Eptifibatide Acetate Powder

Eptifibatide Acetate Powder Manufacturer China | GMP Antiplatelet Peptide API Supplier CAS 148031-34-9

Core Selling Points

✅ Manufactured under GMP-aligned quality system for cyclic peptide API production

✅ ≥98% HPLC Purity & Full amino acid sequence verified by LC-MS

✅ Batch-Specific COA & Complete production traceability documentation

✅ Global export service with full customs and regulatory support

✅ Custom cyclic peptide synthesis & lyophilization OEM service

Eptifibatide Acetate powder is a synthetic cyclic heptapeptide API intermediate that acts as a selective glycoprotein IIb/IIIa receptor antagonist. As a specialized cardiovascular research peptide, it is widely used in antiplatelet pharmacology research, thrombosis mechanism studies and novel cardiovascular peptide drug R&D pipelines.

Produced with optimized Fmoc solid-phase peptide synthesis, directional cyclization and multi-stage gradient HPLC purification, our Eptifibatide Acetate API delivers intact cyclic peptide structure, stable biological characteristics and consistent batch quality. HDM BIO serves global biotech research teams and pharmaceutical manufacturers with one-stop bulk supply, custom peptide modification and professional technical support. This product is for R&D and manufacturing use only, not for direct clinical administration.

Every production batch of Eptifibatide undergoes rigorous dual QC testing (HPLC + LC-MS) in HDM BIO's in-house laboratory, with an exclusive batch COA issued for all bulk procurement orders.

Driven by sustained growth in global cardiovascular drug development and peptide therapeutics R&D investment, demand for high-purity antiplatelet peptide APIs has maintained steady year-on-year growth since 2024.

The global peptide therapeutics market continues to expand at an annual growth rate of over 7%, with cardiovascular peptide pipelines accounting for a growing share. As a classic GP IIb/IIIa antagonist reference compound, Eptifibatide is a core raw material for thrombosis mechanism research and antiplatelet drug development. The growing number of biotech pipelines targeting thrombotic disease regulation has directly driven increased bulk procurement demand for high-purity Eptifibatide API.

Meanwhile, stricter quality standards for peptide API intermediates in global pharmaceutical R&D have pushed buyers to prioritize manufacturers with complete quality documentation and traceable production systems, replacing low-quality uncertified suppliers in the market.

When sourcing Eptifibatide API powder, pharmaceutical R&D teams and peptide manufacturers should evaluate five core factors to ensure product quality and supply stability:

• HPLC purity verification: Confirm ≥98% purity with official chromatogram and impurity profile data
• LC-MS sequence confirmation: Verify full-length cyclic peptide structure to avoid truncated impurities
• Batch-specific COA availability: Ensure every production batch comes with complete quality documentation
• Stable cyclic peptide manufacturing capacity: Verify technical capability to avoid delivery delays
• Export documentation and technical support: Confirm full regulatory document support and application guidance

HDM BIO provides pharmaceutical-grade Eptifibatide Acetate with complete quality documentation, flexible MOQ and global shipping support for lab research batches and large-scale production orders.

As a 7-amino-acid cyclic peptide with a disulfide bond structure, Eptifibatide has high technical barriers in industrial synthesis and purification, which is the core threshold separating professional peptide manufacturers from low-quality suppliers.

Key production challenges include:

• Precise control of directional disulfide bond cyclization to reduce mismatched by-products
• High risk of incomplete coupling and truncated sequence impurities during chain assembly
• Difficulty in separating cyclic target peptide from linear and mismatched cyclic impurities
• Strict full-structure verification and molecular weight confirmation standards
• High requirements for batch stability and activity consistency

HDM BIO applies optimized cyclization monitoring technology, multi-stage gradient HPLC purification and full-process LC-MS confirmation for every batch, effectively reducing by-products and ensuring verified full-length cyclic peptide sequence consistency and stable batch quality.

As a selective glycoprotein IIb/IIIa receptor antagonist, Eptifibatide binds competitively to platelet GP IIb/IIIa receptors, blocking fibrinogen cross-linking and inhibiting platelet aggregation. It provides a well-established experimental model for studying thrombosis mechanisms and antiplatelet drug efficacy evaluation.

