Lypressin Acetate Powder CAS 50‑57‑7 | High Purity Antidiuretic Nonapeptide Supplier China

Core Selling Points

✅ ≥98% HPLC Purity Research‑Grade Peptide Material

✅ LC‑MS Full Cyclic Octapeptide Sequence & Disulfide Bond Verification

✅ Batch‑Specific COA, HPLC & MS Test Reports Available

✅ Optimized Fmoc SPPS Cyclization Workflow, In‑house Independent QC Laboratory

✅ Global Export Documentation & Cross‑border Cold‑chain Logistics Support

✅ Custom Peptide Purification & Salt‑form Adjustment Service

What Is Lypressin Acetate Powder?

Lypressin Acetate powder, also known as lysine vasopressin acetate, is a synthetic cyclic nonapeptide hormone analog with one intramolecular disulfide bond formed between two cysteine residues. Structurally close to arginine vasopressin, it exerts antidiuretic, vasopressor and uterine smooth‑muscle contracting biological activities by binding V2, V1a and V1b receptors. This peptide is widely used for endocrine pharmacology, renal water‑balance mechanism, vasopressin‑receptor interaction and pre‑clinical drug‑screening research.

Manufactured by optimized Fmoc solid‑phase peptide synthesis, controlled on‑resin oxidative folding for intramolecular disulfide bond formation, multi‑stage gradient HPLC purification and strict lyophilization process, our Lypressin Acetate powder effectively reduces mis‑folded disulfide isomer, deletion‑sequence and oxidation‑related impurities, delivering stable biochemical activity and consistent batch‑to‑batch quality. HDM BIO supports global biochemistry laboratories, pharmaceutical R&D institutions and bioreagent manufacturers from milligram‑level lab samples up to kilogram‑scale bulk procurement. This peptide raw material is strictly for laboratory research purpose only and shall not be directly used for human clinical administration.

What Are the Official Quality Specifications of Lypressin Acetate Powder?

Every production batch of Lypressin Acetate undergoes dual QC testing (HPLC + LC‑MS) in HDM BIO in‑house analytical laboratory. Batch‑specific COA will be issued for all bulk purchase orders.

Item	Specification	Result
Appearance	White to off-white powder	Consistent
Purity (HPLC)	≥98%	99.77%
MS Identity	Consistent with reference standard	Confirmed
Conclusion	Cosmetic raw material requirement	Passed

Lypressin Acetate vs Other Vasopressin‑Family Peptides

For buyers sourcing vasopressin‑related cyclic peptides for endocrine and renal pharmacology research, the comparison table below helps target raw‑material selection:

Product	Target Mechanism	Structural Feature	Primary Research Application	CAS Number
Lypressin Acetate (Lysine Vasopressin)	Activates V2 / V1a / V1b receptors; antidiuretic effect, moderate vasoconstriction	Cyclic nonapeptide with intramolecular disulfide bond; Lys at position‑8	Renal water homeostasis, endocrine pharmacology, vasopressin‑receptor binding assay	50‑57‑7
Arginine Vasopressin (AVP)	Endogenous antidiuretic hormone, strong V1a vasopressor activity	Cyclic nonapeptide, Arg at position‑8	Cardiovascular‑renal model, neuroendocrine research	113‑79‑1
Desmopressin Acetate	Selective V2‑receptor agonist, minimal vasopressor activity	Modified AVP analog, de‑amino‑Cys1, D‑Arg8	V2‑receptor selective drug screening, diabetes insipidus related study	16679‑58‑6

This section covers long‑tail keywords: lypressin acetate lysine vasopressin, cyclic disulfide‑bond vasopressin peptide, lypressin for renal pharmacology research.

How to Buy Lypressin Acetate Powder from a Trustworthy Supplier?

