Wholesale Bronchogen Peptide Powder, Factory Price 99% HPLC AEDL Tetrapeptide Bioregulator
Key Features
✅ Sequence-Verified - AEDL (Ala-Glu-Asp-Leu) confirmed by LC-MS, not the mis-labeled ADEL
✅ High HPLC Purity - ≥98% with batch-specific chromatogram and COA
✅ Research-Grade Format - TFA-removed lyophilized powder, soluble in water
✅ Custom Synthesis & Bulk - From mg-scale samples to gram/kilogram lots, related cytogen peptides available
What Is Bronchogen?
Bronchogen Peptide is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Leu (AEDL), developed within the Khavinson short-peptide bioregulator research line. It is a member of the "cytogen" family of ultra-short signalling peptides studied for tissue-specific gene-expression modulation in bronchial-epithelium experimental systems. It is supplied as a white, water-soluble lyophilized powder.
HDM BIO supplies Bronchogen Peptide raw powder from milligram-scale samples to gram and kilogram lots for research laboratories, CROs and peptide R&D programs. Note that the AEDL sequence is often mis-listed as ADEL; the confirmed sequence is Ala-Glu-Asp-Leu, and it differs from Epithalon (AEDG) only in the terminal leucine-for-glycine substitution.
This is a research chemical only. It has no approved drug indication and no completed randomized clinical trials; it is not for human or animal administration.
Bronchogen Quality Specifications and Batch Documentation
Every batch is tested in HDM BIO's QC laboratory. Batch-specific COA is provided with each shipment.
| Test Item | Specification | Result |
|---|---|---|
| Appearance | White lyophilized powder | White lyophilized powder |
| Identity (LC-MS) | Conforms to AEDL; m/z 446.45 | Conform |
| Purity (HPLC) | ≥98.0% | 99.2% |
| Net Peptide Content | ≥95.0% | 96.8% |
| Water Content (KF) | ≤8.0% | 4.20% |
| Trifluoroacetic Acid (TFA) | ≤0.5% (TFA removed) | <0.2% |
| Acetate Content (optional) | On request (acetate salt) | Free peptide |
| Bacterial Endotoxin | ≤10 EU/mg (on request) | <5 EU/mg |
| Bioburden | ≤100 CFU/g | Complies |
| Conclusion | The product complies with the requirements |
What Is Bronchogen Used For?
- Bronchial-epithelium research: In-vitro studies of short-peptide effects on respiratory epithelial systems
- Gene-expression research: Experimental work on epigenetic/transcriptional modulation by Khavinson cytogen peptides
- Peptide mechanism studies: Cell-penetration and short-peptide signalling research
- Comparative peptide studies: Side-by-side work with related AED-family tetrapeptides (e.g. Epithalon AEDG)
- Analytical reference: Reference material for LC-MS and analytical method development
All use is restricted to laboratory research. No diagnostic, therapeutic or preventive claims are made, and the material must not be used in humans or animals.
Bronchogen (AEDL) vs Related AED-Family Tetrapeptides
| Peptide | Sequence | Formula / MW | Research Focus |
|---|---|---|---|
| Bronchogen | Ala-Glu-Asp-Leu (AEDL) | C₁₈H₃₀N₄O₉ / 446.45 | Bronchial-epithelium systems |
| Epithalon (Epitalon) | Ala-Glu-Asp-Gly (AEDG) | C₁₄H₂₂N₄O₉ / 390.35 | Pineal/epigenetic research |
| ADEL (mis-listing) | Ala-Asp-Glu-Leu (ADEL) | Same formula, different order | Not Bronchogen - confirm AEDL before ordering |
Note: AEDL and ADEL share the same molecular formula and mass, so the order of Glu/Asp must be verified by sequence analysis. Bronchogen is AEDL. Related HDM BIO research-peptide pages available.
What Supply Options Are Available?
| Supply Type | Availability |
|---|---|
| Analytical / R&D sample (mg scale) | Yes |
| Small batch (1 g – 10 g) | Yes |
| Medium-batch production (10 g – 100 g) | On request |
| Bulk supply (100 g +) | On request |
| Custom sequence / related cytogen peptide | On request |
Prices are negotiable based on order quantity.