This peptide is widely studied as a research tool for cardiovascular pharmacology and thrombotic disease mechanism investigation. It serves as a core reference compound for antiplatelet drug development and hematology research worldwide, supporting academic exploration and new drug precursor development.

Different cardiovascular-targeted peptides have different mechanisms and R&D application scenarios. The comparison below helps R&D teams select the right raw material based on project positioning:

For broader cardiovascular pharmacology research projects, Eptifibatide can also be used alongside Cetrorelix Acetate and other peptide API references as control materials for mechanism studies.

Eptifibatide is produced through Fmoc solid-phase peptide synthesis, with specialized directional disulfide bond cyclization and multi-stage purification processes. Precise control of cyclization efficiency and structural integrity is the core technical barrier to ensure high-purity cyclic peptide.

For a detailed step-by-step breakdown of production and QC workflows, read our dedicated guide: How Is Eptifibatide Peptide Manufactured? Full SPPS & Cyclization Process Explained

Complete Eptifibatide Manufacturing Workflow

Raw Material Inspection → Linear Peptide SPPS Coupling → Resin Cleavage & Deprotection → Directional Disulfide Bond Cyclization → Multi-stage HPLC Purification → Acetate Salt Formation → Vacuum Lyophilization → QC Testing → Batch COA Issuance → Sealed Light-Proof Pharmaceutical Packaging

QC Inspection Workflow

Incoming Raw Material QC → In-process Coupling & Cyclization Monitoring → HPLC Purity Testing → Mass Spectrometry Identity & Structure Verification → Moisture & Heavy Metal Testing → Residual Solvent Detection → Final Batch Release Approval

Core Process Highlights

Optimized directional cyclization technology effectively reduces mismatched disulfide bond by-products

Multi-stage high-precision HPLC purification thoroughly removes linear and structural analog impurities

Full-structure LC-MS verification ensures verified intact cyclic peptide chain

Vacuum lyophilization and light-proof sealed packaging effectively maintain peptide stability during transportation and low-temperature storage

Before purchasing Eptifibatide API, pharmaceutical R&D and procurement teams should verify the following items to ensure product quality meets project standards:

✓ Official HPLC purity chromatogram with full impurity profile

✓ LC-MS molecular weight verification report

✓ Cyclic peptide structure confirmation data

✓ Batch-specific Certificate of Analysis (COA)

✓ Peptide stability data and storage guideline documentation

✓ Complete manufacturing batch traceability records

✓ Full set of export customs and regulatory documentation

Not all peptide suppliers have the technical capability to produce high-quality cyclic peptides like Eptifibatide. Use the table below to evaluate and screen qualified manufacturers:

Suppliers that cannot provide complete batch test data or independent production capacity verification carry high risks of product quality inconsistency and supply disruption.

1. Cardiovascular pharmacology research: Platelet aggregation mechanism and thrombosis pathway experiments
2. Pharmaceutical R&D intermediate: Raw material for novel antiplatelet drug preliminary development
3. Biomedical reagent preparation: Laboratory reference standards and experimental control reagents
4. Peptide formulation research: Injectable peptide formulation and delivery system development
5. Hematological disorder mechanism research: Thrombotic disease regulation pathway studies

Professional pharmaceutical buyers and R&D institutions should verify the following core indicators before procurement to avoid unstable experimental data and supply risks:

• Authentic batch-specific COA with complete quality test data
• Official HPLC purity chromatogram and detailed related substance analysis
• LC-MS molecular identity confirmation and cyclic structure verification report
• Full production traceability records from raw materials to finished product
• Standard low-temperature light-proof packaging conditions
• Stable cyclic peptide production capacity for long-term project cooperation
• Complete export documents and cross-border logistics support
• Technical support for peptide dissolution and experimental application guidance

China has become a global core manufacturing base for high-end cyclic peptide APIs in recent years, with a mature and cost-effective Fmoc SPPS industrial system, advanced cyclization technology and complete peptide quality inspection systems. Compared with overseas suppliers, Chinese peptide manufacturers have obvious advantages in cyclic peptide synthesis yield, batch stability and customized service flexibility.

As a professional China Eptifibatide API supplier, HDM BIO focuses on cyclic peptide R&D and production, solves the technical pain points of disulfide bond mismatches and low cyclization yield, and provides global customers with high-quality Eptifibatide Acetate powder with complete quality documents, flexible sample and bulk supply, and one-stop customized peptide synthesis services.

