161258-30-6 Hexapeptide-11 powder | Firmness & Gene-Modulating Specialist | ≥98% HPLC

Core Selling Points

✅ ≥98% HPLC Purity: High-purity 161258-30-6 Hexapeptide-11 powder ensures consistent genomic signaling research.

✅ ATP & Sirtuin-1 Upregulation: Effectively targets cellular energy pathways to study skin rejuvenation.

✅ Validated Firming Efficacy: Promotes the synthesis of key extracellular matrix proteins in research models.

✅ China Peptide Manufacturer: Professional production facility specializing in functional and bio-mimetic peptides.

✅ Structural Identity Verification: Every batch confirmed by high-resolution LC-MS and purity chromatograms.

✅ Complete Documentation: Full support for lab audits, including COA, MSDS, and export clearance.

What Is Hexapeptide-11 Powder?

Hexapeptide-11 is a high-performance synthetic peptide originally derived from yeast fermentation but now precisely synthesized for high stability. In laboratory research, it is recognized for its unique ability to modulate gene expression related to skin firmness and elasticity. Hexapeptide-11 powder functions by stimulating the synthesis of collagen and glycosaminoglycans while upregulating Sirtuin-1 (the "longevity gene") and ATP levels. This dual action makes it a primary tool for studying the reversal of cellular senescence and the improvement of the skin's structural integrity.

The production of this peptide requires precise control over the amino acid sequence (Phe-Val-Ala-Pro-Phe-Pro) to ensure high biological fidelity. HDM BIO utilizes advanced solid-phase peptide synthesis (SPPS) and high-resolution purification to eliminate residual coupling agents and truncated fragments. We supply this high-stability powder to global cosmetic R&D centers and pharmaceutical research institutes focusing on age-delaying biotechnology.

Research-only disclaimer: For pre-clinical laboratory investigation only. Not for human clinical use, diagnosis, or medication.

What Are The Quality Specifications?

Item	Specification	Result
Appearance	White to off-white powder	Consistent
Purity (HPLC)	≥98%	99.96%
MS Identity	Consistent with reference standard	Confirmed
Conclusion	Cosmetic raw material requirement	Passed

Hexapeptide-11 vs Hexapeptide-9: What Are The Differences?

Feature	Hexapeptide-11	Hexapeptide-9
Primary Target	Firmness & ATP Stimulation	Regeneration & DEJ Repair
Mechanism	Gene Expression (Sirt-1)	Collagen IV & XVII Induction
Research Focus	Skin Elasticity / Sagging	Deep Wrinkles / Stretch Marks
Key Benefit	Cellular Energy Boost	Tissue Reconstruction
CAS Number	161258-30-6	1228371-11-6

Explore more Functional Peptides: Palmitoyl Tripeptide-5 · Acetyl Tetrapeptide-2 · Copper Peptide (GHK-Cu) · Pentapeptide-18

How Is Hexapeptide-11 Manufactured?

Our production follows a standardized cosmetic peptide synthesis protocol:

Chain Assembly: Stepwise synthesis of the sequence FVAPFP on a Rink Amide resin via Fmoc-SPPS.
Sequence Verification: Specialized monitoring of the Proline-Phenylalanine coupling to ensure zero deletion errors.
Acidic Cleavage: Selective removal of the peptide from the resin while preserving the structural integrity.
RP-HPLC Purification: Preparative reverse-phase HPLC isolation of the ≥98% pure monomeric fraction.
Quality Release: Final confirmation via high-resolution LC-MS to verify identity.

Structural Stability Control

The efficacy of the peptide depends on the precise sequence fidelity and the purity of the L-amino acid isomers. HDM BIO monitors every synthesis step to ensure our Hexapeptide-11 powder meets the highest analytical standards for research reproducibility.

What Is The Difference Between Research Grade And Cosmetic Grade?

Category	Research Grade	Cosmetic Grade
Primary Purpose	Pre-clinical / Lab research	Cosmetic formulation
Documentation	COA / HPLC / LC-MS / AAA	MSDS / COA / TDS
Purity Standard	Typically ≥98%	Typically ≥95%
Supply Channel	Specialized R&D Suppliers	Cosmetic Raw Material Suppliers

Why Is Supplier Qualification Important Before Purchasing Hexapeptide-11?

Gene Expression Validation: Qualification ensures the manufacturer has verified the peptide's ability to upregulate Sirt-1 and ATP in cell models.
Chiral Purity: Ensuring zero contamination from D-amino acids to maintain consistent biological response in research.
Zero Residual TFA: Efficient lyophilization must remove residual trifluoroacetic acid to protect sensitive dermal cell cultures.
Analytical Transparency: Reliable suppliers provide batch-specific LC-MS and HPLC chromatograms for definitive molecular confirmation.

Hexapeptide-11 Price & Bulk Order Guide 2026

MOQ: Flexible; from milligram research samples to kilogram-scale bulk orders.
Samples: Paid test samples available with full QC documentation.
Bulk pricing: Tiered pricing structure; larger volumes deliver highly competitive unit costs.
Lead time: Standard batches are usually in stock; bulk custom orders take 2-3 weeks.
Quotation: Contact our sales team for the latest formal quotation based on your specific requirements.

Why Choose HDM BIO As Your Supplier?

Firming Peptide Experts: Over 10 years of experience in the synthesis of genomic-modulating peptides.
High-Purity Guarantee: Advanced purification ensuring ≥98% purity and zero residual coupling agents.
Rigorous Analytical QC: Every batch confirmed by HPLC and high-resolution LC-MS.
Global Shipping Support: Fast, secure export to 70+ countries with customs-ready documentation.
Technical Support: Direct assistance with solubility, pH stability, and peptide formulation research.

Main Research Applications

Dermal Firmness Assays: Investigating the upregulation of elastin and collagen in aged skin models.
Cellular Energy Research: Measuring the impact of Hexapeptide-11 on ATP levels in keratinocytes.
Hair Follicle Stimulation: Researching the effects of the peptide on scalp microcirculation and hair density.
Gene Mapping Studies: Evaluating the modulation of Sirtuin-1 and other anti-aging genes.

FAQs

Q: What is Hexapeptide-11 used for in research?

A: It is primarily used to study skin firmness and cellular aging. Researchers utilize it to investigate how peptides can upregulate genes responsible for collagen production and cellular energy (ATP).

Q: Is Hexapeptide-11 effective for hair growth?

A: Yes, in a research context, it is often studied for scalp health. It is believed to improve the nutritional environment of the hair follicle by promoting microcirculation and strengthening the dermal matrix around the follicle bulb.

Q: How do I dissolve Hexapeptide-11 powder?

A: It is highly water-soluble. For laboratory solutions, it should be dissolved in deionized water or PBS. Stability is optimized at a pH range of 4.0 to 6.0.

Q: How should I store the powder to maintain its bioactivity?

A: Lyophilized powder should be stored sealed at -20°C, protected from light and moisture. When stored correctly, it remains stable for up to 24 months.