Beta Estradiol (17 β Estradiol) CAS 50-28-2 Raw Material Supplier | GMP Pharmaceutical Grade
Core Selling Points:
● Endogenous bioactive estrogen, ≥99% purity (HPLC), pharmaceutical-grade 17 β estradiol raw material
● Suitable for pharmaceutical formulations and scientific research applications
● Stable, reproducible, and compatible with tablets, capsules, creams, and gels
● Complete COA, HPLC, MSDS, and TDS documentation for regulatory and audit compliance
● Flexible global supply, competitive bulk price, and fast international delivery with technical support
Product Overview
β-Estradiol (CAS 50-28-2), also known as 17 β estradiol, is a naturally occurring endogenous estrogen and the most biologically active steroidal estrogen in the human body. This high-purity human-use raw material is supplied as a white crystalline powder with stable physicochemical properties, high purity (≥99% HPLC), and strictly controlled impurities. It is exclusively intended for pharmaceutical formulation development and endocrine research applications.
Manufactured using refined synthesis and multi-stage purification processes, this 17 β estradiol API ensures consistent batch-to-batch quality and moderate solubility. It is compatible with tablets, capsules, creams, gels, and other formulation types. Fully compliant with international pharmacopoeia standards (USP, EP), and produced under GMP conditions, this material is widely adopted by global pharmaceutical companies, academic laboratories, and research institutions as a core estrogen raw material.
COA
| Item | Specification | Result | |
| Characteristics | White or creamy white powder. | Conform | |
| Identification | A: IR B: UV |
Conform | |
| Melting range | 173~179℃ | 176.9~177.1℃ | |
| Specific rotation | +76° ~+83° | +82.2° | |
| Relate substance Any individual impurity Total impurities |
≤0.5% ≤1.0% |
0.07% 0.09% |
|
| Water | ≤3.5% | 3.38% | |
| Assay | 97.0~103.0% | 99.61% | |
| Micron | 100%≤20μm | Conform | |
| Conclusion | The product complies with the requirements of USP Standard. | ||
Mechanism of Action
β-Estradiol (17 β estradiol) specifically binds to estrogen receptors, regulating gene expression and cell signaling pathways. It participates in the physiological metabolism of the reproductive system, bones, skin, cardiovascular system, and endocrine tissues.
As an active endogenous estrogen, it supplements and balances estrogen levels. It regulates pituitary gonadotropin secretion rhythms, maintains menstrual cycle stability, supports bone metabolism, and promotes normal differentiation and repair of soft tissues.
In research, 17 β estradiol is widely used to induce cell differentiation, construct hormone intervention models, and study endocrine and pharmacological mechanisms.
Product Applications
● Pharmaceutical Formulations: Used as a raw material for oral tablets, creams, gels, and transdermal patches; ideal for endocrine-related drug development
● Life Science Research: Supports cell culture, hormone pathway studies, endocrine pathology modeling, and pharmacological experiments
● Biochemical Assay Standards: Used for hormone detection calibration and analytical reference standards
Detailed Benefits
● Endocrine Balance Regulation: Participates in hypothalamic-pituitary-ovarian axis regulation
● Female Physiological Support: Maintains endometrial health and reproductive cycle stability
● Menopause Support: Helps reduce discomfort caused by estrogen fluctuation
● Bone Metabolism Support: Supports calcium regulation and bone density maintenance
● Skin & Mucosa Care: Promotes collagen synthesis and hydration balance
Core Advantages
● High Purity & Low Impurities: HPLC ≥99%, strictly controlled residual solvents and heavy metals
● Stable Endogenous Activity: Maintains configuration of 17 β estradiol, suitable for multiple dosage forms
● Flexible Global Supply: Supports bulk orders, sample requests, and worldwide shipping
Quality Assurance
● Multi-step strict quality control: Each batch undergoes HPLC testing and physicochemical verification
● Pharmacopoeial compliance: Meets USP and EP standards for pharmaceutical-grade raw materials
● Complete documentation: Full regulatory support documents provided
● Full traceability: From raw material sourcing to final shipment
FAQ
Q1: What is 17β-Estradiol?
A: It is an estrogen API, widely used in human pharmaceuticals and veterinary medicine.
Q2: What research applications is 17 β estradiol suitable for?
A: Endocrine pharmacology studies, hormone pathway research, cell differentiation assays, and steroid drug development.
Q3: What dosage forms are supported?
A: Tablets, capsules, creams, gels, and transdermal patches.
Q4: Do you test residual solvents and heavy metals?
A: Yes. Residual solvents and heavy metals are strictly controlled within pharmacopoeia limits.
factory
Certificates
Shipping & Packing
Order Now | Stable Global Supply
Order high-purity 17 β estradiol API for wholesale procurement at competitive prices.
We support bulk purchasing, sample requests, and fast international shipping.
Contact us for COA, GMP documentation, and customized supply solutions.
Whatsapp & Mobile: +8619991242181
Email: sales@hdmbio.com
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