The bulk quotation of Eptifibatide API depends on multiple procurement conditions, with no fixed universal price. The following are the core factors affecting final bulk pricing:

HDM BIO provides tiered bulk pricing policies, supporting milligram-level exploratory experiment samples, medium-batch continuous research supply and large-scale bulk wholesale. Custom peptide synthesis service is available upon request. Contact our sales team for the latest real-time quotation and production lead time.

• 10+ years of professional cyclic peptide API manufacturing experience in China
• Mature optimized Fmoc SPPS production line with directional cyclization technology
• Certified quality management system with ISO & HACCP compliance
• Strict full-structure verification and batch stability control
• Full traceability for every Eptifibatide production batch
• Flexible supply: gram-level lab samples to kilogram-level bulk API orders
• Global export service covering 70+ countries and regions
• Professional technical team supporting cardiovascular pharmacology research consulting

Q: Where can I buy Eptifibatide API powder from China?

A: HDM BIO is a China-based GMP-aligned Eptifibatide API manufacturer supplying high-purity peptide powder to global pharmaceutical R&D teams and biotech companies. We support small research samples to large bulk orders, with complete export documentation and worldwide shipping.

Q: What documents should an Eptifibatide supplier provide?

A: A qualified supplier should provide batch-specific COA, HPLC purity chromatogram, LC-MS identity verification report, MSDS, ISO/HACCP certification, and full production traceability records to support global customs clearance and quality audit.

Q: How is Eptifibatide API purity verified?

A: Eptifibatide purity is primarily verified via High Performance Liquid Chromatography (HPLC) to quantify target peptide content and impurity levels. Mass spectrometry (LC-MS) is further used to confirm molecular weight and cyclic peptide structural integrity.

Q: Where can I buy Eptifibatide API powder in bulk?

A: HDM BIO supplies bulk Eptifibatide API powder for pharmaceutical manufacturers, biotech labs and research institutions, with complete COA, HPLC reports and global export support. We serve clients from R&D trial batches to large-scale annual supply contracts.

Q: How to verify Eptifibatide peptide quality?

A: The three core verification methods are: 1) Check HPLC purity data to confirm it meets ≥98% standards; 2) Verify molecular identity and cyclic structure via LC-MS report; 3) Review batch-specific COA covering all quality indicators.

Q: What is the CAS number of Eptifibatide Acetate?

A: The CAS registry number is 148031-34-9.

Q: What purity grades of Eptifibatide powder do you offer?

A: Standard pharmaceutical grade is ≥98% HPLC purity. Higher purity specifications (≥99%) can be customized for special research needs.

Q: Is Eptifibatide an agonist or antagonist?

A: Eptifibatide is a selective glycoprotein IIb/IIIa receptor antagonist, used as a reference material for cardiovascular pharmacology and antiplatelet research.

Q: How should Eptifibatide lyophilized powder be stored?

A: Store sealed at -20°C, protected from light and moisture. Avoid repeated freeze-thaw cycles to maintain peptide stability and activity.

Q: Does HDM BIO provide custom Eptifibatide peptide synthesis?

A: Yes. We support custom purity specifications, salt forms, packaging specifications and modified peptide synthesis services.

Q: Can I get Eptifibatide samples before placing a bulk order?

A: Yes. We provide milligram to gram-level trial samples with complete COA and test documents for research evaluation before bulk cooperation.

Q: What is the MOQ for Eptifibatide bulk powder?

A: MOQ is flexible based on purity grade and packaging requirements. We support small research batches and large bulk orders to meet different project needs.

Q: How many amino acids does Eptifibatide contain?

A: Eptifibatide is a synthetic cyclic heptapeptide containing 7 amino acid residues with an intramolecular disulfide bond.

We provide one-stop full-service support for global Eptifibatide Acetate powder bulk procurement and biopharmaceutical R&D projects:

✅ Free batch-specific COA, HPLC & LC-MS test reports

✅ MSDS safety data sheet and full GMP/ISO export certification documents

✅ Custom bulk API tiered wholesale pricing & flexible MOQ support

✅ Free pharmaceutical R&D sample application service

✅ Professional PLG analog peptide & CNS research technical support

Request COA     Get Bulk Pricing    Request Sample

WhatsApp: +86 19991242181

Email: sales@hdmbio.com

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