What Should Buyers Verify Before Purchasing Bronchogen?
| Buyer Check | Documentation / Method | Purpose |
|---|---|---|
| Sequence (AEDL vs ADEL) | LC-MS/MS sequencing | Confirm Ala-Glu-Asp-Leu |
| Identity | LC-MS | Confirm m/z 446.45 |
| Purity | HPLC chromatogram | Confirm ≥98% |
| Net Peptide Content | Elemental/ChP-N or assay | Confirm active peptide fraction |
| Salt Form | TFA / acetate analysis | Confirm free peptide vs salt |
| Water Content | Karl Fischer | Confirm lyophilized stability |
| Endotoxin | LAL (on request) | Confirm cell-study suitability |
| Batch Traceability | Lot number & records | Confirm reproducibility |
| Solubility | TDS | Confirm water reconstitution |
| Storage | TDS | Confirm −20°C handling |
| MSDS / COA | Batch documents | Safe laboratory handling |
| Use Status | RUO declaration | Confirm research-only material |
Why Choose HDM BIO?
- Batch documentation provided with every shipment - COA, MSDS and packing list included
- Sequence you can verify - LC-MS confirms AEDL, with HPLC and LC-MS reports on request
- Research-grade purification - TFA-removed, ≥98% HPLC purity, endotoxin testing on request
- Custom synthesis - AEDL and related Khavinson short peptides made to order at mg to kg scale
- Direct manufacturer - Office: No.6299 Lanchi Second Road, Xi'an, Shaanxi, China
Storage & Handling
- Storage: −20°C, tightly sealed, protected from light and moisture (short-term 2–8°C)
- Handling: Reconstitute with sterile water for research protocols; use promptly after opening
- Shelf Life: 2 years frozen, sealed; follow validated laboratory SOPs
- Safety: Research use only. Not for human or animal administration; handle as a laboratory chemical
FAQ
Q: What is the MOQ and can I get a sample first?
A: MOQ for bulk raw powder is 1 g; milligram-scale R&D samples are available. Contact us to confirm availability.
Q: Can you provide a batch-specific COA?
A: Yes. Batch COA is provided with every shipment, including HPLC purity etc.
Q: What is the typical lead time?
A: We have fresh stock, ready for immediate shipment.
Q: Is the sequence AEDL or ADEL?
A: Bronchogen is Ala-Glu-Asp-Leu (AEDL). Some listings reverse Asp and Glu as ADEL, but AEDL and ADEL are different sequences with the same formula; we confirm AEDL by LC-MS for every batch.
Q: Does Bronchogen have a CAS number, and how is identity verified?
A: No CAS number has been assigned to this research peptide. Identity is confirmed by LC-MS against the expected mass (446.45 Da), and purity by HPLC; reports are available on request.
Q: Can Bronchogen be used in humans?
A: No. It is a research-only peptide with no approved indication and no completed randomized clinical trials. We supply it for in-vitro and laboratory research only, not for human or animal use.
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Shipping & Packing
Custom Synthesis & Cytogen Series in One Order
Research programs often need several short peptides. We can synthesize AEDL and the related Khavinson series together:
🧬 Custom AEDL synthesis - mg to kg scale, same HPLC/LC-MS release package
🔗 Related short peptides - Epithalon (AEDG) and other cytogen peptides synthesized to order
📊 Sequence verification - LC-MS/MS confirmation before shipment
🧪 Study-sized kits - TFA-removed or acetate formats, endotoxin-tested on request
[Request LC-MS Sample] [Request Custom Synthesis] [Get Bulk Quote]
Included with every shipment:
✓ Batch COA ✓ MSDS ✓ Packing List
Available on request:
✓ HPLC Report ✓ LC-MS Identity Report ✓ Endotoxin (LAL) Report
WhatsApp: +8619991242181
Email:sales@hdmbio.com
For bronchial-epithelium and short-peptide research, order the sequence-verified Bronchogen Peptide (AEDL) as a verified sample or a custom-synthesized bulk lot, and add related cytogen peptides to the same order.
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