Gonadorelin Acetate API CAS 34973-08-5 | High Purity GnRH Decapeptide Supplier China
Core Selling Points
✓ ≥98% HPLC Purity
✓ LC-MS Full Decapeptide Sequence Verification
✓ Batch-Specific COA Available
✓ GMP-Aligned Production System
✓ Global Export Regulatory Support
✓ Custom Peptide Synthesis Service
What Is Gonadorelin Acetate Powder & Its Research Applications?
Gonadorelin Acetate powder is a synthetic decapeptide identical to endogenous human GnRH (LHRH), acting as a natural GnRH receptor agonist. It activates GnRH receptor signaling pathways in laboratory research models related to reproductive hormone regulation, making it the core standard raw material for HPG axis mechanism research.
Produced via optimized Fmoc solid-phase peptide synthesis and multi-stage gradient HPLC purification, our Gonadorelin Acetate API retains complete native decapeptide sequence, stable biological activity and consistent batch-to-batch performance. This product is strictly for laboratory and pharmaceutical preclinical R&D use only, not for direct human or clinical administration.
What Are the Official Quality Standards for Gonadorelin Acetate?
Every production batch of Gonadorelin Acetate undergoes dual strict QC testing (HPLC + LC-MS) in HDM BIO's in-house analytical laboratory to guarantee intact decapeptide structure and high research-grade purity.
|
Item |
Specification |
Result |
|
Appearance |
White to off-white powder |
Consistent |
|
Purity (HPLC) |
≥98% |
99.60% |
|
MS Identity |
Consistent with reference standard |
Confirmed |
|
Conclusion |
Cosmetic raw material requirement |
Passed |
What Should You Check When Buying Gonadorelin Acetate?
When sourcing Gonadorelin Acetate powder for reproductive pharmacology labs and pharmaceutical R&D teams, verify these 5 core standards to avoid truncated peptide impurities affecting experimental data:
- Full decapeptide LC-MS sequence confirmation (not just nominal molecular weight)
- HPLC chromatogram with complete single & total impurity quantification
- Independent batch COA with full production traceability logs
- Mature long-chain decapeptide SPPS synthesis production capacity
- Complete export compliance documents for cross-border laboratory procurement
What Makes Gonadorelin Acetate a High-Precision Synthetic Peptide?
Gonadorelin is a 10-residue linear decapeptide with strict coupling technical requirements. Missing amino acid fragments during synthesis will severely reduce GnRH receptor binding activity and skew HPG axis research results.
Core manufacturing challenges include sequential stepwise coupling monitoring to eliminate deletion impurities, multi-stage purification to separate truncated side products, and lyophilization parameter control to preserve native peptide bioactivity. HDM BIO adopts dedicated long-chain SPPS workflow and multi-gradient HPLC purification, with full LC-MS batch validation to ensure uniform decapeptide quality across lots.
How Does Gonadorelin Acetate Work in Pharmacological Research?
Gonadorelin Acetate powder is native GnRH decapeptide agonist, activating GnRH receptor signaling for hypothalamic-pituitary-gonadal axis basic research and fertility drug preclinical studies.
As the human endogenous gonadotropin-releasing hormone equivalent, Gonadorelin binds to pituitary GnRHR receptors to initiate intracellular cAMP signaling cascades. Experimental studies use different exposure patterns to investigate GnRH receptor signaling regulation and downstream hormone-related pathways, which are widely adopted for reproductive endocrinology, infertility mechanism and veterinary ovulation synchronization research. All descriptions are limited to in vitro and animal laboratory experiments only.
How Does Gonadorelin Compare to Other GnRH Related Peptides?
Explore our full GnRH Peptide API Comparison Guide for detailed side-by-side analysis of all agonist and antagonist raw materials. Our complete GnRH peptide API portfolio includes Gonadorelin Acetate, Ganirelix, Cetrorelix, Leuprorelin for comprehensive reproductive research solutions.
| Ingredient | Mechanism Type | Core R&D Application | CAS Number |
|---|---|---|---|
| Gonadorelin Acetate | Native GnRH decapeptide agonist (pulsatile stimulatory effect) | Endogenous HPG axis baseline research, fertility mechanism study | 34973-08-5 |
| Ganirelix | Second-generation GnRH competitive antagonist | IVF premature LH surge suppression research | 123246-29-7 |
| Cetrorelix | Long-acting GnRH antagonist | Gynecological oncology & reproductive inhibition study | 145672-81-7 |
| Leuprorelin | Modified long-acting GnRH agonist | Chronic gonadal downregulation preclinical testing | 53714-56-0 |
What Is the Price of Gonadorelin Acetate API?