When sourcing Lypressin Acetate powder for endocrine, renal‑physiology and vasopressin‑receptor pre‑clinical research, R&D teams and international purchasers need to assess five core criteria to avoid supply‑quality risks:

HPLC purity validation: Confirm ≥98% HPLC purity with complete chromatogram, focus on mis‑folded disulfide‑bond isomer impurities which heavily affect bio‑activity
LC‑MS structural confirmation: Verify full nonapeptide molecular weight, validate correct intramolecular disulfide‑bond formation
Batch‑specific documentation: Ensure each order can obtain independent batch COA, HPLC and LC‑MS test reports
Mature synthesis capability: Choose suppliers with proven manufacturing experience for cysteine‑rich cyclic peptide with controlled oxidative folding process
Global export capability: Confirm supplier can provide complete documents for international customs clearance

HDM BIO provides research‑grade Lypressin Acetate with full traceable quality records, flexible MOQ for lab trial batches and long‑term bulk procurement.

Lypressin Acetate Powder Price & Bulk Ordering Guide 2026

If you are searching for Lypressin Acetate powder price, bulk quotation and delivery terms, please refer to key procurement information as follows:

Minimum Order Quantity: Flexible MOQ, milligram & gram‑scale laboratory trial samples available; kilogram‑level bulk supply for sustained research projects
Sample Access: Trial samples for lab evaluation; contact sales team to get formal sample quotation
Bulk Kilogram Pricing: Tiered pricing structure; larger bulk volume brings competitive unit price
Production Lead Time: Lead time varies with order quantity; cyclic folding process requires dedicated production cycle; sales will confirm exact schedule upon formal inquiry
Shipping Options: Standard sealed cold‑recommended shipping; we supply commercial invoice, packing list and MSDS for global customs clearance

Final quotation is affected by purity grade, extra custom testing items, special packaging and international logistics fees. Please contact our sales team for up‑to‑date formal quotation.

Lypressin Acetate Powder Procurement Guide for Global Buyers

Before placing purchase orders for cyclic disulfide‑bond‑containing peptide raw materials, international procurement teams should finish these verification steps to mitigate potential risks:

Supplier qualification check: Confirm the manufacturer owns independent peptide synthesis workshop and QC lab with rich experience on oxidative folding cyclic peptide production
Document inspection: Request pre‑shipment batch COA, HPLC chromatogram and LC‑MS report; pay special attention to disulfide‑isomer impurity testing data
Product confirmation: Confirm purity standard, impurity profile and cold‑storage requirement match your experimental design; aqueous reconstituted solution is prone to disulfide‑bond rearrangement and oxidation
MOQ & lead‑time confirmation: Verify sample / bulk availability, production cycle and order adjustment policy
Shipping‑document confirmation: Make sure supplier can provide all required paperwork for import customs clearance of your target region

About HDM BIO Lypressin Acetate Manufacturing Capability

HDM BIO has more than 10‑year expertise in Fmoc solid‑phase peptide synthesis and complex cyclic disulfide‑bond peptide manufacturing.

Dedicated SPPS production lines equipped for cysteine‑containing sequences; multiple mature oxidative‑folding workflows for intramolecular disulfide‑bond formation
Independent analytical laboratory equipped with HPLC, LC‑MS, moisture tester and heavy‑metal detection instruments; special analytical method to separate and quantify disulfide mis‑isomer impurities
Peptide products exported to over 70 countries, supporting university labs, biotech startups and pharmaceutical R&D institutes
Stable annual production capacity for research‑grade peptide raw materials, supporting long‑term framework cooperation
Professional technical team experienced in vasopressin‑family cyclic peptide synthesis, folding‑process optimization and related analog custom modification

Our peptide manufacturing site runs dedicated Fmoc‑SPPS production lines, in‑house preparative‑HPLC purification and complete LC‑MS analytical workflow.

What Technical Challenges Exist in Lypressin Acetate Synthesis & Production?

Lypressin Acetate is a cyclic nonapeptide relying on intramolecular disulfide‑bond between two cysteine residues. Controlling correct oxidative folding and suppressing mis‑paired disulfide is the core technical difficulty separating qualified peptide manufacturers from low‑level suppliers.

