Hexarelin API Manufacturer China | High Purity Synthetic Hexapeptide Raw Material Supplier CAS 140703-51-1
Core Selling Points
✓ Batch Specific COA & HPLC/LC-MS Original Spectrogram Reports
✓ Full Set Export Compliance Documents for Global Customs Clearance
✓ Flexible MOQ & Tiered Bulk Volume Discounts
✓ Professional R&D Technical Support for Laboratory Research
What Is Hexarelin API & Its Core Research Value?
Hexarelin Powder(also named Examorelin) is a synthetic six-amino-acid modified hexapeptide classified as Growth Hormone Secretagogue (GHRP). Distinct from ordinary linear GHRP peptides, its D-2-methyl tryptophan modified structure enhances anti-enzymatic degradation stability and unique dual receptor binding characteristics, making it an irreplaceable standard reference raw material for endocrine, cardiovascular and metabolic mechanism research worldwide.
Manufactured via regulated stepwise SPPS synthesis plus multi-stage gradient reverse-phase HPLC purification, our Hexarelin API maintains 100% consistent amino acid sequence across all batches, without incomplete coupling fragments or racemic impurities. This peptide raw material is exclusively applied in preclinical cell/tissue model experiments, growth hormone signal pathway exploration and cardioprotective compound screening research. It is not approved for direct human injection or clinical disease therapy.
What Are the Technical Specifications of Hexarelin API?
Every production batch of Hexarelin undergoes comprehensive QC testing in HDM BIO's independent analytical laboratory, ensuring stable composition and high purity for academic and pharmaceutical R&D projects.
|
Item |
Specification |
Result |
|
Appearance |
White to off-white powder |
Consistent |
|
Purity (HPLC) |
≥98% |
99.96% |
|
MS Identity |
Consistent with reference standard |
Confirmed |
|
Conclusion |
Cosmetic raw material requirement |
Passed |
What Are Its Core Structural Advantages?
- Modified D-2-methyl-Trp residue improves enzymatic hydrolysis resistance, longer experimental half-life in in-vitro systems
- Multi-cycle RP-HPLC purification thoroughly removes truncated peptide by-products and racemic impurities
- Lyophilized powder form enhances long-term storage stability and convenient reconstitution for laboratory buffer preparation
- Each batch attaches complete LC-MS sequence mapping report to eliminate experimental data deviation risks caused by raw material inconsistency
What Research Scenarios Apply Hexarelin API?
Hexarelin lyophilized powder is widely adopted in preclinical biochemistry laboratories globally, covering core research directions as below:
- Pituitary growth hormone secretion mechanism research: Build in-vitro pituitary cell models to study GHS-R1a receptor activation and GH pulse release pathways
- Cardioprotective signaling pathway exploration: Research CD36 scavenger receptor binding activity, myocardial ischemia-reperfusion injury and cardiac anti-fibrosis mechanisms
- Endocrine metabolism regulation research: Comparative analysis of GH, cortisol and prolactin secretion changes induced by different GHRP peptides
- Peptide stability & pharmacokinetic experimental research: Evaluate peptide degradation rate and tissue distribution in animal preclinical models
- Novel metabolic drug preclinical screening: Serve as positive control standard reagent for GH secretagogue candidate compound efficacy testing
- Academic basic research: Core raw material for endocrinology, cardiovascular and peptide biochemistry university laboratory projects
How Does Hexarelin Compare With Other Common GHRP Research Peptides?
Different growth hormone releasing peptides carry distinct structural modifications and research orientation differences. Explore our full GHRP peptide portfolio: Hexarelin, GHRP-6, Ipamorelin, GHRP-2 for multi-dimensional endocrine research solutions.
| Peptide Name | Structural Feature | Core Laboratory R&D Usage | CAS Number |
|---|---|---|---|
| Hexarelin (Examorelin) | Methylated modified hexapeptide, dual GHS-R/CD36 binding | GH secretion + cardiac protection dual-mechanism research | 140703-51-1 |
| GHRP-6 | Unmodified hexapeptide | General GH release & appetite regulation model research | 87616-84-0 |
| Ipamorelin | Highly selective pentapeptide | Pure GH-specific stimulation, low cortisol interference experiments | 170851-70-4 |
| GHRP-2 | Short-chain unmodified peptide | Basic GH secretagogue low-dose comparative screening | 158861-67-7 |
How Is Hexarelin API Produced & Full QC Controlled?
