Native GLP-1 (7-36) amide Peptide API Manufacturer China | Bioactive Peptide Supplier CAS 107444-51-9

Core Selling Points

✓ ≥98% HPLC Purity

✓ LC-MS Full Sequence Verification

✓ Batch-Specific COA Available

✓ GMP-Aligned Production System

✓ Global Export Regulatory Support

✓ Custom Peptide Synthesis Service

What Is Native GLP-1 (7-36) amide API Powder & Its Research Applications?

GLP-1 (7-36) amide peptide powder is the biologically active endogenous fragment of glucagon-like peptide-1, classified as a native bioactive GLP-1 receptor peptide, not a synthetic analogue. It targets GLP-1 receptors to regulate glucose metabolism, insulin secretion and gastrointestinal motility. This peptide raw material is widely adopted in diabetes mechanism research, metabolic pharmacology studies, and preclinical peptide drug exploratory research.

Produced via optimized Fmoc solid-phase peptide synthesis technology and multi-stage gradient HPLC purification, our GLP-1 (7-36) amide maintains intact native peptide sequence, stable biological activity and consistent batch quality. This product is for laboratory and R&D use only, not for direct clinical administration.

What Are the Official Quality Standards for GLP-1 (7-36) amide API?

Every production batch of GLP-1 (7-36) amide undergoes dual QC testing (HPLC + LC-MS) in HDM BIO's in-house analytical laboratory. An independent batch COA will be issued for all bulk orders.

Item	Specification	Result
Appearance	White to off-white powder	Consistent
Purity (HPLC)	≥98%	99.95%
MS Identity	Consistent with reference standard	Confirmed
Conclusion	Cosmetic raw material requirement	Passed

What Should You Check When Buying GLP-1 (7-36) amide API?

When sourcing GLP-1 (7-36) amide API powder for pharmaceutical research, procurement teams and laboratories should verify the following core standards to guarantee quality and stable supply:

1. Purity verification: Confirm ≥98% HPLC purity together with official chromatogram and impurity profile data

2. Sequence confirmation: Require LC-MS full-length native peptide sequence verification to avoid incomplete peptide impurities

3. Quality documentation: Ensure each production batch is equipped with exclusive batch COA and complete traceability records

4. Manufacturing capability: Confirm mature SPPS production capacity and standardized quality control systems

5. Export support: Secure complete regulatory documents and technical support for international customs clearance

What Makes GLP-1 (7-36) amide API a High-Precision Synthetic Peptide?

GLP-1 (7-36) amide peptide powder belongs to long-chain linear native bioactive GLP-1 fragment with strict synthesis technical barriers. Long peptide chain coupling easily generates missing amino acid impurities, which directly affect native biological activity and receptor binding ability.

Core manufacturing challenges include continuous accurate amino acid coupling control, efficient removal of truncated peptide impurities, and complete preservation of native biological activity during purification and lyophilization. HDM BIO adopts optimized SPPS coupling process and multi-stage high-precision HPLC purification. Each batch supports full-process LC-MS structural verification to guarantee complete native peptide sequence and stable batch consistency.

How Does GLP-1 (7-36) amide Work in Pharmacological Research?

GLP-1 (7-36) amide API is an active native endogenous GLP-1 fragment, activating GLP-1 receptors to modulate glucose homeostasis, applied for physiological metabolism and preclinical peptide drug research.

As a native ligand of GLP-1 receptor, GLP-1 (7-36) amide stimulates glucose-dependent insulin secretion, inhibits glucagon release and delays gastric emptying. It serves as a critical control raw material for studying metabolic disorders, screening GLP-1 targeted lead compounds and evaluating long-acting GLP-1 analogues.

What Is the Difference Between Native GLP-1 (7-36) amide and GLP-1 Analogues?

