and pH verification. Every commercial batch is supported by a batch-specific COA and relevant analytical documentation for incoming QC and supplier qualification.

What Factors Affect Carbasalate Calcium Powder Bulk Price?

Carbasalate Calcium Powder bulk pricing is driven by several key factors:

Starting Material Costs: Aspirin (acetylsalicylic acid), calcium hydroxide and urea availability and pricing directly influence manufacturing expenses.
Purity & Solubility Grade: Higher assay percentages and strict water-solubility specifications for soluble powder cost more to produce.
Regulatory Compliance & Certification: GMP-standard API batches with consistent COA and complete export documentation demand a higher price.
Order Volume: Large-scale industrial or wholesale contracts receive steeper per-kilogram discounts than small-batch specialty orders.
Logistics & Geography: Shipping distance, moisture-barrier packaging requirements and customs compliance add to the landed cost.

Contact HDM BIO for a current quotation and volume-based pricing.

Why Choose HDM BIO as Your Carbasalate Calcium Powder Supplier?

High-purity (≥98% / typical 99%+) aspirin calcium-urea complex with controlled solubility
Fast-acting antipyretic analgesic suitable for drinking-water medication
GMP-aligned production, ISO & HACCP certified quality system
Full batch traceability and complete documentation (COA, MSDS, HPLC)
Flexible supply: gram samples to ton-level bulk orders
Global export to 70+ countries with full customs support

Bulk Packaging, Shipping & Storage

Packaging: Foil bags for samples and moisture-proof fiber drums for bulk orders.
Custom Packaging: OEM labeling available.
Shipping Documents: COA, MSDS/SDS, commercial invoice, packing list and customs documentation available according to order requirements.
Storage: Store tightly sealed in a cool, dry, light-protected environment. Shelf life: 24 months.
Handling: For veterinary raw material use only; not for direct clinical administration.

Frequently Asked Questions About Carbasalate Calcium Powder

Q1: What is Carbasalate Calcium Powder?

A: A water-soluble aspirin calcium-urea complex, a salicylate-class NSAID supplied as veterinary raw material for antipyretic and analgesic formulations, particularly for swine and poultry drinking-water medication.

Q2: What is the CAS number?

A: 5749-67-7.

Q3: Is Carbasalate Calcium the same as aspirin?

A: It is the calcium salt of aspirin complexed with urea. After oral administration it hydrolyzes to acetylsalicylic acid (aspirin), which is the active metabolite.

Q4: How does it work?

A: Its active metabolite aspirin irreversibly inhibits cyclooxygenase (COX), reducing prostaglandin synthesis and producing antipyretic, analgesic and anti-inflammatory effects.

Q5: Is Carbasalate Calcium water soluble?

A: Yes. The calcium-urea complex form is significantly more water-soluble than aspirin free acid, making it suitable for soluble powder and drinking-water formulations.

Q6: What documents are provided with each batch?

A: Batch-specific COA, HPLC report, IR identity records, calcium and urea content data, MSDS/SDS and relevant export documentation are available according to order requirements.

Q7: What purity do you supply?

A: Standard ≥98% HPLC; typical batch result 99%. Higher grades available on request.

Q8: Where can I buy it from China?

A: HDM BIO supplies bulk Carbasalate Calcium Powder with batch COA and global export support.

Q9: How much does Carbasalate Calcium Powder cost?

A: Bulk pricing depends on aspirin/urea starting material costs, purity/solubility grade, regulatory compliance, order volume and logistics. Contact HDM BIO for a current quotation.

Q10: Is this product for human clinical use?

A: It is supplied as veterinary raw material and is not intended for direct clinical administration. Finished products manufactured from the material must comply with applicable local regulatory requirements.