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Acetyl Tetrapeptide-3 Powder

Acetyl Tetrapeptide-3 Powder

Appearance: White to off white powder
Specification: 98% min
CAS Number: 827306-88-7
Molecular Formula: C22H39N9O5
Molecular Weight: 509.6
EINECS: 1308068-626-2
Shelf Life: 2 Years Proper Storage
Stock: Fresh Stock
Certificate: COA,GMP,ISO,HACCP
Service: OEM&ODM Service

Product Introduction

Acetyl Tetrapeptide-3 Powder | High Purity Cosmetic Peptide Manufacturer & Bulk Supplier

Core Selling Points

✔ Cosmetic Grade ≥98% HPLC Verified

✔ Batch-Specific COA Available

✔ GMP & ISO Certified Production

✔ Stable Bulk Supply & Flexible MOQ

✔ Custom OEM & ODM Peptide Support

✔ Global Door-to-Door Shipping

✔ Free Samples for Formulator Testing

 

What Is Acetyl Tetrapeptide-3 Powder?

 

HDM BIO is a professional Acetyl Tetrapeptide-3 Powder manufacturer supplying bulk powder for global hair care brands, scalp care formulators, and private-label manufacturers.

 

As a biomimetic acetylated tetrapeptide, Acetyl Tetrapeptide-3 Powder is widely adopted in scalp health and hair retention cosmetic formulations. Produced via controlled solid-phase peptide synthesis under GMP standards, the N-terminal acetyl modification improves scalp tissue affinity and formulation stability, performing well in aqueous hair tonics, serums and shampoo bases.

 

This ingredient supports hair follicle extracellular matrix structure and strengthens hair anchoring, with a mild scalp-friendly profile. As an experienced bulk Acetyl Tetrapeptide-3 Powder supplier, HDM BIO provides full HPLC and MS identity verification reports with every shipment to satisfy global cosmetic registration and import compliance requirements.

 

What Are the Official Quality Specifications of Acetyl Tetrapeptide-3 Powder?

 

Every production batch of Acetyl Tetrapeptide-3 Powder undergoes rigorous analytical testing at HDM BIO's QC laboratory, with unique batch COA issued for all bulk orders.

 

Item

Specification

Result

Appearance

White to off white powder

Consistent

Purity(HPLC)

≥98%

99.28%

MS

Consistent

Consistent

Conclusion

The product complies with the requirements

 

Why Do Formulators Choose Acetyl Tetrapeptide-3 Powder?

 

  • Supports hair follicle ECM integrity and improves hair root anchoring for hair retention and scalp care formulations
  • Acetylated molecular structure delivers enhanced scalp affinity and long-term formula stability
  • Mild, non-irritating profile compatible with sensitive scalp and lash & eyebrow formulations
  • Rising demand for follicle-targeted clean beauty actives drives widespread adoption in premium hair lines
  • Consistent batch purity ≥98% enables reliable mass production of salon and retail hair care products
  • Full regulatory documentation available to support global brand registration and OEM development

 

How Does Acetyl Tetrapeptide-3 Powder Compare with Other Popular Hair Care Peptides?

 

Ingredient

Primary Benefit

Water Solubility

Typical Applications

Acetyl Tetrapeptide-3

Supports hair follicle ECM & hair root anchoring

Excellent

Hair thinning scalp serums, scalp tonics, brow & lash formulas

Biotinoyl Tripeptide-1

Nourishes follicles, supports lash & eyebrow appearance

Good

Eyelash serums, nourishing shampoos

Copper Tripeptide-1 (GHK-Cu)

Scalp conditioning, tissue microcirculation support

Excellent

Multi-purpose scalp repair hair care

Redensyl Complex

Multi-target follicle support complex

Excellent

Professional hair density scalp concentrates

 

Which Hair Care Products Commonly Use Acetyl Tetrapeptide-3 Powder?

 

  • Hair thinning scalp serums – Core active for professional follicle strengthening and hair density support cares
  • Scalp revitalizing tonics – Daily scalp care for improving hair retention and reducing excessive hair shedding
  • Eyelash & eyebrow serums – Gentle peptide for lash and brow thickening & density enhancement formulations
  • Functional shampoos & conditioners – Mild daily hair care lines for balanced scalp health and sustained hair vitality
  • Post-procedure scalp recovery products – Calming care after salon scalp cares to protect fragile scalp and hair follicles
  • Private-label scalp & hair density collections – Custom OEM wholesale hair care formulas for premium clean beauty lines

 

How Is Acetyl Tetrapeptide-3 Powder Manufactured & Quality Controlled?

 

Production Workflow

Raw Material Inspection → Fmoc SPPS Sequential Coupling → N-terminal Acetylation Modification → Resin Cleavage & Side-Chain Deprotection → Preparative HPLC Purification → Vacuum Lyophilization → Finished Product QC Testing → Batch COA Issuance → Sealed Protective Packaging

 

QC Inspection Workflow

Incoming Raw Material QC → In-process Production Monitoring → HPLC Purity Testing → Mass Spectrometry Identity Verification → Moisture Content & Heavy Metal Testing → Final Batch Release Approval

 

Key Process Highlights

All synthesis steps run inside GMP-compliant clean workshops. Every raw material carries complete traceability records, and multi-stage purification ensures stable ≥98% purity. Finished Acetyl Tetrapeptide-3 Powder is vacuum-packed to preserve peptide activity during long-distance global shipping.