Native GLP-1 fragments and synthetic GLP-1 analogues differ greatly in structural source, half-life and research usage. This comparison clarifies core characteristics for targeted metabolic research:

Peptide Type	Core Characteristics & Research Value
Native GLP-1 (7-36) amide	Endogenous bioactive fragment; short physiological half-life; used for native GLP-1 receptor mechanism and glucose metabolism baseline research
Semaglutide	Fatty acid modified long-acting GLP-1 analogue; artificially optimized structure; applied for long-term hypoglycemic drug development and efficacy evaluation
Tirzepatide	Dual GIP/GLP-1 receptor synthetic peptide; multi-target activation; used for compound metabolic drug preclinical research

How Does GLP-1 (7-36) amide Compare to Other GLP-1 Family Peptides?

Different GLP-1 peptides differ in structural attributes, metabolic stability and receptor activation characteristics for diverse research directions.

Explore our complete GLP-1 peptide API portfolio: GLP-1 (7-36) amide, Exenatide, Liraglutide, Semaglutide, Tirzepatide for comprehensive metabolic disease peptide research solutions.

Ingredient	Mechanism Type	Core R&D Application	CAS Number
GLP-1 (7-36) amide	Native active GLP-1 fragment, short half-life	Endogenous GLP-1 physiological mechanism baseline research	107444-51-9
Exenatide	Exogenous GLP-1 receptor agonist peptide	GLP-1 receptor activation comparative pharmacological study	141732-76-5
Liraglutide	Long-acting fatty acid modified GLP-1 analogue	Preclinical long-acting hypoglycemic drug research	204656-20-2
Semaglutide	Fatty acid modified long-acting GLP-1 analogue	Chronic metabolic disease drug development research	910463-68-2
Tirzepatide	Dual GIP/GLP-1 receptor agonist	Dual-target metabolic drug preclinical research	2023788-19-2

How Is GLP-1 (7-36) amide API Manufactured & Quality Controlled?

GLP-1 (7-36) amide is synthesized via mature Fmoc solid-phase peptide synthesis, multi-stage impurity purification and standardized lyophilization processes to ensure complete native peptide sequence and biological activity. For detailed analysis, view our guide: How Is Long-Chain Bioactive Peptide Manufactured? Full SPPS Process Explained

Production Workflow

Raw Material Inspection → Fmoc SPPS Sequential Coupling → Resin Cleavage → Multi-stage HPLC Purification → Vacuum Lyophilization → QC Testing → Batch COA Issuance → Sealed Light-Proof Pharmaceutical Packaging

QC Inspection Workflow

Incoming Raw Material QC → In-process Peptide Coupling Monitoring → HPLC Purity Testing → Mass Spectrometry Identity & Sequence Verification → Moisture & Heavy Metal Testing → Residual Solvent Detection → Final Batch Release Approval

Core Process Highlights

- Optimized long-chain coupling technology reduces truncated peptide by-products and protects native peptide activity - Multi-stage high-precision HPLC purification thoroughly removes structural impurities to ensure batch consistency

How to Choose a Reliable GLP-1 (7-36) amide API Manufacturer?

Long-chain native GLP-1 fragment peptide synthesis has high technical thresholds. Evaluate suppliers based on these core dimensions:

1. Quality system: GMP-aligned production environment with ISO & HACCP certification

2. Testing capability: Dual HPLC + LC-MS full sequence verification for every production batch

3. Technical strength: Independent SPPS long native peptide synthesis workshop

4. Traceability: Complete batch production records and exclusive COA documentation

5. Export support: Full customs clearance documents and global logistics experience

HDM BIO provides stable GLP-1 (7-36) amide API supply with integrated peptide synthesis, purification and quality testing capabilities in China.

What Are the MOQ Options for GLP-1 (7-36) amide API Bulk Orders?

Order Type	Quantity Range	Typical Use Case	Lead Time
Research Sample	10mg – 100mg	Laboratory evaluation & preliminary testing	3 – 7 working days
R&D Batch	1g – 10g	Small-scale formulation & efficacy study	7 – 15 working days
Bulk Production	Custom quantity	Industrial scale API manufacturing	10 – 20 working days

What Factors Affect GLP-1 (7-36) amide API Bulk Pricing?

