Thymopentin Powder CAS 69558‑55‑0 | High Purity Thymus‑Derived Immunomodulatory Peptide Supplier China

Core Selling Points

✅ ≥98% HPLC Purity Thymopentin Powder with Batch‑Specific COA Available

✅ Verified by HPLC, LC‑MS and Amino Acid Composition Analysis for 5‑mer short‑chain peptide identity confirmation

✅ China Peptide Manufacturer with Fmoc‑SPPS Production & GMP‑Aligned Quality System

✅ Specialized in short‑chain peptide deletion impurity & racemization by‑product control

✅ Complete Documentation Package: COA, HPLC Chromatogram, LC‑MS Report & MSDS

✅ Flexible Supply from Research Samples to Bulk Peptide Orders Worldwide

What Is Thymopentin Powder?

Thymopentin powder, also named TP‑5, Arg‑Lys‑Asp‑Val‑Tyr, is a synthetic 5‑amino‑acid immunomodulating peptide fragment derived from thymopoietin. Sequence: H‑Arg‑Lys‑Asp‑Val‑Tyr‑OH. It participates in T‑lymphocyte differentiation and immune‑cell function regulation, widely adopted in immunopharmacology, immune‑modulation mechanism, anti‑inflammation and thymus‑related pre‑clinical model research.

Manufactured via optimized Fmoc solid‑phase peptide synthesis under our GMP‑aligned quality system, our Thymopentin powder strictly controls amino‑acid racemization, single‑amino‑acid deletion impurities and truncated fragment by‑products, securing stable immunomodulatory bioactivity and consistent batch‑to‑batch reproducibility. HDM BIO serves global biochemistry laboratories, pharmaceutical R&D institutions and biological‑reagent manufacturers, covering milligram‑level research samples up to kilogram‑scale worldwide bulk procurement. This peptide raw material is restricted exclusively to laboratory research use and must not be directly used for human clinical administration.

What Are the Official Quality Specifications of Thymopentin Powder?

Every production batch of Thymosin Beta‑4 undergoes multi‑level QC testing including HPLC, LC‑MS and amino acid composition analysis within HDM BIO in‑house analytical laboratory. Batch‑specific COA will be issued for all purchase orders.

Item	Specification	Result
Appearance	White to off-white powder	Consistent
Purity (HPLC)	≥98%	99.33%
MS Identity	Consistent with reference standard	Confirmed
Conclusion	Cosmetic raw material requirement	Passed

Thymopentin vs Related Thymus‑Family Peptides

For buyers sourcing thymus‑derived immunomodulatory peptide raw materials for immune‑related pre‑clinical research, the comparison table clarifies core differences for targeted raw‑material selection：

Product	Target Mechanism	Structural Feature	Primary Research Application	CAS Number
Thymopentin	T‑cell differentiation & immune function modulator	5‑mer short‑chain peptide, active fragment of thymopoietin	Immunomodulation, lymphocyte function assay	69558‑55‑0
Thymosin α1	Broad‑spectrum immune‑regulatory peptide	28‑mer long‑chain peptide	Innate‑immunity and anti‑inflammation pre‑clinical study	62304‑98‑7

This section covers long‑tail keywords: thymopentin TP‑5 raw material, Arg‑Lys‑Asp‑Val‑Tyr research peptide, short‑chain immune‑modulatory peptide API.

How to Buy Thymopentin Powder from a Trustworthy Supplier?

When sourcing Thymopentin powder for immunology pre‑clinical research, R&D teams and international purchasers need to assess five core criteria to avoid supply‑quality risks:

HPLC purity validation: Confirm ≥98% HPLC purity with batch‑specific COA and full impurity chromatogram; pay special attention to amino‑acid racemization impurities and short‑chain deletion fragments which will interfere with immune‑cell functional assay results
Multi‑method structural confirmation: Peptide identity validated by HPLC, LC‑MS and amino‑acid composition analysis to confirm intact full‑length 5‑mer peptide
Complete batch documentation package: Guarantee each order obtains batch‑specific COA, HPLC chromatogram, LC‑MS report and MSDS to satisfy global import customs clearance and lab audit requirements
Qualified manufacturing system: Select China peptide manufacturer with mature Fmoc‑SPPS workflow and GMP‑aligned quality system, proven track record on short‑chain peptide racemization suppression technology
Global flexible supply: Confirm vendor can deliver both small‑scale research samples and large‑volume worldwide bulk peptide orders

Thymopentin Powder Price & Bulk Ordering Guide 2026

If you are searching for Thymopentin powder price, bulk quotation and delivery terms, please refer to key procurement information as follows:

Minimum Order Quantity: Flexible MOQ, milligram & gram‑scale research samples available; kilogram‑level worldwide bulk supply for sustained research projects
Sample Access: Trial research samples for lab evaluation; contact sales team to get formal sample quotation
Bulk Kilogram Pricing: Tiered pricing structure; larger bulk volume brings competitive unit price
Production Lead Time: Short‑chain peptide with optimized coupling process; sales will confirm exact production schedule upon formal inquiry
Shipping Options: Sealed cold‑recommended shipping worldwide; avoid prolonged room‑temperature exposure; we supply complete documentation package (batch‑specific COA, HPLC chromatogram, LC‑MS report, MSDS, commercial invoice, packing list) for global customs clearance