 

How Can Formulators Maximize the Performance of Acetyl Tetrapeptide-3 Powder?

 

 

  • Compatible ingredients: Excellent synergy with Biotinoyl Tripeptide-1, hyaluronic acid and niacinamide for multi-functional scalp and hair density formulations
  • Recommended pH: Maintain pH 5.0 – 7.0 to retain optimal Acetyl Tetrapeptide-3 Powder bioactivity
  • Addition timing: Add during cooling phase below 45°C after emulsification to avoid peptide inactivation
  • Avoid prolonged heating: High-temperature sustained processing may impact long-term formulation stability
  • Finished goods storage: Seal finished products away from direct light; refrigeration extends shelf life and peptide activity

 

Why Do Global Hair Care Brands Choose HDM BIO?

 

 

  • 10+ Years professional cosmetic peptide manufacturing experience
  • Full batch traceability for every Acetyl Tetrapeptide-3 Powder production lot
  • Complete GMP closed production workshops
  • Exports to more than 70 countries & regions worldwide
  • ISO & HACCP dual certified quality management system
  • Dedicated cosmetic formulation technical team support
  • Flexible sample trial and large bulk OEM & ODM orders
  • Fast global air & sea logistics for stable delivery

 

What Are the Most Frequently Asked Questions About Acetyl Tetrapeptide-3 Powder?

 

Q1: What is Acetyl Tetrapeptide-3 Powder used for in cosmetics?

A: It is a cosmetic peptide active mainly applied in scalp care, hair retention serums and eyelash/eyebrow formulations. It helps support healthy follicle conditions and strengthens hair root anchoring to improve overall hair vitality.

 

Q2: Is Acetyl Tetrapeptide-3 Powder water-soluble?

A: Yes, it has good water solubility, easy to incorporate into water-based scalp tonics, serums and mild shampoo systems.

 

Q3: Can Acetyl Tetrapeptide-3 Powder Be Used in Leave-on Hair Serums?

A: Yes, Acetyl Tetrapeptide-3 Powder is widely formulated in leave-on scalp and hair serums. Its mild profile and stable performance make it ideal for long-contact scalp care products.

 

Q4: Can Acetyl Tetrapeptide-3 Powder be combined with Biotinoyl Tripeptide-1?

A: Yes, they show excellent compatibility. This peptide combination is widely used in commercial hair retention and lash care formulations.

 

Q5: What documents are available for bulk Acetyl Tetrapeptide-3 Powder orders?

A: Each batch includes COA, MSDS, TDS, HPLC chromatogram and mass spectrum reports, supporting overseas cosmetic registration and customs clearance.

 

Q6: Where can I buy bulk Acetyl Tetrapeptide-3 Powder?

A: Bulk Acetyl Tetrapeptide-3 Powder can be purchased directly from HDM BIO, a professional China GMP peptide factory. We provide free samples, flexible bulk pricing and full technical guidance for global wholesale buyers.

 

What Is the Technical & Compliance Review for This Peptide?

 

  • Reviewed by: HDM BIO Cosmetic Peptide Manufacturing Technical Team

  • Last Reviewed: July 2026

  • Manufacturer: HDM BIO

  • Location: China

  • Standard: GMP, ISO, HACCP

  • Expertise: Solid-phase peptide synthesis, cosmetic peptide modification, HPLC purification, QC systems, GMP compliance

  • Review Scope: Process validation, specification review, and quality documentation

  • Quality System: Full GMP-compliant manufacturing and testing environment Documentation: Batch-specific COA, MSDS and specification data provided

  • Category: Cosmetic peptide ingredient

  • Intended Use: Cosmetic raw material for topical skincare formulations

    This product is a cosmetic ingredient intended for topical hair and scalp formulations only. It shall not be used for pharmaceutical drugs, oral health supplements or injectable preparations. All page content is for B2B raw material procurement reference only. Formulators need to complete independent compatibility and stability testing before mass production.

 

What Related Cosmetic Peptides for Hair & Scalp Care?

 

  • Biotinoyl Tripeptide-1 Powder
  • GHK-Cu Powder
  • Palmitoyl Tripeptide-8 Powder
  • Acetyl Tetrapeptide-40 Powder
  • Caprooyl Tetrapeptide-3 Powder
  • Acetyl Hexapeptide-8 Powder

 

What Technical Resources Help Formulators Use This Peptide Better?

 

  • How Does Acetyl Tetrapeptide-3 Support Scalp & Follicle Health?
  • How Are Cosmetic Hair Peptides Manufactured?
  • Which Hair Care Peptides Are Best for Modern Scalp Formulations?

 

factory

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Certificates

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Shipping & Packing

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How to Get  Acetyl Tetrapeptide-3 Powder COA, Samples & Bulk Pricing?

 

We provide full support for global skincare brands and formulators:

✔ Batch-specific COA

✔ MSDS Safety Data Sheet

✔ GMP Certification Documents

✔ Custom Bulk Pricing

✔ Free Samples Available

✔ Dedicated Technical Support

 

Request COA ; Get Bulk Pricing; Request Sample

 

WhatsApp: +86 19991242181 

Email:sales@hdmbio.com

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