Tilmicosin Powder API

 

 

• Cattle Respiratory Disease (BRD): Used in formulation research for bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida and Mycoplasma bovis in calves and pre-ruminants.
• Swine Respiratory Disease (SRD): Evaluated for enzootic pneumonia and respiratory complications associated with Actinobacillus pleuropneumoniae and Pasteurella multocida.
• Poultry Health: Studied for chronic respiratory disease (CRD) caused by Mycoplasma gallisepticum and M. synoviae, infectious coryza and fowl cholera in chickens and turkeys.
• Metaphylaxis: Used in high-risk animal groups for preventive respiratory disease control research.
• Viral Co-Infection Research: Investigated for potential inhibitory effects on Porcine Reproductive and Respiratory Syndrome (PRRS) virus replication in alveolar macrophages.

 

Test Item	Standard	Typical Result
Appearance	White to off-white powder	Consistent
Assay (HPLC)	≥98%	99.2%
Identity (IR)	Conforms to reference standard	Confirmed
Related Substances	Within specification	Pass
Loss on Drying	≤5.0%	2.3%
Residue on Ignition	≤0.5%	Compliant
Heavy Metals	≤10 ppm	Compliant
Specific Rotation	-20° to -30°	-25°

 

 

Each batch undergoes multi-step quality control before release to verify identity, purity and physical properties.

 

Raw Material QC → In-Process Control → HPLC Assay → IR Identity Verification → Related Substances (HPLC) → Loss on Drying → Heavy Metals → Residue on Ignition → Specific Rotation → Final Batch Release

 

Key evaluations include identification via infrared (IR) spectroscopy, HPLC active content assay, related substances analysis, loss on drying, heavy metal limits, residue on ignition and specific rotation verification. Every commercial batch is supported by a batch-specific COA and relevant analytical documentation for incoming QC and supplier qualification.

 

 

Tilmicosin Powder API bulk pricing is driven by several key factors:

• Starting Material Costs: Tylosin raw material availability and pricing directly influence semi-synthetic manufacturing expenses.
• Purity & Grade Quality: Higher assay percentages and strict impurity control for specialized formulations cost more to produce.
• Regulatory Compliance & Certification: GMP-standard API batches with consistent COA and complete export documentation demand a higher price than non-certified alternatives.
• Order Volume: Large-scale industrial or wholesale contracts receive steeper per-kilogram discounts than small-batch specialty orders.
• Logistics & Geography: Shipping distance, cold-chain requirements (2–8°C storage) and customs compliance add to the landed cost.

Contact HDM BIO for a current quotation and volume-based pricing.

 

 

• High-purity (≥98% / typical 99%+) semi-synthetic macrolide with controlled impurities
• Animal-exclusive respiratory antibiotic with lung-targeting properties
• GMP-aligned production, ISO & HACCP certified quality system
• Full batch traceability and complete documentation (COA, MSDS, HPLC)
• Flexible supply: gram samples to ton-level bulk orders
• Global export to 70+ countries with full customs support

 

 

• Packaging: Foil bags for samples and moisture-proof fiber drums for bulk orders.
• Custom Packaging: OEM labeling available.
• Shipping Documents: COA, MSDS/SDS, commercial invoice, packing list and customs documentation available according to order requirements.
• Storage: Store tightly sealed in a cool, dry, light-protected environment. Shelf life: 24 months.
• Handling: For veterinary raw material use only; not for direct clinical administration.

 

 

Q1: What is Tilmicosin Powder API?

A: A semi-synthetic macrolide antibiotic derived from tylosin, designed exclusively for veterinary use and supplied as raw material for respiratory disease formulations in cattle, swine and poultry.

 

Q2: What is the CAS number?

A: 108050-54-0 (free base); tilmicosin phosphate is 137330-13-3.

 

Q3: Is Tilmicosin a macrolide antibiotic?

A: Yes. Tilmicosin is a second-generation semi-synthetic macrolide antibiotic that binds to the bacterial 50S ribosomal subunit and inhibits protein synthesis.

 

Q4: How does it work?

A: It binds to the 50S ribosomal subunit (23S rRNA), blocking peptidyl transferase and inhibiting peptide chain elongation, resulting in bacteriostatic activity.

 

Q5: What animals is it used for?

A: Primarily cattle (bovine respiratory disease), swine (enzootic pneumonia) and poultry (chronic respiratory disease caused by Mycoplasma).

 

Q6: What documents are provided with each batch?

A: Batch-specific COA, HPLC report, IR identity records, MSDS/SDS and relevant export documentation are available according to order requirements.

 

Q7: What purity do you supply?

A: Standard ≥98% HPLC; typical batch result 99%. Higher grades available on request.

 

Q8: Where can I buy it from China?

A: HDM BIO supplies bulk Tilmicosin Powder API with batch COA and global export support.

 

Q9: How much does Tilmicosin Powder API cost?

A: Bulk pricing depends on tylosin starting material costs, purity grade, regulatory compliance, order volume and cold-chain logistics. Contact HDM BIO for a current quotation.

 

Q10: Is this product for human clinical use?

A: It is supplied as veterinary raw material and is not intended for direct clinical administration. Finished products manufactured from the material must comply with applicable local regulatory requirements.

 

 

• Batch-specific COA & MSDS
• GMP & ISO Certification
• Custom Bulk Pricing
• Research Samples Available