Wholesale Estradiol Undecylate Powder 99% CAS 3571‑53‑7 Fast Delivery
Core Highlights
Pharmaceutical-Grade Estradiol Undecylate Powder｜Purity ≥98.0% (HPLC)｜Sustained Estrogen Activity｜Batch Stable & Impurity-Controlled｜Full Compliance Documentation｜Suitable for Human Drug R&D, Steroid Synthesis, and Pharmacology Research｜Custom Packaging & Fast Delivery
Product Overview
Estradiol Undecylate Powder for research-grade preclinical and pilot-scale R&D (Estradiol Undecylate API) is a long-acting estrogen derivative of estradiol, designed for HRT research, steroid synthesis, and human drug formulation development. The ester modification prolongs in vivo activity and stabilizes plasma concentrations compared to natural estradiol, reducing dosing frequency.
The research-grade Estradiol Undecylate API is a white to off-white crystalline fine powder with high purity, traceable batch consistency, and GMP-compliant quality, suitable for preclinical pharmacology and formulation studies. It exhibits excellent chemical stability, high lipophilicity, is odorless, and has good flowability. This API serves as a core raw material for steroid hormone R&D, endocrine pharmacology studies, and novel estrogen formulation development.
Manufactured under GMP pharmaceutical intermediate standards, the Estradiol Undecylate Powder is intended for human drug R&D institutions, pharmaceutical companies, universities, and biotechnology labs. All production steps are strictly controlled to ensure compliance with global research and procurement standards.
COA
| Item | Specification | Result | |
| Appearance | White crystalline powder | Conform | |
| Identification | A: IR B: UV C: TLC Ultraviolet absorption Absorptivities at 281nm, calculated on the dried basis, do not differ by more than 3.0% |
Conform Conform |
|
| Solubility | Practically insoluble in water, Soluble in alcohol, acetone, dioxane, chloroform; Sparingly soluble in vegetable oils. | Conform | |
| Loss on drying | ≤0.50% | 0.08% | |
| Melting point | About 110℃ | 110.9~111.5℃ | |
| Total related substances | ≤2.0% | 0.53% | |
| Any individual impurity | ≤0.50% | 0.38% | |
| Residue on ignition | ≤0.10% | 0.08% | |
| Purity | ≥99% | 99.47% | |
| Conclusion | The product complies with the requirements of USP Standard. | ||
Mechanism of Action
Estradiol Undecylate Powder, a long-acting estrogen API for research-grade R&D, slowly hydrolyzes in vivo, releasing active estradiol. Estradiol binds ERα and ERβ, activating downstream signaling pathways and regulating gene expression. This modulates reproductive system development, bone density, lipid metabolism, and vascular protection, making it ideal for long-acting estrogen formulations and preclinical studies.The long-chain fatty acid ester delays hydrolysis, providing prolonged action and stable plasma concentrations, ideal for long-acting formulations and long-term research.
Applications of Estradiol Undecylate API
￭ Drug R&D: Raw material for long-acting estrogen formulations, HRT research, preclinical and pilot-scale studies, and formulation process optimization
￭ Pharmacology Research: In vitro cell studies and in vivo animal models to explore ER α/β mechanisms and endocrine modulation
￭ Pharmaceutical Intermediates: Synthesis of novel estrogen derivatives and steroid drugs for R&D
￭ Research Reagents: Supports university and lab studies in reproductive endocrinology, osteoporosis, and lipid metabolism
Benefits of Estradiol Undecylate API
￭ Long-Acting Estrogen Effect: The undecyl ester slows metabolism of research-grade estradiol, providing sustained release, stable plasma estrogen levels, and reduced dosing frequency
￭ Endocrine Modulation: Binds estrogen receptors α and β, regulating reproductive system development, bone density, lipid metabolism, and skin/mucosal tissue function
￭ Stable Bioavailability: Lipophilic structure enhances tissue absorption in preclinical studies, minimizes plasma fluctuations, and reduces formulation development risks
￭ Chemical Stability: Resistant to oxidation, maintains activity under proper storage, suitable for long-term research and production
Core Advantages
￭ Stable Purity: HPLC ≥99.0%, low impurities, batch-to-batch consistency
￭ Long-Acting Property: Ester modification ensures sustained release and reduces dosing frequency
￭ Flexible Supply: 10 g and kilogram-scale batches, fast global shipping
￭ Full After-Sales Support: Technical consultation, data verification, custom packaging
￭ Estradiol Undecylate Powder supports global bulk procurement to meet purchasing requirements for preclinical, pilot‑scale and formulation R&D, offering highly competitive prices.
Quality Assurance
￭ High-purity starting materials, free from heavy metals and harmful solvents, following ICH guidelines
￭ Multiple analytical checks: HPLC, IR, moisture, residue; all data traceable
￭ Controlled production: GMP cleanroom, fully monitored
￭ Storage: Sealed, light-protected packaging
FAQ
Q1: How does Estradiol Undecylate differ from regular estradiol?
A1: Ester modification slows metabolism, prolongs activity, stabilizes plasma levels, and reduces dosing frequency.
Q2: How to dissolve Estradiol Undecylate Powder?
A2: Dissolve in DMSO, ethanol, or methanol; dilute as needed. Filter with 0.22 μm membrane for cell experiments.
Q3: Are there harmful residues?
A3: GMP-compliant production, free from heavy metals and prohibited additives, fully traceable.
Q4: What is the mechanism of action?
A4: Ester hydrolyzes gradually, releasing active estradiol, activating ERα/β, and regulating gene expression to modulate reproductive, bone, lipid, and vascular physiology.
factory
Certificates
Shipping & Packing
Procurement & Support
Research-grade Estradiol Undecylate Powder/API with high purity, GMP-compliant, traceable batches is available worldwide for preclinical, pilot-scale, and formulation R&D.
￭ Sample testing
￭ Bulk procurement
￭ Custom packaging
￭ Fast delivery & technical support
Contact:Whatsapp & Mobile: +8619991242181
Email:sales@hdmbio.com
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