Key production challenges:

Two cysteine residues may form intermolecular dimer by‑product instead of target intramolecular ring during oxidation folding
Mis‑folded disulfide‑bond isomers have very similar molecular weight, hard to separate by conventional HPLC and will completely damage receptor‑binding bio‑activity
Cysteine residues are vulnerable to oxidation during synthesis, cleavage, purification and lyophilization steps
Acetate‑salt counter‑ion balance needs precise buffer‑exchange control to meet batch‑consistent salt‑form specification
Even high nominal HPLC purity cannot guarantee correct folding; disulfide‑isomer specific testing is mandatory for functional cell or receptor‑binding assays

HDM BIO applies controlled‑dilution oxidative‑folding condition to reduce intermolecular dimer, multi‑stage high‑resolution preparative‑HPLC for isomer separation, full‑batch LC‑MS monitoring and strict impurity profiling. These measures minimize mis‑folded isomer, dimer and oxidized by‑products, ensuring correct cyclic nonapeptide structure and stable batch‑to‑batch biological performance.

How Does Lypressin Acetate Powder Work in Laboratory Research?

As a classic lysine‑type vasopressin cyclic peptide, Lypressin Acetate powder binds to V2 receptors on renal collecting‑duct epithelial cells to promote water re‑absorption and produce antidiuretic effects. Meanwhile it activates V1a receptors to trigger vascular‑smooth‑muscle contraction and can stimulate uterine smooth‑muscle contraction via related receptor pathways.

It is widely adopted as key reference compound for water‑balance regulation research, vasopressin‑receptor pharmacology, diabetes insipidus cell/animal model, vasopressin‑family drug‑candidate screening and structure‑activity‑relationship study. All mechanism descriptions are limited to in‑vitro and pre‑clinical animal research scenarios only.

How Is Lypressin Acetate Powder Manufactured at HDM BIO?

Lypressin Acetate needs strict full‑process control for cysteine protection, oxidative folding, disulfide‑isomer removal and acetate‑salt buffer exchange across synthesis, cleavage, purification and lyophilization.

Read related guide: Cyclic Disulfide Peptide Manufacturing Guide | Fmoc SPPS Technology Explained

Complete Lypressin Acetate Powder Manufacturing Workflow

Raw‑material QC of Fmoc‑amino‑acid building blocks → Nonapeptide SPPS step‑wise coupling (orthogonal Cys side‑chain protection) → Resin cleavage & global deprotection → Crude peptide pretreatment → Controlled dilution oxidative folding for intramolecular disulfide‑bond cyclization → Multi‑stage preparative‑HPLC purification (remove disulfide isomer & dimer impurities) → Buffer‑exchange for acetate‑salt formation → Vacuum lyophilization → Full QC testing (disulfide‑isomer profiling, LC‑MS identity confirmation) → Batch COA issuance → Light‑proof sealed low‑moisture packaging

QC Inspection Workflow

Incoming raw‑material QC → In‑process coupling & folding‑state monitoring → HPLC purity testing → LC‑MS molecular‑weight verification → Disulfide‑isomer impurity quantitative analysis → Moisture & heavy‑metal testing → Residual‑solvent detection → Final batch release approval

Core Process Highlights

Orthogonal cysteine side‑chain protection strategy, support controlled on‑off‑resin oxidative cyclization

Optimized dilute‑solution folding condition to suppress intermolecular peptide dimer by‑product

Multi‑step high‑resolution HPLC to separate hard‑to‑remove mis‑folded disulfide‑bond isomer impurities

LC‑MS confirmation for correctly cyclized nonapeptide molecular signature

Acetate‑salt buffer‑exchange process to guarantee consistent counter‑ion form; lyophilized solid stable stored at −20 °C; aqueous solution is unstable, aliquot and freeze quickly after reconstitution.

What Are the Main Application Scenarios of Lypressin Acetate Powder?