Thymopentin Powder Procurement Guide for Global Buyers

Before placing purchase orders for short‑chain immunomodulatory peptide raw materials, international procurement teams should finish these verification steps to mitigate potential risks:

Supplier qualification check: Confirm the manufacturer owns independent peptide‑synthesis workshop and QC lab with GMP‑aligned quality system, hands‑on experience on short‑chain peptide synthesis and racemization impurity control
Document inspection: Request pre‑shipment complete documentation package including batch‑specific COA, HPLC chromatogram, LC‑MS report and MSDS; require multi‑method peptide identity confirmation and impurity profile covering racemization by‑products and deletion‑truncated impurities
Product confirmation: Confirm purity standard, endotoxin level and cold‑storage requirement match your experimental design
MOQ & lead‑time confirmation: Verify research sample / bulk peptide worldwide availability, peptide production cycle and order‑adjustment policy
Shipping‑document confirmation: Make sure supplier can provide complete paperwork set to satisfy import requirements of your target region

About HDM BIO Thymopentin Manufacturing Capability

HDM BIO possesses more than 10‑year expertise in Fmoc‑SPPS peptide synthesis under GMP‑aligned quality system, specialized in short‑chain bioactive immunomodulatory peptide manufacturing with racemization‑risk control.

Dedicated Fmoc‑SPPS production lines; adopt optimized coupling reagent and temperature‑control strategy to reduce Asp‑related racemization side‑reactions
Independent analytical laboratory equipped with HPLC, LC‑MS and amino‑acid composition analysis instruments; specialized RP‑HPLC gradient workflow for separation of diastereomer and deletion fragment impurities
Peptide products exported worldwide to over 70 countries, supporting university labs, biotech startups and pharmaceutical R&D institutes
Stable annual production capacity for research‑grade peptide raw materials, supporting long‑term framework cooperation
Professional technical team experienced in thymus‑family peptide‑series synthesis and related analog custom modification

What Technical Challenges Exist in Thymopentin Synthesis & Production?

Thymopentin is a 5‑mer short‑chain peptide containing aspartic‑acid residue. Controlling amino‑acid racemization, removing single‑residue deletion fragments and separating diastereomeric impurities constitute core technical bottlenecks separating qualified peptide manufacturers from low‑grade suppliers.

Key production challenges:

‑ Aspartic‑acid residue is prone to racemization and aspartimide side‑reactions during coupling and cleavage process, generating diastereomer impurities difficult to separate

‑ Short‑chain peptide synthesis easily produces single‑amino‑acid deletion by‑products; partial truncated fragments have similar retention time on RP‑HPLC ‑ Multiple charged residues (Arg, Lys, Asp) bring complex solubility change during purification process

‑ Single HPLC test is insufficient for full quality judgement; multi‑validation via HPLC, LC‑MS plus amino‑acid composition analysis is mandatory to guarantee intact full‑length 5‑mer peptide for immunology functional biology assays

How Does Thymopentin Powder Work in Laboratory Research?

As synthetic disulfide‑cyclized vasopressin prodrug peptide, Terlipressin Acetate powder is enzymatically cleaved in‑vitro / in‑vivo to release active lysine‑vasopressin, selectively activating vasopressin V1 receptor to induce splanchnic vasoconstriction and reduce portal pressure. It serves as core experimental reagent for V1‑receptor pharmacology profiling, portal‑hypertension animal‑model assay, hepatorenal‑syndrome pre‑clinical evaluation and vasopressin ligand structure‑activity‑relationship exploration. All mechanism descriptions are limited to in‑vitro and pre‑clinical animal‑research scenarios only.

How Is Thymopentin Powder Manufactured at HDM BIO?

Thymopentin requires strict full‑process control for aspartate racemization suppression, deletion‑fragment removal and lyophilization, operated within our GMP‑aligned quality system.

Read related guide: Disulfide‑Containing Peptide API Manufacturing Guide | Fmoc SPPS Technology Explained

Complete Thymopentin Powder Manufacturing Workflow

Raw‑material QC of Fmoc‑amino‑acid building blocks → Step‑wise 5‑mer peptide SPPS coupling with low‑racemization coupling system on solid resin → Resin cleavage & global deprotection with optimized scavenger combination → Crude peptide pretreatment → Multi‑stage preparative‑HPLC purification (remove diastereomer racemization impurities & deletion‑fragment impurities) → Buffer‑exchange → Vacuum lyophilization → Full multi‑method QC testing (HPLC, LC‑MS, amino‑acid composition analysis for identity verification, impurity profiling & endotoxin test) → Batch‑specific COA issuance → Light‑proof, low‑moisture sealed packaging

