Vapreotide Acetate Powder | High‑Purity Synthetic Somatostatin Analog Research Peptide

Core Selling Points

✅ Request Custom Bulk Quotation

✅ Download Batch‑Specific COA

✅ Technical data support

✅ Global shipping & customs‑ready documents

What Is Vapreotide Acetate Powder (CAS 103222‑11‑3)?

Vapreotide Acetate powder is a synthetic cyclic somatostatin‑analog octapeptide containing an intramolecular disulfide bridge. It is widely adopted as research tool compound exploring somatostatin receptor‑associated pathways. Manufactured by optimized Fmoc solid‑phase peptide synthesis with controlled cyclization, our Vapreotide Acetate powder strictly monitors cysteine oxidation, disulfide isomers and deletion‑sequence impurities. Directional oxidation‑cyclization process delivers reliable structural integrity and analytical consistency together with good batch‑to‑batch reproducibility. HDM BIO serves universities, biotech labs and pharma R&D teams worldwide, supporting mg‑g lab samples up to kg‑scale bulk procurement.

Important note: This material is for pre‑clinical laboratory research only; not for human clinical use, diagnosis or medication.

What Are The Quality Specifications of Vapreotide Acetate Powder?

Every production batch of Vapreotide Acetate powder undergoes full QC inside our in‑house peptide analytical lab. Each shipment comes with batch‑specific COA and supporting test reports to satisfy lab audit and cross‑border customs requirements.

Item	Specification	Result
Appearance	White to off-white powder	Consistent
Purity (HPLC)	≥98%	99.93%
MS Identity	Consistent with reference standard	Confirmed
Conclusion	Cosmetic raw material requirement	Passed

Vapreotide Acetate vs Somatostatin vs Octreotide: What Are The Differences?

For researchers selecting somatostatin‑class peptide raw materials, the comparison below clarifies structural and research‑use distinctions:

Peptide	Core Research Focus	Structural Characteristics	Main Research Applications	CAS Number
Vapreotide Acetate	Somatostatin receptor subtype interaction studies	Cyclic octapeptide synthetic somatostatin analog, disulfide‑bond constrained	Endocrine signaling, cell proliferation, receptor pharmacology in pre‑clinical models	103222‑11‑3
Somatostatin Acetate	Endogenous native hormone reference	Native cyclic tetradecapeptide	Neuroendocrine feedback, hormone regulation mechanism research	38916‑34‑6
Octreotide Acetate	Widely‑studied short‑half‑life analog	Cyclic octapeptide, sequence differs from vapreotide	Endocrine tumor model, inhibitory pathway pre‑clinica

How to Buy High‑Quality Vapreotide Acetate Powder From China?

When sourcing Vapreotide Acetate powder for pre‑clinical projects, international R&D teams should evaluate these five key criteria to reduce experimental risk:

HPLC purity validation: Confirm ≥98% HPLC with batch‑specific COA; pay special attention to disulfide‑bond isomer and cysteine‑oxidation impurities that can interfere assay outcomes.
Multi‑mode structural confirmation: Qualified lots require HPLC, LC‑MS and amino‑acid composition analysis to validate full‑length octapeptide and correct disulfide‑bond arrangement.
Complete documentation set: Supplier must provide COA, HPLC chromatogram, LC‑MS report and MSDS for laboratory audit and import customs clearance.
Cyclic peptide manufacturing competence: Choose a peptide producer experienced in Fmoc‑SPPS cyclization and oxidative‑impurity control for disulfide‑containing peptides.
Flexible supply capacity: Support small lab‑trial quantities as well as large‑volume bulk orders for long‑term research programs.

How Much Does Vapreotide Acetate Powder Cost? Price & Bulk Order Guide 2026

For Vapreotide Acetate powder price, bulk quotation and delivery terms, review the procurement guidance:

Flexible MOQ: Milligram‑gram lab samples for preliminary experiments; kilogram‑scale bulk for sustained R&D projects.
Sample service: Paid test samples with full QC documents available for pre‑bulk evaluation.
Volume‑tiered pricing: Larger bulk orders receive improved per‑unit cost.
Production lead‑time: Cyclic disulfide‑bond peptide requires cyclization and anti‑oxidation controls; exact lead‑time will be confirmed by sales based on order size.
Global shipping: Light‑proof sealed low‑oxygen packaging to resist moisture and oxidation; full customs‑clearance documents provided.

What Verification Steps Should Global Buyers Take Before Procurement?

Before placing orders for Vapreotide Acetate powder, international procurement teams are recommended to complete these checks:

Audit supplier facilities: Confirm independent peptide synthesis workshop and QC laboratory with proven track record for cyclic disulfide‑bond peptide production.

Pre‑review test documentation: Request batch chromatograms focusing on oxidation and isomer‑related impurity profiles.

Confirm product parameters: Match purity, endotoxin index and storage conditions against your experimental protocol. Vapreotide Acetate powder is hygroscopic and oxidation‑prone.

Confirm production & delivery timeline: Align sample / bulk lead‑time with your research project milestones.

Verify export document capability: Ensure commercial invoice, packing list and supporting material certificates can be issued for local import requirements.

Why Choose HDM BIO for Vapreotide Acetate Powder Manufacturing?

HDM BIO has rich know‑how for complex cyclic disulfide‑bond peptide synthesis under GMP‑aligned quality system:

Mature directional cyclization technology lowering disulfide‑mismatch isomer by‑products.
Full‑process inert‑gas shielding and low‑light operation to suppress cysteine oxidation degradation.
Multi‑stage preparative RP‑HPLC purification for baseline separation of deletion fragments and oxidative impurities.
Every batch passes HPLC, LC‑MS identity check plus amino‑acid composition analysis for consistent analytical quality.
Products exported worldwide for university labs, biotech startups and pharmaceutical R&D institutes.
Offer custom peptide analog synthesis and technical consulting for somatostatin‑family peptide research.