GLP-1 (7-36) amide API bulk pricing varies based on multiple procurement and customization factors:

- Purity grade: ≥99% high-purity grade carries higher cost than standard ≥98% research grade

- Order volume: Larger bulk orders qualify for tiered pricing discounts

- Customization: Custom peptide modification or salt form adjustment increases production cost

- Additional testing: Third-party testing or full sequence mapping services affect final quotation

- Logistics: Custom pharmaceutical packaging or cold-chain shipping adds overall cost

HDM BIO provides flexible tiered pricing for milligram-level samples, medium-batch R&D supply and large-scale bulk wholesale. Contact our sales team for the latest real-time quotation and production lead time.

Why Choose HDM BIO As Your GLP-1 (7-36) amide API Supplier?

- 10+ years of professional native GLP-1 series peptide API manufacturing experience in China

- ISO & HACCP certified quality system with GMP-aligned production workshops

- Strict LC-MS native sequence verification and full production traceability per batch

- Flexible supply from lab trial samples to large-scale industrial bulk orders

What Are Common Questions About GLP-1 (7-36) amide API?

Q: Where can I buy GLP-1 (7-36) amide API powder from China?

A: HDM BIO is a China-based GMP-aligned GLP-1 (7-36) amide API manufacturer, supplying high-purity native GLP-1 peptide powder to global pharmaceutical and biotech R&D institutions. We support small research samples and large bulk orders with complete export documents.

Q: What documents should a GLP-1 (7-36) amide API supplier provide?

A: Qualified suppliers provide batch-specific COA, HPLC purity chromatogram, LC-MS sequence verification report, MSDS, ISO/HACCP certification and production traceability records.

Q: How is GLP-1 (7-36) amide API purity verified?

A: Purity is tested via HPLC for peptide content and impurity levels, while LC-MS confirms molecular weight and full native peptide sequence integrity to meet pharmaceutical research standards.

Q: What is the CAS number of GLP-1 (7-36) amide?

A: The CAS registry number of GLP-1 (7-36) amide is 107444-51-9.

Q: What purity grades of GLP-1 (7-36) amide API do you offer?

A: We provide standard ≥98% HPLC pharmaceutical grade, and customized ≥99% high-purity specifications for advanced research needs.

Q: Is GLP-1 (7-36) amide a native peptide or synthetic analogue?

A: GLP-1 (7-36) amide peptide powder is a native endogenous bioactive GLP-1 fragment, not a synthetic GLP-1 analogue, widely used for physiological metabolism mechanism research.

Q: How to store GLP-1 (7-36) amide lyophilized powder?

A: Store sealed at -20°C, protected from light and moisture. Avoid repeated freeze-thaw cycles to maintain peptide biological activity.

Q: Can I get custom peptide synthesis service?

A: Yes. We support custom purity adjustment, peptide modification, personalized packaging and targeted peptide synthesis services.

Q: Can I get GLP-1 (7-36) amide API samples before bulk orders?

A: Yes. We provide milligram to gram-level trial samples with complete test documents for R&D evaluation before formal bulk cooperation.

Q: What is the MOQ for GLP-1 (7-36) amide API bulk orders?

A: We have flexible MOQ, supporting small-batch experimental procurement and large-scale industrial bulk orders to meet different project needs.

Who Reviews GLP-1 (7-36) amide API Technical Content & Quality Standards?

Written by: HDM BIO Pharmaceutical Peptide Technical Content Team Specialized in peptide API industry analysis, metabolic pharmacology R&D applications and GMP manufacturing standards.

Reviewed by:

- HDM BIO Peptide Chemistry Team

- HDM BIO Quality Assurance Department

- HDM BIO Analytical Testing Laboratory

Review Scope: Native GLP-1 long-chain peptide synthesis pathway, purification compliance, HPLC & MS analytical method validity, GMP-aligned production control requirements.

Last Updated: August 2026