We adopt mature Fmoc solid-phase peptide synthesis (SPPS) proprietary technology for Hexarelin manufacturing, paired with full-process SOP standardized quality management. The complete production workflow includes six standardized core phases:
- Amino Acid Raw Material Validation: Test purity, optical activity and moisture of His, D-2-Me-Trp, Ala, Trp, D-Phe, Lys monomer raw materials before synthesis
- Sequential Solid-Phase Coupling Synthesis: Start from C-terminal lysine residue, complete six-step amino acid chain elongation, monitor coupling completion rate after each circulation to reduce missing sequence impurities
- TFA Cleavage & Crude Peptide Harvest: Remove all side-chain protecting groups and cleave full-length peptide from Wang resin; collect crude peptide via cold ether precipitation and vacuum drying
- Multi-Stage Gradient HPLC Purification: Separate incomplete coupling fragments and racemic isomers, collect high-purity target peptide fractions according to HPLC peak detection
- Aseptic Filtration & Programmed Lyophilization: Filter qualified peptide solution through 0.22μm sterile membrane, low-temperature freeze-drying to form uniform loose white powder
- Full-Item QC Inspection & Batch Release: Finished powder enters independent QC lab for complete testing; only batches passing all specifications can be released with full official test documents
What Should You Verify When Purchasing Goserelin Acetate API?
Modified long-acting GnRH peptides have high technical barriers. When sourcing Goserelin Acetate powder, confirm the following 5 key standards to prevent unqualified modified sequences and substandard purity from affecting R&D data:
1. LC-MS full modified structure verification report (focus on D-Ser(But) and Azgly residue correctness)
2. Complete HPLC impurity distribution data, not only nominal purity values
3. Independent batch COA with full production and testing traceability records
4. Supplier's mature experience in special modified long-chain decapeptide synthesis
5. Complete export compliance document package for cross-border laboratory procurement
Complete QC Inspection Workflow
Raw Material Incoming QC → In-process Coupling Rate Real-Time Monitoring → RP-HPLC Purity & Impurity Profiling → LC-MS Identity Sequence Verification → Physicochemical Index Test (Water/Solubility/pH) → Heavy Metal & Microbial Limit Screening → Endotoxin Quantification Test → Final Batch Release & COA Issuance
Core Production Process Highlights
Modified amino acid precise coupling technology reduces racemization impurity generation rate below 0.3% Multi-gradient repeated HPLC purification ensures ultra-low related peptide impurity profile Independent constant-temperature clean workshop avoids cross-contamination during synthesis and lyophilization
What Standard Checklist For Buying Reliable Hexarelin API?
|
Order Type |
Quantity Range |
R&D Application Scenario |
|---|---|---|
|
Lab Sample Order |
10mg – 100mg |
Preliminary cell experiment & model validation |
|
R&D Batch Order |
1g – 10g |
Small-scale preclinical mechanism & efficacy trials |
|
Bulk Industrial Order |
Custom KG Grade |
Long-term laboratory stable supply & formulation research |
What Is the Price of Goserelin Acetate API?
Before bulk procurement, biotech R&D procurement teams must verify 6 core standards to avoid low-quality peptide raw materials interfering with experimental repeatability:
- Full sequence identity verification capability: Require original LC-MS mass spectrum report for each delivery batch, not only nominal purity parameters
- Stable batch-to-batch quality consistency: Confirm supplier owns dedicated SPPS peptide production line and standardized SOP management system
- Complete batch traceability system: Exclusive unique batch number covering all synthesis, purification and testing records for audit
- Full set export compliance document support: COA, HPLC chromatogram, MSDS, ISO/GMP certification to guarantee smooth cross-border customs clearance
- Stable large-scale bulk supply capacity: Continuous raw material stock reserve to avoid delayed delivery of kilogram-level bulk orders
- Professional peptide technical after-sales service: One-to-one guidance on dissolution ratio, storage precautions and experimental operation troubleshooting
HDM BIO integrates modified peptide synthesis, multi-stage chromatographic purification and full-spectrum analytical testing to deliver stable Hexarelin API supply for global scientific research buyers.
What Are MOQ & Packaging Options For Hexarelin Bulk Orders?
| Order Tier | Quantity Range | Typical Laboratory Application | Standard Production Lead Time |
|---|---|---|---|
| Lab Trial Sample | 100mg – 1g | Preliminary cell model & small-scale mechanism testing | 3–7 working days |
| Medium R&D Batch | 5g – 50g | Medium-volume preclinical efficacy comparative experiments | 7–15 working days |
| Industrial Large Bulk | Custom Kilogram Volume | Long-term biotech lab fixed procurement & reagent formulation | 10–20 working days |
Why Choose HDM BIO As Your Hexarelin API Supplier?