Why Is Vapreotide Acetate Peptide Manufacturing Technically Challenging?

As a cyclic octapeptide carrying intramolecular disulfide linkage, Vapreotide Acetate powder presents notable production obstacles:

Disulfide‑bond isomer risk: Two cysteine residues can form incorrect cross‑links during oxidation, generating structurally invalid isomers hard to separate by standard purification.
Oxidative degradation: Cysteine residues are sensitive to oxygen and ambient light, easily forming oxidized impurities impacting analytical consistency.
Accumulation of truncated impurities: Step‑wise Fmoc coupling may produce deletion‑sequence fragments with similar polarity, raising purification difficulty for reaching ≥98% target purity.

What Is The Research Mechanism of Vapreotide Acetate Powder?

Vapreotide Acetate powder is a synthetic somatostatin analog peptide used in academic laboratory work. In pre‑clinical assay systems, it is studied for biological pathways related to somatostatin‑receptor binding and downstream intracellular signaling cascades. All described observations are limited to in‑vitro and animal model research scenarios, purely for academic investigation.

What Is The Complete Production & QC Workflow of Vapreotide Acetate Powder?

Vasopressin powder is a key neuroendocrine regulatory peptide in vivo. It specifically binds to V1 and V2 receptors on target cells, activates downstream cAMP and calcium ion signaling pathways, andis studied for two major biological pathways: 1. Acting on renal collecting duct cells to promote water reabsorption and maintain body fluid osmotic pressure balance; 2. Acting on vascular smooth muscle to induce vasoconstriction and regulate blood pressure stability. In addition, it participates in central nervous system stress response, emotional regulation and neuroendocrine feedback regulation. All mechanisms are limited to in vitro and pre-clinical animal research scenarios, for academic study only.

What Is The Complete Production & QC Workflow of Vapreotide Acetate Powder?

Manufacturing Workflow

Fmoc‑amino‑acid incoming QC → Step‑wise solid‑phase coupling synthesis → Resin cleavage & global deprotection → Low‑temperature directional disulfide‑bond cyclization under nitrogen atmosphere → Crude peptide pre‑treatment → Multi‑stage preparative HPLC purification → Buffer exchange → Vacuum lyophilization under low‑oxygen dark environment → Finished‑product full‑index QC → Batch COA issuance → Nitrogen‑filled light‑proof sealing packaging

QC Inspection Workflow

Raw‑material incoming inspection → In‑process monitoring for oxidation & isomer impurities → HPLC purity test → LC‑MS molecular‑weight identification → Amino‑acid composition analysis → Quantitation of oxidative and deletion impurities → Moisture & heavy‑metal testing → Residual‑solvent detection → Endotoxin assay → Final batch release approval

What Are The Main Application Scenarios of Vapreotide Acetate Powder?

Somatostatin Receptor Pharmacology Research: Receptor‑subtype selectivity, binding‑affinity assay, downstream signal‑pathway exploration
Cell‑Level Pre‑Clinical Assays: Cell proliferation regulation, secretory‑function model studies
Peptide Formulation R&D: Cyclic peptide stability assessment, sustained‑release delivery‑system prototype development
Comparative Peptide Research: Side‑by‑side study against octreotide / native somatostatin in cyclic‑peptide structure‑activity relationship projects
Biochemical Reagent Reference Material: Research‑grade reference compound for disulfide‑bonded somatostatin‑analog peptide laboratory work

Common Questions About Vapreotide Acetate Powder

Q1: Where can I buy Vapreotide Acetate powder CAS 103222‑11‑3 from China?

A1: HDM BIO is an experienced Chinese cyclic‑peptide manufacturer under GMP‑aligned quality framework. We produce high‑purity research‑grade Vapreotide Acetate powder and provide end‑to‑end global supply service.

Q2: What is the CAS number for Vapreotide Acetate powder?

A2: CAS registry number: 103222‑11‑3.

Q3: What purity grade of Vapreotide Acetate powder do you supply?

A3: Standard research‑grade ≥98% HPLC. Custom higher‑purity specifications are available upon request.

Q4: What documents will I receive with Vapreotide Acetate powder orders?

A4: Batch‑specific COA, HPLC chromatogram, LC‑MS report and MSDS. Additional impurity‑profile data can be provided on request.

Q5: How should Vapreotide Acetate powder be stored?

A5: Store nitrogen‑sealed at −20 °C, protect tightly from light, air and moisture; avoid repeated freeze‑thaw cycles. Aqueous reconstituted solution is oxidation‑sensitive; aliquot and store at −80 °C for single‑use only.

Q6: What factors affect Vapreotide Acetate powder price?

A6: The price depends on purity requirement, testing package scope, total order quantity, packaging specification and shipping / cold‑chain conditions. Bulk volume generally brings better unit cost for long‑term research projects.

Q7: Can I obtain trial samples for laboratory testing?

A7: Paid research samples with full QC documentation are available for pre‑bulk laboratory evaluation.

Scientific Review

Reviewed by:

HDM BIO Peptide Technical Team

Expertise:

Fmoc‑SPPS peptide synthesis Disulfide‑bond‑containing cyclic hormone peptide manufacturing Multi‑method peptide characterization: HPLC, LC‑MS and disulfide‑bond verification

Last Updated: August 2026

Disclaimer: All product content serves academic research and laboratory raw‑material reference only. Not for human clinical use, diagnosis or treatment.