The bulk price of Gonadorelin Acetate API depends on purity requirement, order quantity, packaging specification and additional testing requirements. Laboratory trial samples, medium R&D batches and kilogram-scale industrial procurement follow different tiered pricing structures. Larger order volumes correspond to lower unit costs, and custom high-purity grades or third-party testing services will increase overall cost. Contact our sales team for a customized quotation matching your exact procurement needs.
What Factors Affect Gonadorelin Acetate Bulk Pricing?
- Custom ≥99% ultra-high purity grade raises synthesis & purification cost
- Larger bulk orders enjoy tiered volume discount pricing
- Third-party full sequence testing adds service fees
- Cold-chain low-temperature shipping increases logistics expense
- Special custom peptide modification requests impact quotation
HDM BIO offers flexible pricing for lab samples, medium R&D batches and kilogram industrial orders. Contact sales team for real-time customized quotation.
Why Choose HDM BIO As Your Gonadorelin Acetate Supplier?
- 10+ years specialized GnRH decapeptide R&D & manufacturing experience in China
- ISO & HACCP certified GMP standard clean production workshops
- Mandatory LC-MS full decapeptide sequence verification for every single batch
- Flexible supply covering micro samples to ton-level industrial bulk orders
- Global service for 70+ countries with dedicated reproductive peptide technical support
What Are Common Questions About Gonadorelin Acetate?
Q1: What is the CAS number of Gonadorelin Acetate?
A: The official CAS registry number of Gonadorelin Acetate powder is 34973-08-5.
Q2: Is Gonadorelin Acetate identical to human native GnRH?
A: Yes, its 10-amino-acid decapeptide sequence completely matches endogenous human gonadotropin-releasing hormone, making it the gold standard for HPG axis baseline research.
Q3: What purity grades can you provide?
A: Standard ≥98% HPLC research grade; customized ≥99% high-purity specifications available upon request.
Q4: How to store Gonadorelin Acetate lyophilized powder?
A: Seal tightly, store at -20°C protected from light and moisture; avoid repeated freeze-thaw cycles to retain intact bioactivity.
Q5: Can I get trial samples before bulk cooperation?
A: Yes, we provide samples with full batch test documents for pre-research evaluation.
Q6: What complete documents will be delivered with orders?
A: Batch-specific COA, original HPLC chromatogram, LC-MS full sequence report, MSDS and all export certification files.
Q7: Is this peptide usable for human clinical injection?
A: No, this raw material is only for laboratory biochemical and preclinical pharmaceutical research, prohibited for direct human or veterinary clinical administration.
Q8: Do you support custom peptide sequence modification?
A: We provide customized synthesis for modified GnRH analogs and custom purity / packaging specifications.
Q9: What is the shelf life under standard storage?
A: 24 months when sealed, dry and stored at constant -20°C.
Q10: What is the molecular weight of Gonadorelin Acetate?
A: The molecular weight of Gonadorelin Acetate is 1242.37 Da.
Q11: Is Gonadorelin Acetate a peptide API?
A: Yes, Gonadorelin Acetate is a synthetic decapeptide API raw material based on the native GnRH sequence, designed for pharmaceutical R&D and laboratory research use.
Who Reviews Gonadorelin Acetate Technical Content & Quality Standards?
Scientific Content Review
Reviewed by: HDM BIO Peptide Chemistry Technical Team Expertise: Fmoc long decapeptide synthesis process development HPLC gradient purification optimization LC-MS full peptide sequence identification GMP peptide raw material quality management
Review Scope: Decapeptide sequence authenticity, SPPS manufacturing validation, HPLC/LC-MS testing compliance, reproductive research application rationality Last Updated: August 2026 Manufacturer: HDM BIO Location: China Quality Standards: GMP-aligned production, ISO & HACCP certified quality management Intended Use: Pharmaceutical & lab research intermediate only; not for human/animal clinical administration
Important Regulatory Notice
Gonadorelin Acetate powder is research-grade peptide raw material. All sales are limited to global scientific research institutions and pharmaceutical R&D companies. Buyers must comply with local chemical & pharmaceutical regulatory laws. All page content serves only B2 raw material procurement reference.
What Related Technical Resources Are Available?
- Native GnRH Decapeptide Synthesis Technical Guide
- Reproductive Endocrinology Peptide Research Handbook
- How To Source Qualified Peptide API Manufacturers In China
Factory
Certificate
Shipping & Packing
How to Request Gonadorelin Acetate COA, Samples & Bulk Quotation?
We provide full one-stop support for global pharmaceutical enterprises, research institutions and biological laboratories sourcing Gonadorelin Acetate powder:
- Batch-specific COA
- MSDS Safety Data Sheet
- GMP & ISO Certification Documents
- Custom Bulk Wholesale Pricing
- Free Samples Available
- Dedicated Technical Formulation Support
Request COA Get Bulk Pricing Request Sample
WhatsApp: +86 19991242181
Email: sales@hdmbio.com
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