Ampicillin Sodium Powder

 

 

• Equine Infections: Used in formulation research for respiratory tract infections (pneumonia, strangles caused by Streptococcus equi) and skin/soft tissue infections (abscesses, wounds) in horses.
• Livestock & Poultry: Evaluated for respiratory, urogenital and digestive tract infections caused by susceptible gram-positive and gram-negative bacteria in cattle, sheep, pigs and poultry.
• Companion Animals: Studied for injectable therapy of respiratory, skin, gastrointestinal and bone infections in dogs and cats (oral absorption of ampicillin is poor).
• Poultry-Specific: Investigated for omphalitis (navel infection) and clostridial infections such as necrotic enteritis in chickens.
• Combination Research: Used in β-lactamase inhibitor combination studies (e.g., ampicillin-sulbactam) to extend spectrum against enzyme-producing strains.

 

Test Item	Standard	Typical Result
Appearance	White or off-white powder	Consistent
Potency	845–988 μg/mg	910 μg/mg
Assay (HPLC)	≥98%	99.0%
Identity (IR)	Conforms to reference standard	Confirmed
Related Substances	Within specification	Pass
Loss on Drying	≤2.0%	0.8%
Residue on Ignition	≤0.5%	Compliant
Heavy Metals	≤10 ppm	Compliant
pH (10% solution)	8.0–10.0	9.1
Sterility	Sterile (injectable grade)	Pass

 

 

Each batch undergoes multi-step quality control before release to verify identity, potency, purity and sterility.

 

Raw Material QC → In-Process Control → Microbiological Potency Assay → HPLC Assay → IR Identity Verification → Related Substances (HPLC) → Loss on Drying → Heavy Metals → Residue on Ignition → pH Test → Sterility Test → Final Batch Release

 

Key evaluations include microbiological potency assay (845–988 μg/mg), HPLC active content assay, infrared (IR) identification, related substances analysis, loss on drying, heavy metal limits, residue on ignition, pH verification and sterility testing for injectable-grade material. Every commercial batch is supported by a batch-specific COA and relevant analytical documentation for incoming QC and supplier qualification.

 

 

Ampicillin Sodium Powder bulk pricing is driven by several key factors:

• Starting Material Costs: 6-APA (6-aminopenicillanic acid) availability and pricing directly influence semi-synthetic manufacturing expenses.
• Potency & Sterile Grade: Higher potency specifications and sterile injectable-grade production cost more than non-sterile material.
• Regulatory Compliance & Certification: GMP-standard sterile API batches with consistent COA and complete export documentation demand a higher price.
• Order Volume: Large-scale industrial or wholesale contracts receive steeper per-kilogram discounts than small-batch specialty orders.
• Logistics & Geography: Shipping distance, cold-chain/light-protection requirements and customs compliance add to the landed cost.

Contact HDM BIO for a current quotation and volume-based pricing.

 

 

• High-purity (≥98% / typical 99%+) aminopenicillin with controlled potency (845–988 μg/mg)
• Broad-spectrum semi-synthetic β-lactam suitable for injectable formulation research
• GMP-aligned production, ISO & HACCP certified quality system
• Full batch traceability and complete documentation (COA, MSDS, HPLC)
• Flexible supply: gram samples to ton-level bulk orders
• Global export to 70+ countries with full customs support

 

 

• Packaging: Foil bags for samples and moisture-proof fiber drums for bulk orders.
• Custom Packaging: OEM labeling available.
• Shipping Documents: COA, MSDS/SDS, commercial invoice, packing list and customs documentation available according to order requirements.
• Storage: Store tightly sealed in a cool, dry, light-protected environment. Shelf life: 24 months.
• Handling: For veterinary raw material use only; not for direct clinical administration.

 

 

Q1: What is Ampicillin Sodium Powder?

A: The water-soluble sodium salt of ampicillin, a semi-synthetic broad-spectrum aminopenicillin β-lactam antibiotic, supplied as veterinary raw material for injectable infection formulations.

 

Q2: What is the CAS number?

A: 69-52-3 (sodium salt); ampicillin free acid is 69-53-4.

 

Q3: Is Ampicillin Sodium a broad-spectrum antibiotic?

A: Yes. As an aminopenicillin, it is active against gram-positive bacteria and selected gram-negative bacteria including E. coli, Salmonella, Pasteurella and Proteus, but is inactive against β-lactamase-producing strains and Pseudomonas aeruginosa.

 

Q4: How does it work?

A: It binds to penicillin-binding proteins (PBPs), inhibiting peptidoglycan transpeptidation and bacterial cell wall synthesis, resulting in bactericidal activity.

 

Q5: Is Ampicillin Sodium suitable for oral administration?

A: Ampicillin has poor oral bioavailability compared with amoxicillin. The sodium salt form is primarily used for injectable/reconstitutable formulations.

 

Q6: What documents are provided with each batch?

A: Batch-specific COA, HPLC report, microbiological potency assay, IR identity records, sterility test data (injectable grade), MSDS/SDS and relevant export documentation are available according to order requirements.

 

Q7: What potency do you supply?

A: Standard 845–988 μg/mg (as ampicillin, anhydrous basis); typical batch result 910 μg/mg.

 

Q8: Where can I buy it from China?

A: HDM BIO supplies bulk Ampicillin Sodium Powder with batch COA and global export support.

 

Q9: How much does Ampicillin Sodium Powder cost?

A: Bulk pricing depends on 6-APA starting material costs, potency/sterile grade, regulatory compliance, order volume and logistics. Contact HDM BIO for a current quotation.

 

Q10: Is this product for human clinical use?

A: It is supplied as veterinary raw material and is not intended for direct clinical administration. Finished products manufactured from the material must comply with applicable local regulatory requirements.

 

 

• Batch-specific COA & MSDS
• GMP & ISO Certification
• Custom Bulk Pricing
• Research Samples Available