Dipeptide-2 powder (CAS 24587-37-9) | High-Stability Anti-Edema & Lymphatic Drainage Peptide | ≥98% HPLC

Core Selling Points

✅ ≥98% HPLC Purity: Certified high-purity for consistent anti-edema research.

✅ Lymphatic Drainage Focus: Effectively studied for its ability to improve fluid circulation.

✅ Validated Anti-Puffiness: Primary tool for investigating the reduction of under-eye bags.

✅ China Peptide Manufacturer: Specialized production facility for advanced functional dipeptides.

✅ Structural Identity Verification: Every batch confirmed by high-resolution LC-MS.

✅ Complete Documentation: Full support for lab audits, including COA and MSDS.

What Is Dipeptide-2 Powder?

Dipeptide-2 is a synthetic, low-molecular-weight peptide consisting of the amino acids Valine and Tryptophan. In laboratory research, it is recognized for its unique ability to enhance lymphatic circulation and prevent fluid accumulation in the tissues. Dipeptide-2 powder acts by facilitating the drainage of interstitial fluid, making it an essential research tool for investigating the treatment of localized edema and the reduction of puffiness in the periorbital area.

The production of this high-stability dipeptide requires precise control over the enantiomeric purity of the Valyl-Tryptophan sequence. HDM BIO utilizes advanced solid-phase peptide synthesis (SPPS) and preparative RP-HPLC to ensure the highest biological fidelity. We supply this high-stability Dipeptide-2 powder to global cosmetic R&D centers and pharmaceutical research institutes focusing on microcirculation and anti-fatigue biotechnology.

Research-only disclaimer: For pre-clinical laboratory investigation only. Not for human clinical use, diagnosis, or medication.

What Are The Quality Specifications?

Item	Specification	Result
Appearance	White to off-white powder	Consistent
Purity (HPLC)	≥98%	99.68%
MS Identity	Consistent with reference standard	Confirmed
Conclusion	Cosmetic raw material requirement	Passed

Dipeptide-2 vs. Caffeine: What Are The Differences?

Feature	Dipeptide-2	Caffeine
Mechanism	Lymphatic Drainage Facilitator	Adenosine Receptor Antagonist
Primary Target	Interstitial Fluid Circulation	Lipolysis & Vasoconstriction
Action Duration	Sustained Signaling	Transient Stimulation
Research Focus	Anti-Edema / Eye Bags	Fat Reduction / Micro-relief
Stability	High Peptide Stability	High Chemical Stability

How Is Dipeptide-2 Manufactured?

Our production follows a standardized cosmetic peptide synthesis protocol:

Chain Assembly: Stepwise synthesis of the Val-Trp sequence on a Rink Amide resin via Fmoc-SPPS.
Sequence Verification: Specialized monitoring of the Tryptophan coupling to prevent oxidative degradation.
Acidic Cleavage: Selective removal of the peptide from the resin while preserving structural integrity.
RP-HPLC Purification: Preparative reverse-phase HPLC isolation of the ≥98% pure monomeric fraction.
Quality Release: Final confirmation via LC-MS to verify the identity of the Dipeptide-2 powder.

Structural Stability Control:

The efficacy of the peptide depends on the precise sequence fidelity and the absence of diastereomers. HDM BIO monitors every synthesis step to ensure our products meet the highest analytical standards for research reproducibility.

What Is The Difference Between Research Grade And Cosmetic Grade?

Category	Research Grade	Cosmetic Grade
Primary Purpose	Pre-clinical / Lab research	Cosmetic formulation
Documentation	COA / HPLC / LC-MS / AAA	MSDS / COA / TDS
Purity Standard	Typically ≥98%	Typically ≥95%
Supply Channel	Specialized R&D Suppliers	Cosmetic Raw Material Suppliers

Why Is Supplier Qualification Important Before Purchasing?

Supplier qualification is critical to ensure that the dipeptide is free from residual coupling agents and unreacted amino acids. For researchers, it is essential that the manufacturer validates the monomeric purity through HPLC, as impurities can interfere with sensitive lymphatic drainage assays. Reliable suppliers provide batch-specific chromatograms and ensure the removal of trifluoroacetic acid (TFA) to protect the viability of cellular models used in edema research.

Price & Bulk Order Guide 2026

MOQ: Flexible; from 1g research samples to 5kg+ industrial bulk orders.
Samples: Paid test samples available with full QC documentation.
Bulk pricing: Tiered pricing structure; larger volumes deliver highly competitive unit costs.
Lead time: Standard batches are usually in stock; bulk custom orders take 2 weeks.
Quotation: Contact our sales team for the latest formal quotation based on your specific requirements.

Why Choose HDM BIO As Your Supplier?

Antioxidant Experts: Over 10 years of experience in the synthesis of glutathione and its derivatives.
High-Purity Guarantee: Advanced purification ensuring ≥99% purity and zero oxidized GSSG.
Rigorous Analytical QC: Every batch confirmed by HPLC, LC-MS, and NMR.
Global Shipping Support: Fast, secure export to 70+ countries with customs-ready documentation.
Technical Support: Direct assistance with solubility, redox stability, and formulation compatibility.

Main Research Applications

Lymphatic Circulation Mapping: Investigating the speed of fluid drainage in skin-equivalent models.
Anti-Edema Efficacy: Measuring the reduction of localized swelling in 3D tissue assays.
Periorbital Research: Studying the attenuation of dark circles and puffy eye bags.
Barrier Recovery: Evaluating the impact of dipeptides on the skin's moisture balance.

FAQs

Q: What does Dipeptide-2 do for skin research?

A: It is primarily studied for its ability to improve lymphatic drainage and reduce edema. Researchers utilize it to investigate how peptides can decrease fluid accumulation under the eyes and improve overall tissue microcirculation.

Q: Does Dipeptide-2 help with puffy eyes in models?

A: Yes. In research contexts, Dipeptide-2 is a key component for studying the reduction of puffy eyes. It is often evaluated alongside Palmitoyl Tetrapeptide-7 to assess synergistic effects on under-eye bags.

Q: Is Dipeptide-2 safe for topical formulation research?

A: In laboratory settings, it is considered a non-toxic peptide with a safe profile for topical skin-model assays. It is highly water-soluble and maintains stability at a pH range of 4.5 to 6.5.

Q: How should I store the powder to maintain its bioactivity?

A: Lyophilized powder should be stored sealed at -20°C, protected from light and moisture. Correct storage ensures the peptide remains stable and bio-active for up to 24 months.