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LL-37 Peptide Powder

LL-37 Peptide Powder

Appearance: White to off white powder
Specification: 98% min
CAS Number: 597562-32-8
Molecular Formula: C205H341N61O52
Molecular Weight: 4492.27854
EINECS: 200-001-8
Shelf Life: 2 Years Proper Storage
Stock: Fresh Stock
Certificate: COA,GMP,ISO,HACCP
Service: OEM&ODM Service

Product Introduction

LL-37 Peptide Powder | High-Purity Antimicrobial & Immune-Regulatory Research Peptide | GMP-Compliant Bulk Supply

Core Highlights
Broad-spectrum antimicrobial & antiviral|Biofilm disruption|Bidirectional immune modulation|Wound healing promotion|Neuroprotection & antioxidant|Suitable for research & formulation development|High-purity bulk procurement support

Product Overview

Human Cathelicidin Antimicrobial Peptide LL-37 (LL-37 Peptide Powder) is the only human-derived Cathelicidin antimicrobial peptide, consisting of 37 amino acids. It is an active fragment derived from the precursor protein hCAP-18, encoded by the CAMP gene and activated by proteinase 3. Widely present in neutrophils, epithelial cells, and mucosal tissues, LL-37 Peptide Powder is an essential component of the human innate immune system.

Prepared using solid-phase peptide synthesis, the molecular sequence is identical to endogenous LL-37, forming an amphipathic α-helical conformation. The powder is high-purity, low in impurities, and biologically stable, free from animal-derived contaminants. It is ideal for buyers seeking high-purity, cost-effective bulk procurement. Its dual features-broad-spectrum antimicrobial activity and immune modulation-are backed by extensive scientific data, making it suitable for antimicrobial, immune regulation, and wound repair applications, as well as overseas research experiments, formulation development, and functional product R&D. This effectively addresses limitations of traditional antibiotics, including resistance and narrow antimicrobial spectrum.

COA

Item Specification Result
Appearance White to off White powder Consistent
Purity(HPLC) ≥98%
 
98.03%
MS Consistent Consistent
Conclusion The product complies with the requirements

Mechanism of Action

LL-37 Peptide Powder is an endogenous antimicrobial peptide. Its amphipathic α-helical structure allows selective binding to negatively charged pathogen membranes while sparing neutral human cells, enhancing safety over traditional antibiotics.

● Antimicrobial Mechanism – Electrostatic binding, oligomerization, pore formation, membrane disruption, leakage of intracellular contents.         Inhibits protein synthesis and genome integrity. Low risk of resistance, suitable for long-term research.

● Immune Modulation – Binds FPRL1 on immune cells, recruits immune cells, promotes interferon and interleukin secretion, neutralizes LPS, suppresses excessive pro-inflammatory factors, maintaining homeostasis.

● Biofilm & Wound Repair – Disrupts biofilms, activates cell proliferation and migration, promotes angiogenesis. Neuroprotective and antioxidant effects enhance multifunctional applications, ideal for bulk Chinese procurement of LL-37 Peptide Powder.

Product  Applications

1. Pharmaceutical Research Applications
Used in antimicrobial, antiviral, immune-regulation, and wound-repair formulation research for injectable, oral, and topical studies.

2. Scientific Research Material
Suitable for immunology, microbiology, virology, wound healing, and biofilm-related research applications.

3. Functional Formulation Development
Applicable to skincare, oral care, and nutritional formulation research focused on antimicrobial and immune-support functions.

4. Custom Peptide Development
Supports derivative design, structural optimization, and long-acting peptide development with flexible bulk supply and technical support.

Detailed Efficacy

1. Broad-Spectrum Antimicrobial Activity
Supports antibacterial and antifungal research by disrupting microbial membranes and inhibiting pathogen growth.

2. Antiviral Research Potential
Applicable to studies involving viral attachment inhibition and suppression of viral replication pathways.

3. Biofilm Disruption Support
Helps penetrate and disrupt bacterial biofilms for chronic infection and antimicrobial research applications.

4. Immune-Regulatory Activity
Supports immune cell signaling and balanced inflammatory response research.

5. Wound-Healing Support
Promotes cell migration, tissue repair, and angiogenesis in wound-repair formulation studies.

6. Neuroprotective & Antioxidant Research
Supports studies on oxidative stress reduction, neuronal protection, and cytokine regulation.

Product  Advantages 

● Precise Synthetic Structure
Produced by SPPS with the same amino acid sequence as endogenous LL-37 for high consistency and reliable bioactivity.

●  Immune-Regulatory Activity
Supports pathogen defense and inflammatory balance in immune and infection research.

●  Multifunctional Research Value
Combines antimicrobial, wound-healing, neuroprotective, and antioxidant research potential in one peptide platform.

●  Flexible Supply Options
Available in multiple purity grades and packaging sizes for laboratory research, pilot studies, and bulk procurement.

Core advantages

● Standardized GMP Manufacturing
Produced using advanced technology in GMP-compliant clean facilities with strict impurity and endotoxin control.

● Comprehensive Quality Traceability
Each batch is supported by HPLC, amino acid, microbial, and endotoxin testing with complete QC documentation.

● Global Compliance Support

With COA, MSDS and supporting export documents for international procurement.

● Stable Bulk Supply Capacity
Scalable production, flexible packaging, and fast response for both sample and large-volume orders.

● Professional Technical Assistance
Technical support available for formulation development, application guidance, and research compliance needs.

Quality Assurance 

● Raw Material Control – High-purity amino acids and rigorously screened reagents ensure sequence accuracy and low impurities, providing a solid foundation for premium LL-37 Peptide Powder.

● Production Control – High-class cleanroom, sterile operation, full GMP compliance, precise control of temperature, humidity, and environment, meeting international export standards.

● Testing Control – HPLC and MS verification, moisture, acetate, microbial, and endotoxin testing. Full QC report for every batch ensures traceable quality.

● Compliance Control – Adheres to international peptide raw material standards, providing full export compliance documentation.

● After-Sales Support – Batch tracking system, unique batch numbers, fast resolution of any quality issues. Bulk procurement includes technical solutions, protecting buyer interests.

FAQ

Q1: How does LL-37 Peptide Powder compare to traditional antibiotics?
A: Traditional antibiotics often target single sites, leading to resistance and potential harm to normal cells. LL-37 Peptide Powder employs multi-mechanism pathogen disruption, low resistance, bidirectional immune modulation, antiviral activity, biofilm disruption, and wound healing. Safer and broader in application. Bulk Chinese procurement ensures competitive pricing.

Q2: What pathogens does LL-37 Peptide Powder cover?
A: Gram-positive bacteria (S. aureus), Gram-negative bacteria (P. aeruginosa, E. coli), fungi (C. albicans), and enveloped viruses (influenza A, SARS-CoV-2).

Q3: Suitable product development applications?
A: Antimicrobial and antiviral formulations (injectables, oral, topical), high-end dietary supplements, skincare, immune-regulating products. 

factory

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Certificates

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Shipping & Packing

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Order Now

High-purity LL-37 Peptide Powder from a trusted Chinese supplier. Stable quality, efficient supply, strong compliance. Ideal for research, formulation, and functional product development. 

Contact:
Whatsapp & Mobile: +86 19991242181

Email: sales@hdmbio.com

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