QC Inspection Workflow

Incoming raw‑material QC → In‑process racemization risk monitoring → HPLC purity testing (diastereomer‑resolving gradient method) → LC‑MS molecular‑weight & full‑sequence verification → Supplementary amino‑acid composition analysis for peptide identity confirmation → Racemization & deletion‑impurity quantitative analysis → Moisture & heavy‑metal testing → Residual‑solvent & endotoxin detection → Final batch‑release approval under GMP‑aligned quality system

Core Process Highlights

‑ Low‑racemization coupling condition to suppress Asp‑related diastereomer formation ‑ Optimized RP‑HPLC gradient for baseline separation of racemization diastereomers and deletion truncated fragments ‑ Multi‑step high‑resolution HPLC to remove structurally‑similar short‑chain peptide related‑substances ‑ Multi‑level identity confirmation: HPLC, LC‑MS plus amino‑acid composition analysis verifying intact full‑length 5‑mer Thymopentin peptide ‑ Lyophilized solid stable stored at −20 °C sealed condition; avoid repeated freeze‑thaw cycles, reconstituted peptide solution shall be aliquoted and stored at −80 °C.

What Are the Main Application Scenarios of Thymopentin Powder?

T‑cell immunology research: T‑lymphocyte differentiation assay, immune‑cell cytokine secretion profiling
Immune‑regulation pre‑clinical research: Immune‑deficiency animal model, immune‑reconstitution efficacy evaluation
Anti‑inflammatory pharmacology research: Inflammatory‑response modulation and immune‑homeostasis study
Peptide formulation development: Short‑chain peptide injectable formulation stability screening
Biomedical reagent preparation: Laboratory reference standards for thymus‑series peptide research
Short‑chain charged‑peptide‑process‑development research: Asp‑containing short‑peptide synthesis benchmark compound

Why Choose HDM BIO As Your Thymopentin Powder Supplier?

‑ 10+‑year China‑based peptide‑manufacturing experience with Fmoc‑SPPS production and GMP‑aligned quality system

‑ Specialized capability for Thymopentin peptide synthesis and purification, effectively reduce racemization diastereomers and single‑residue deletion impurities

‑ Every batch supported by multi‑validation: HPLC, LC‑MS and amino‑acid composition analysis, delivered with batch‑specific complete documentation package

‑ Complete batch‑wise production‑traceability documents for Thymopentin Powder

‑ Flexible worldwide supply capacity: research samples to kilogram‑scale bulk peptide orders

‑ Global‑export service covering more than 70 countries worldwide

‑ Professional technical team supporting thymus‑family peptide research and custom‑analog synthesis consulting

FAQs About Thymopentin Powder

Q: Where can I buy Thymopentin powder from China?

A: HDM BIO is a Chinese peptide manufacturer with Fmoc‑SPPS production and GMP‑aligned quality system, specialized in short‑chain thymus‑derived immunomodulatory peptide. We deliver high‑purity Thymopentin powder for global pharmaceutical R&D teams and bioreagent laboratories, flexible worldwide supply from research samples to bulk peptide orders.

Q: What documents should a qualified Thymopentin supplier provide?

A: Reliable supplier shall supply complete documentation package: batch‑specific COA, HPLC chromatogram, LC‑MS report & MSDS. Peptide identity is verified by HPLC, LC‑MS and amino‑acid composition analysis; racemization diastereomer impurity‑testing data are available upon request.

Q: What is the CAS number of Thymopentin Powder?

A: The CAS registry number of Thymopentin Powder is 69558‑55‑0.

Q: What purity grade of Thymopentin powder can you deliver?

A: Standard research‑grade ≥98% HPLC purity. Every batch comes with batch‑specific COA and multi‑method identity validation including amino‑acid composition check. Higher‑purity specifications and thymus‑series custom‑peptide‑analog synthesis are available for special experimental requirements.

Q: How should lyophilized Thymopentin powder be stored?

A: Store sealed at −20 °C, keep away from light and moisture. Strictly avoid repeated freeze‑thaw cycles. Aqueous reconstituted solution should be prepared into single‑use aliquots and stored at −80 °C.

Q: Can I get Thymopentin research samples before bulk purchase?

A: Yes. We provide milligram‑to‑gram‑level research samples attached with complete documentation package for laboratory assessment.

Q: What is the MOQ for bulk Thymopentin powder worldwide orders?

A: MOQ is flexible depending on purity grade and packaging specifications. We support small‑scale research samples and large‑volume worldwide bulk peptide orders for different‑project requirements.

Q: What is the amino‑acid sequence of Thymopentin Powder?

A: H‑Arg‑Lys‑Asp‑Val‑Tyr‑OH.

Scientific Review

Reviewed by:

HDM BIO Peptide Technical Team

Expertise:

Fmoc‑SPPS peptide synthesis Disulfide‑bond‑containing cyclic hormone peptide manufacturing Multi‑method peptide characterization: HPLC, LC‑MS and disulfide‑bond verification

Last Updated: August 2026

Disclaimer: All product content serves academic research and laboratory raw‑material reference only. Not for human clinical use, diagnosis or treatment.