- Over 10 years of specialized modified peptide R&D and SPPS synthesis manufacturing experience in China, mature production technology for methylated hexapeptides
- ISO 9001 & HACCP certified GMP-aligned class 100,000 dust-free clean production system
- Independent fully equipped analytical QC laboratory with HPLC, LC-MS, moisture analyzer and microbial testing equipment
- Strict full-process batch traceability management for every lot of Hexarelin API raw material
- Stable continuous bulk supply capacity supporting long-term fixed procurement for global biotech and pharmaceutical R&D clients
- Multilingual international sales team with rich cross-border export logistics experience to 70+ countries worldwide
- Full-cycle professional technical support covering pre-sales parameter consultation, dissolution guidance and post-delivery experimental problem solving
FAQs About Hexarelin
Q1: What is the official CAS number of Hexarelin (Examorelin)?
A: The unique CAS registry number of Hexarelin peptide powder is 140703-51-1.
Q2: What purity grade of Hexarelin API can HDM BIO supply?
A: Our standard research-grade Hexarelin has HPLC purity ≥98.0%; customized ultra-high purity ≥99.5% specifications can be produced according to special laboratory research demands.
Q3: What complete testing documents will be provided with each shipment batch?
A: Every order includes official batch Certificate of Analysis (COA), original RP-HPLC purity chromatogram, MSDS safety data sheet; LC-MS mass spectrum identity report can be provided upon customer request.
Q4: Is Hexarelin powder allowed for human clinical injection or athletic use?
A: Absolutely not. This product is strictly research-grade peptide raw material, only permitted for in-vitro laboratory and preclinical animal model research, prohibited for any human body administration, clinical treatment or sports performance enhancement use.
Q5: What is the correct storage method for Hexarelin lyophilized powder?
A: Seal packaging tightly, store in dry, light-proof environment at constant -20℃; avoid repeated freeze-thaw cycles after opening the package to maintain long-term peptide biological activity. Short-term temporary storage (within 30 days) can be kept at 2–8℃ refrigeration.
Q6: Can I apply for free trial samples before formal bulk cooperation?
A: Yes, we support sample orders with complete batch testing documents for preliminary laboratory experimental evaluation.
Q7: What is the shelf life of Hexarelin powder under standard storage conditions?
A: Under recommended sealed, dry, -20℃ light-proof storage environment, the valid shelf life is 24 months. We recommend full experimental use within the marked validity period to guarantee accurate and repeatable research data.
Q8: Does HDM BIO support custom peptide synthesis service?
A: Yes, we provide full customized peptide services including different purity grades, amino acid sequence modification, special salt conversion and customized packaging specifications. Contact our technical team to submit detailed customization requirements.
What Compliance & Technical Review Standards Apply to Hexarelin API?
Scientific Content Review
Reviewed by: HDM BIO Peptide Chemistry & Endocrinology Technical Expert Team Professional Expertise:
Modified hexapeptide Fmoc SPPS synthesis process optimization
Multi-stage HPLC gradient purification for methylated peptide impurities removal
LC-MS peptide sequence identity verification & quantitative purity analysis
GMP-standard peptide raw material full-process quality management system
Review Scope: Hexarelin synthesis process validation, physicochemical specification compliance, HPLC/LC-MS testing data accuracy, laboratory research application rationality Last Updated: August 2026 Manufacturer: HDM BIO Production Base Location: China Quality System Certifications: GMP-aligned production standard, ISO 9001 & HACCP, CNAS analytical lab qualification Intended Exclusive Use: Pharmaceutical preclinical & university laboratory research raw material only; human/animal clinical therapeutic use is strictly forbidden.
Important Global Regulatory Notice
Hexarelin API is defined as research-grade synthetic peptide raw material. All sales and cross-border deliveries are limited to qualified scientific laboratories, biotech enterprises and pharmaceutical R&D institutions. All purchasers must fully comply with local chemical, peptide and pharmaceutical import & export regulatory laws of destination countries. All page content serves only B2B raw material procurement technical reference, and shall not be interpreted as clinical drug guidance or therapeutic application suggestion.
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How to Request Hexarelin COA, Lab Samples & Bulk Wholesale Quotation?
We provide full one-stop procurement support for global pharmaceutical firms, biotech labs and university research institutes sourcing Hexarelin Powder (CAS 140703-51-1):
- Batch-specific COA
- MSDS Safety Data Sheet
- GMP & ISO Certification Documents
- Custom Bulk Wholesale Pricing
- Free Samples Available
- Dedicated Technical Formulation Support
Request COA Get Bulk Pricing Request Sample
WhatsApp: +86 19991242181
Email: sales@hdmbio.com
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