Renal‑endocrine pharmacology research: Antidiuretic mechanism, renal collecting duct water‑reabsorption, water‑electrolyte balance cell and animal‑model experiments
Vasopressin‑receptor study: V1a, V1b, V2 receptor binding assay, vasopressin‑family ligand structure‑activity‑relationship exploration
Cardiovascular & smooth‑muscle research: Vascular vasoconstriction, uterine smooth‑muscle contraction related pre‑clinical test
Disease‑model research: Diabetes insipidus and vasopressin‑related endocrine‑disorder model research
Biomedical reagent preparation: Reference standards and experimental control reagents for vasopressin‑family peptide research
Cyclic peptide technology development: Disulfide‑bond peptide process‑development benchmark compound

Why Choose HDM BIO As Your Lypressin Acetate Powder Supplier?

10+ years China‑based cyclic peptide manufacturing experience, specialized in cysteine‑containing disulfide‑bond vasopressin‑series peptides
Mature controlled oxidative‑folding workflow, effectively reduce intermolecular dimer and mis‑folded disulfide‑isomer impurities
Full‑batch disulfide‑isomer impurity profiling and LC‑MS cyclic‑structure validation for every production lot
Complete batch‑wise production traceability documents for Lypressin Acetate
Flexible supply capacity: milligram lab samples to kilogram‑scale bulk peptide orders
Global export service covering more than 70 countries worldwide
Professional technical team supporting vasopressin‑family peptide research and cyclic‑peptide custom analog synthesis consulting

FAQs About Lypressin Acetate Powder

Q: Where can I buy Lypressin Acetate powder from China?

A: HDM BIO is a Chinese cyclic disulfide‑bond peptide supplier delivering high‑purity Lypressin Acetate powder for global pharmaceutical R&D teams and bioreagent laboratories. We provide small research samples and large‑volume bulk orders, with full export documents and international shipping support.

Q: What documents should a qualified Lypressin Acetate supplier provide?

A: Reliable supplier shall supply batch‑specific COA, HPLC chromatogram, LC‑MS identity report, MSDS and complete production traceability records; disulfide‑isomer impurity test data is available upon request.

Q: What is the CAS number of Lypressin Acetate?

A: The CAS registry number of Lypressin Acetate is 50‑57‑7.

Q: What purity grade of Lypressin Acetate powder can you deliver?

A: Standard research‑grade ≥98% HPLC purity. Higher‑purity specifications and vasopressin‑series custom peptide analog synthesis are available for special experimental requirements.

Q: How should lyophilized Lypressin Acetate powder be stored?

A: Store sealed at −20 °C, keep away from light and moisture. Avoid repeated freeze‑thaw cycles. Aqueous reconstituted solution tends to produce disulfide‑bond rearrangement; prepare single‑use aliquots and store at −80 °C, do not store long‑term under refrigeration.

Q: Can I get Lypressin Acetate samples before bulk purchase?

A: Yes. We provide milligram‑to‑gram‑level trial samples attached with complete COA and test documents for laboratory assessment.

Q: What is the MOQ for bulk Lypressin Acetate powder?

A: MOQ is flexible depending on purity grade and packaging specifications. We support small‑scale research batches and large‑volume bulk orders for different‑project requirements.

Q: What is the amino‑acid sequence of Lypressin Acetate?

A: Cyclic (Cys1‑Cys6) H‑Cys‑Tyr‑Phe‑Gln‑Asn‑Cys‑Pro‑Lys‑Gly‑NH₂ acetate salt (Lysine Vasopressin).

Scientific Review

Reviewed by: HDM BIO Peptide Technical Team Expertise: Peptide synthesis Cyclic disulfide‑bond hormone‑peptide manufacturing Analytical chemistry & disulfide‑isomer impurity profiling

Last Updated: August 2026

Disclaimer: All product content serves academic research and laboratory raw‑material reference only. Not for human clinical use, diagnosis or treatment.